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The 8 Best migraine relief of 2025

Are you trying to find migraine relief among various brands on the market but aren’t sure where to begin? To assist you in finding the right one, we’ve put together a list of the 7 best to help you pick the perfect one!

We investigated and evaluated a number of the top-selling migraine relief on the market in order to create our list of the best. Making a decision among the many options available is never simple. There are an infinite number of models available, each with a distinct price. And as you’ll find out, the best options aren’t usually the ones you imagine! This comparison is rich and relevant because of the numerous factors that were employed. You will find products featured in this ranking not only based on their pricing but also on their features and other customers reviews. To write this review, we completed 17 hours of research and did 31 migraine relief tests. You won’t need to pick products at random any more. If you’re unsure of what to look for, browse our list and consult the buying guide!

An overview of our top picks

Table of contents

The best migraine relief you can buy today

SaleNo. 1
Amazon Basic Care Migraine Relief Acetaminophen, Aspirin (NSAID) and Caffeine Tablets, Pain Reliever/Pain Reliever Aid, 250mg, 200 Count (Packaging may vary)
  • ACTIVE INGREDIENTS: Amazon Basic Care Migraine Relief contains acetaminophen 250 mg, aspirin 250 mg (NSAID), and caffeine 65 mg; compare to the active ingredients in Excedrin Migraine
  • MIGRAINE PAIN: The pain of migraine headaches can disrupt your lifestyle; Amazon Basic Care Migraine Relief caplets help to treat migraine pain so you can get back to doing what you enjoy
  • COATED CAPLETS treat migraine headache pain; caplets are capsule-shaped tablets
  • FOR ADULTS: Amazon Basic Care Migraine Relief caplets treat migraine headaches in adults; use a 2-caplet dose for migraine pain relief; under 18 years of age, ask a doctor
  • GLUTEN FREE: This migraine relief medicine is gluten free
No. 2
Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 200 Count
  • One bottle of 200 Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms
  • Excedrin Migraine works in 3 ways to relieve migraines: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance the pain relief effect
  • Delivers migraine relief, including acting as a migraine headache pain reliever and relieving sensitivity to light and sound, and nausea
  • Excedrin migraine pain relief caplets combine acetaminophen, aspirin and caffeine
  • Head pain relief medicine delivers a powerful triple action formula with two pain relievers and an amplifier
No. 3
MigreLief Original Triple Therapy with Puracol - Nutritional Support for Migraine Sufferers - 60 Caplets/1 Month Supply
  • Adults and teens with migraine - MigreLief provides effective nutritional support for migraine sufferers and is the original dual patented dietary supplement recommended by neurologists and headache specialists for over 25 years.
  • Trusted formula makes a difference - MigreLief has changed the lives of hundreds of thousands of migraine sufferers worldwide. MigreLief takes a Triple Therapy approach to help maintain healthy cerebrovascular tone and function (blood vessels in the brain) and to help maintain healthy mitochondrial energy reserves (the powerhouse of cells) which is very important to migraine sufferers.
  • Proven ingredients - formulated by migraine supplement pioneer. Based on scientific evidence, Akeso's Chief Scientific Officer Curt Hendrix was the first to discover the unique combination of Magnesium, Riboflavin (Vitamin B-2) and Puracol Feverfew for migraine sufferers for which he received two United States patents.
  • #1 nutritional option for migraine sufferers, safe & effective - MigreLief is non-prescription, vegetarian, drug free, caffeine free and non-GMO. Does not contain butterbur, wheat, gluten, salt, soy, milk or dairy, nuts, corn, caffeine, artificial flavorings or preservatives.
  • Made in the USA - ingredients tested by independent 3rd party laboratories, and manufactured in certified facilities in the United States. Packaging may vary.
SaleNo. 4
Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 24 count
  • One bottle of 24 Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms
  • Migraine medicine that delivers effective migraine headache pain relief
  • Delivers migraine relief, including acting as a migraine headache pain reliever and relieving sensitivity to light and sound, and nausea
  • Excedrin migraine pain relief caplets combine acetaminophen, aspirin and caffeine
  • Delivers a powerful triple action formula with two pain fighters and an amplifier
  • Migraine relief medicine available in convenient caplet form
  • For some, these Excedrin Migraine caplets relieve migraine pain in 30 minutes
  • HSA and FSA eligible product
No. 5
ONLYCARE Migraine Relief Cap, Soothing Headache Hat, Upgraded Odorless Gel Ice Head Wrap, Hot and Cold Therapy, FSA or HSA Eligible Headache Ice Pack for Tension and Stress(Black)
  • FSA or HSA Eligible, Great Investment for Migraine Relief Cap - Have you ever found yourself wanting to close eyes, or staying in a calm and relaxed? This hat keeps cool for a period and creates a dark & lightproof environment.
  • Hot and Cold Therapy - Simply freeze the migraine ice cap for 2 hours or microwave it for 40 seconds to apply heat or cold where you need it most for a soothing and relaxing experience(After unpacking the product, it is recommended to place it in a natural environment for ventilation for 2 hours. Before refrigeration, please be sure to seal the cold compress cap in the provided packaging bag to prevent the product from absorbing odors.)
  • 2025 New Odorless Material - Different from other old head ice packs, our headache relief cap is made of exclusive gel, has no unpleasant odor, keeps cold longer, and maintains maximum flexibility even after long freezing, which is a solid all-around upgrade.
  • Ergonomic Design - The curve of this headache relief hat is designed as per ergonomics with 360° surrounding gel design, expanding the cold compress scope by 25% and perfectly fit the head form (head circumference is about 20-24 inches) of most people. Meanwhile, it covers the worst migraine spots: forehead, temple and eyehole and provides moderate pressure, not stiff as ice cube, closely and comfortably suits your head.
  • Natural Relief Method - Pulling down the Coolchill Cap to the wing of nose below eyes, the U shape design can perfectly restrict the light stimulation and create a dark & peaceful space.
SaleNo. 6
Amazon Basic Care Migraine Relief Geltabs, Acetaminophen, Aspirin (NSAID) and Caffeine, 80 Count
  • ACTIVE INGREDIENTS: This product contains acetaminophen 250 mg, aspirin 250 mg (NSAID: nonsteroidal anti-inflammatory drug) and caffeine 65 mg. Compare to the active ingredients of Excedrin Migraine Geltabs
  • PAIN RELIEF: Amazon Basic Care Migraine Relief Geltabs offer headache pain relief so you don't miss out on life's special moments
  • MIGRAINE TREATMENT: Just one dose helps to temporarily reduce headache pain caused by migraines
  • PAIN RELIEVER AND PAIN RELIEVER AID: Amazon Basic Care Migraine Relief Geltabs combine acetaminophen 250 mg, aspirin 250 mg (NSAID: nonsteroidal anti-inflammatory drug) and caffeine 65 mg to treat migraine pain
  • GLUTEN FREE: These headache pain relief pills are gluten free
No. 7
Migrastil Migraine Stick Rollon - Fast Cooling Comfort for Your Head. Aromatherapy with Peppermint & Other Essential Oils. Metal Roller. Made in USA by Basic Vigor
  • The original Migraine Stick. See why so many people love our Migraine Stick for migraine care. Enjoy cooling comfort with pure Peppermint, Spearmint & Lavender oils in a base of fractionated coconut oil.
  • Just apply to your temples, forehead and back of neck at the first signs of unease. Our easy-glide roller ball offers a no-mess, leak-resistant option. Contains no artificial fillers or additives.
  • Migraine Stick is strong enough to help with migraines but also helps with other types of headaches including tension and sinus headaches.
  • With their portable size, Migraine Sticks make wonderful nurse accessories for work and are truly travel essentials. TSA-compliant.
  • These are great self care items for women and men. Ethically made in the USA and never tested on animals.
No. 8
TheraICE Migraine Relief Cap PRO, Headache Relief Cap, Ice Face Mask, Cold Compress Head Wrap for Tension Headache Relief, Stress & Hangover, FocusZone Technology Provides Extra Cooling & Pressure
  • FocusZones Technology: Dive deep into relief with our proprietary, patent-pending FocusZones technology. Our migraine relief products are designed for critical pain points of a migraine— the Temples and Occipital regions— ensuring precision-targeted therapy right where you need it.
  • Enhanced Gel Thickness: Experience the ultimate sensation of therapeutic massage combined with cooling. Our enhanced gel thickness not only offers prolonged, intense cold therapy but also mimics the soothing pressure of a massage that alleviate tension, stress, or hangover symptoms."
  • Long Lasting Cooling Effect: TheraIce migraine headache relief cap contains thicker gel composition to ensures that you're granted a longer-lasting, more profound cooling effect, extending your moments of respite. This face ice mask
  • High-Tech PRO Design: Beyond function, we prioritize form. Step into the future with our sleek, state-of-the-art PRO design. The migraine relief revamped outer shell doesn't just promise a premium feel but speaks of sophistication, merging technology with top-tier aesthetics.
  • Reusable, Flexible, Adjustable: Our migraine relief cap is designed as a head wrap to accommodate various head sizes comfortably. The migraine mask can be frozen and reused for multiple sessions of cooling therapy and the use is versatile, makes it ideal for headaches, migraines, tension relief, and hangover recovery.
SaleNo. 9
RENPHO Eye Massager with Remote, Heat, Compression, Mothers Day Birthday Gifts for Mom Women, Eyeris 1 Sleep Mask FSA HSA, Headache Massager Scalp for Strain Relief, Migraine Relief, Reduce Stye Eye
  • HSA FSA Eligible Item Only List: this eye massager for migraine relief is FSA or HSA eligible, and can be purchased with FSAs and HSAs. Easily use your flex spending account or health savings account to purchase the eye massager for eye care!
  • 2 Levels Soothing Heat Compress: The built-in heating pads provide a comfortable temperature of 104℉/113℉ (40℃/45℃ ), better for relieving eye strain, eye puffiness, dry eyes, improve sleep, etc. Our eye massager for migraine can effectively help you be refreshed after a long day of work or study
  • 2 Levels Compression Eye Massage: With the high-tech motor, and trigger point massage, RENPHO eye massager replicates the human massage effect of squeezing and kneading, helping to refresh your eyes, reduce styes, sore eyes, dark circles. You can choose between 2 adjustable compression intensity settings to enjoy a vacation for your eyeballs and a better sweet dream
  • Upgraded Version Adopts Remote & Touch Control: RENPHO eyeris 1 new version eye massager can switch modes at will and be controlled by remote control or touch. You can also enjoy listening to your favorite music tracks through the Bluetooth speaker while massaging your eyes. Bluetooth Name: Eye Massager. 𝗡𝗼𝘁𝗲 𝟭: Renpho eye massager is not suitable for those who have undergone eye operation, retina condition, cataract, glaucoma, etc.
  • Mother's Day Gifts/Birthday Gifts Ideas: Renpho eye massager with heat and cooling is a personalized gift for women/men ideas, which can help them relieve eye strain during their long days at work. Especially after the nurses work the night shift and teachers work at their desks for a long time at night
  • RENPHO eye sleep mask can block out light and help soothe tired eyes by providing a relaxing warmth that can reduce stress and enhance sleep quality
  • 180° Foldable & Lightweight Portable: Our electric eye strain relief device with a storage bag that can be folded into smaller, so you can take it to the office, airplane, or traveling. In addition, the head strap can be easily adjusted in size and suitable for all teenagers and adults
  • Reliable Customer Service: Every Renpho massager uses a well-built package & a good unboxing experience. Renpho is well-known for the highest quality products and the best customer service team
No. 10
GenCare - Headache Relief Acetaminophen with Aspirin (NSAID) & Caffeine (300 Caplets) Value Pack | Head Pain, Muscle Aches, Back Pain & Body | Generic Excedrin Extra Strength
  • HEAD & BODY PAIN RELIEF - Each caplet of GenCare Extra Strength Headache Relief contains 250mg of Acetaminophen, 250mg of Aspirin (NSAID) and 65 mg of Caffeine to give fast and extended pain relief of headaches, muscle aches, back pain and migraines.
  • HUGE SAVINGS - Save big compared to big box stores and your local pharmacy with effective over the counter relief with our bulk size 300 caplet value bottle. Always be prepared and in stock with effective pain relief pills on hand for when your family needs it the most. Compare to generic Excedrin Extra Strength active ingredients.
  • ACTS FAST - Headaches, migraines and pain can hit at the worst time. 65 mg of caffeine in each pill help energize you and restore mental focus so you can accomplish the task at hand. 65 mg of caffeine is about as much a cup of coffee, so avoid this product before bed.
  • HELPS WITH ACHES & PAINS - Relieve Back pain, neck pain, toothaches, menstrual cramps, arthritis, joint pain and more in one easy to swallow caplet. Directions: Adults and children 12 years and older : take 2 caplets every 6 hours . Do not exceed 8 caplets in a 24 hour period.
  • 100% SATISFACTION GUARANTEE - Say goodbye to headaches and pain! GenCare backs up each bulk savings bottle of Extra Strength Headache Relief with our 100% Customer Satisfaction Guarantee. Join thousands of satisfied customers.
SaleNo. 11
Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 100 Count
  • One bottle of 100 Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms
  • Excedrin Migraine works in 3 ways to relieve migraines: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance the pain relief effect
  • Delivers migraine relief, including acting as a migraine headache pain reliever and relieving sensitivity to light and sound, and nausea
  • Excedrin migraine pain relief caplets combine acetaminophen, aspirin and caffeine
  • Head pain relief medicine delivers a powerful triple action formula with two pain relievers and an amplifier
  • Migraine relief medicine available in convenient caplet form
  • For some, these Excedrin Migraine caplets relieve migraine pain in 30 minutes
  • HSA and FSA eligible product
No. 12
Amazon Basic Care Headache Relief Geltabs, 80 Count
  • ACTIVE INGREDIENTS: This product contains acetaminophen 250 mg, aspirin 250 mg (NSAID, nonsteroidal anti-inflammatory drug) and caffeine 65 mg; compare to the active ingredients in Excedrin Extra Strength Geltabs
  • PAIN RELIEF: Amazon Basic Care Extra Strength Headache Relief Geltabs offer headache and arthritis pain relief; also provides pain relief for toothaches, muscular aches and premenstrual and menstrual cramps
  • EXTRA STRENGTH: When you need something strong to temporarily reduce pain, these extra strength geltabs will help you feel better so you don't miss out on life's special moments
  • PAIN RELIEVER AND PAIN RELIEVER AID: Extra Strength Headache Relief Geltabs combine acetaminophen 250 mg, aspirin 250 mg (NSAID, nonsteroidal anti-inflammatory drug) and caffeine 65 mg to help relieve minor aches and pains when you need it the most
  • GLUTEN FREE: These pain relief pills are gluten free
No. 13
Migraine Relief Cap, Soothing Headache Ice Face Mask Products, Hot and Cold Therapy, Migraine Headache Relief Cap for Migraine, Sinus, Puffy Eyes, Tension, Stress and Hangover(Pink)
  • [Headache and Migraine Relief] - The Conbella migraine relief cap is a natural drug-free relief for headaches and migraines. The headache relief cap is soft and comfortable with no unnecessary pressure which directly targets problematic areas like the temples, forehead, sides, back of the neck, and eyes. The hangover cap is perfect for releasing head pain, puffy eyes, bruises, swelling, soreness, tension, and sinus headaches.
  • [Comprehensive 360°Cold Or Hot Therapy] - The Conbella headache cap provides comprehensive cold and hot therapy, specifically targeting areas for quicker recovery. This form-fitting gel migraine cap can be frozen to apply cold therapy or microwave for heated therapy. As a headache mask, it eliminates the need for messy wraps, uncomfortable ice packs, inserts, or awkward band straps, serving as your primary solution for headache relief. It's a reusable headache hat that combines the advantages of both hot and cold therapy in one migraine relief solution.
  • [One Size Fits Most] – The one-piece wrap design of our hangover hat delivers comforting, gentle compression to ease throbbing headaches and intense migraine episodes. With its natural, secure fit, you can unwind without concern of it slipping off. This migraine relief mask accommodates all face shapes, head sizes, and eye contours, guaranteeing a calming and restful sensation. Our wearable cold cap for migraines offers the utmost comfort you require for various types of headaches. Its flexible compression ensures an ideal fit for anyone in search of relief from migraines. It's genuinely adaptable and versatile as a solution for headache and migraine relief.
  • [Freezes Fast, Stays Cold Longer] - The medical-grade inner gel material freezes within just one to two hours and retains coldness for an extended duration compared to traditional ice packs. For prolonged and continuous relief, it's recommended to acquire two or more migraine caps for women, ensuring you always have one ice pack for head available for immediate use while another migraine mask remains prepped and ready to go.
  • [Dark Light-Blocking Headache Hat] - There are two ways to wear this ice cap for migraines. One method of this migraine miracle cap involves exposing your eyes, allowing you to engage in activities while alleviating various facial and head discomforts. The other approach of this head relief cap entails covering your eyes, providing a shield from light during rest without the need to draw curtains, enabling your entire body to experience relief and relaxation.
  • 【Odor-Free Upgraded Materials】The ice hat is an odorless product designed for providing relief from migraines and headaches. The ice cap for headaches is commonly referred to by different names such as cold cap, ice cap, or migraine hat. The purpose of this product is to alleviate pain and discomfort by applying a cold sensation to the head. The head ice pack migraine is typically filled with gel that can be chilled in the freezer before use. The odorless nature of the migraine headache relief cap ensures that there are no unpleasant smells associated with its usage.
No. 14
BeKOOOL Migraine Gel Sheets - 4 Count
  • NATURAL MIGRAINE AND FEVER REDUCER - Non-medicated, cold compress alternative that stays where you stick it and is safe to use with oral medication
  • ADJUSTABLE - Quickly trim the non-toxic, natural gel sheet with scissors to fit the forehead, cheek or neck
  • VALUE PACK - Stock up your medicine cabinet with this non-expiring, natural product so you're ready when a migraine or fever strikes
  • Doctor recommended
No. 15
MIGRASTIL Migraine Stick with Magnesium Cooling Peppermint Eucalyptus Essential Oil Topical Magnesium for Headache Support. Made in The USA 10 ml
  • Enhanced Effectiveness: Experience the power of magnesium combined with our signature blend of essential oils for potent support against migraines. Contains no artificial fillers or additives.
  • Topical Magnesium Benefits: Magnesium Chloride, a vital mineral, is absorbed through the skin to address headaches and promote relaxation, aiding in calming nerves and soothing muscles.
  • Portable: Carry it in your pocket or purse for easy access whenever headaches arise. With their portable size, Migraine Sticks make wonderful nurse accessories for work and are truly travel essentials. These are great self care items for women and men. TSA-compliant.
  • Versatile Solution: Migraine Stick is strong enough to help with migraines but also helps with other types of headaches including tension and sinus headaches. Apply to your temples, forehead, and neck for soothing comfort.
  • Quality Assurance: Migraine Stick is crafted in the USA with care for your safety. Cruelty-free and vegan. The leak-resistant metal roller ball ensures mess-free application every time. Ethically made in the USA and never tested on animals.
No. 16
Migraine Relief Cap, Headache Relieve Cap Mask Products, Cooling Odorless Gel Ice Head Wrap for Tension, Stress,Hangover & Puffy Eyes
  • Natural Relief Cap for Instant Headache Relief: Qnoon Migraine Relief Cap offers 360° gel coverage, expanding cold compress area by 25%. Its stretchable design fits most heads, targeting the forehead, temples, and eyes with moderate, comfortable pressure
  • Beat Headaches with Natural Relief Cap:The Qnoon Headache Cap provides natural relief by shrinking blood vessels, slowing nerve conduction, and easing muscle tension with cold. It helps alleviate migraines and light sensitivity without medication
  • Long-Lasting Cold Relief Cap:Our headache relief hat uses advanced materials and gel to stay cool longer and be reused. It offers deep headache relief, improves sleep, and helps with tension, inflammation, sinus issues, and puffy eyes
  • Odorless and Non-Toxic Material:Our headache hat is made from non-toxic, odorless materials, staying fresh even after long refrigeration. Store it in the bag provided and refrigerate it. Use it anytime without worrying about unpleasant smells
  • Dual Hot and Cold Relief Cap: The migraine mask offers both hot and cold options. For cold relief, refrigerate the hat for 1 hour. For hot relief, microwave at room temperature for 30 seconds. Refer to the instruction manual for details

How to choose a good migraine relief

Does the idea of finding a fantastic migraine relief make you anxious? When it comes to purchasing this product, specifically when deciding which model to select, has your head been spinning between options? You are not alone if that is the case. We are aware of the pressure involved in the purchasing process!

Your presence here indicates that you are interested in migraine relief. Before choosing which product would be the best for your needs after being inundated with information, locate a reliable source with genuine selections. You can get that information from a variety of sources, including buying guides and rating websites, word-of-mouth recommendations from friends and family, online discussion forums where users can share their own experiences, product reviews that can be found all over the internet, and YouTube channels. You can only get the right product through exhaustive analysis. But you realize that’s not always simple. In order to ease your concerns, we have taken the time to develop a list of the top migraine relief products available right now. You might be wondering how we came up with the list. How was this buying guide developed?

First, we used our algorithms to gather as much reliable data as we could about these products. To verify all the data gathered, we used both artificial intelligence and a lot of algorithms.
Then, our experts used criteria that are recognized in the business to evaluate them according to their quality to price ratio, allowing us to choose the top migraine relief on the market right now!

The selection of the goods is not arbitrary. Before creating a list, we take into account a number of factors. Below are some of the criteria discussed:

Brand Value: What happens if you choose a dubious brand just because it appears to be a good deal? So the likelihood of receiving a product with a short shelf life increases. That is due to the fact that well-known brands have a reputation to uphold, while others do not. Top migraine relief brands strive to provide some distinctive traits that set them apart from the competition. So, hopefully one or more of the items on our list will be perfect for you.

Features: Useful features are all you need, not tons of them. We consider the important aspects and select the top migraine relief based on those.

Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products with higher specifications, but with the right balance.

Quality: A product’s quality may always be quantified with the aid of numbers. We look for goods with better standards that strike the proper balance. The best quality product that gets highly appreciated and recommended by experienced users.

Customer ratings:  Would it be accurate to suggest that the migraine relief were used by hundreds of customers before you? Superior ratings indicate that many customers had better service.

Customer Reviews: Like ratings,  provide you with accurate and reliable information about the product from genuine customers. Customer ratings are very important to all of us because they contain accurate and reliable information about the customer service we received from several hundred customers.

Seller Rank: This is very intriguing! Not only do you need a good migraine relief, you also need a product with rising sales that is trendy. It accomplishes two goals. First, the expanding user base proves the quality of the product. Second, given that number, producers must be able to offer greater quality and after-sales support.

Value: You get what you pay for, they say, so consider the value. Cheap isn’t always good and expensive isn’t always bad. However, that does not imply that spending a lot of money on a product that is flashy but underwhelming is a good idea. Before adding them to the list, we make an effort to evaluate how much value you can get for your money from your migraine relief.

Durability: Durability and reliability are closely related concepts. You will benefit from a strong and long-lasting migraine relief for months and years to come.

Product availability: Products come and go, and new ones replace the old ones. Most likely, a few new features and required changes were made. What use is it to use a supposedly good product if the maker no longer supports it? We make an effort to highlight products that are current and offered by one or more trustworthy sellers, if not more.

Negative Reviews: Yes, we do take that into account as well! The goods with the majority of bad reviews are filtered out and disregarded when we choose the best-rated one on the market.

These are the standards by which we selected our migraine relief. Do we end our process there? Hell no. The most crucial fact about us that you should be aware of is that we regularly update our website with current and pertinent information. We have one more layer of filtration since we place the greatest importance on reader satisfaction. Please let us know if any product included here is incorrect, irrelevant, subpar, or simply out of date. We always value your opinions, and we’ll work hard to make any necessary corrections to our list in response to them.

Why should you believe us?

There are now thousands of possibilities for these products on Amazon, but choosing the best one can be difficult and time-consuming. And what migraine relief should you purchase in 2022?

This guide is the result of more than 10 years of experience in researching, testing and writing about many topics. Each member of our team is an authority in their area. We read every article we could find online and every consumer review on every retail website for seven hours. Additionally, we discovered a ton of websites that offered helpful resources, including buying tips and thorough information on migraine relief.