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The 8 Best cat urine enzymatic cleaner of 2024

Are you trying to find cat urine enzymatic cleaner among various brands on the market but aren’t sure where to begin? To assist you in finding the right one, we’ve put together a list of the 7 best to help you pick the perfect one!

We investigated and evaluated a number of the top-selling cat urine enzymatic cleaner on the market in order to create our list of the best. Making a decision among the many options available is never simple. There are an infinite number of models available, each with a distinct price. And as you’ll find out, the best options aren’t usually the ones you imagine! This comparison is rich and relevant because of the numerous factors that were employed. You will find products featured in this ranking not only based on their pricing but also on their features and other customers reviews. To write this review, we completed 19 hours of research and did 27 cat urine enzymatic cleaner tests. You won’t need to pick products at random any more. If you’re unsure of what to look for, browse our list and consult the buying guide!

An overview of our top picks

Table of contents

The best cat urine enzymatic cleaner you can buy today

No. 1
Rocco & Roxie Supply Co. Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray
  • Certified Gentle And Safe: Chlorine free and color safe. Safe to use around pets and children. No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (cri)
  • Eliminates Stains, Odors And Residue: If it’s gross, it’s gone. Not just the stain, but the stink. From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all.
  • Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen.
  • Enzyme Activated: The key is getting to the problem deep-down. This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated.
  • 100% Satisfaction Guaranteed: An Amazon best seller—for a reason. If your stains and odors aren’t gone, neither is your money. We’ll refund it in full.
SaleNo. 2
Simple Solution Cat Extreme Pet Stain and Odor Remover | Enzymatic Cleaner with 3X Pro-Bacteria Cleaning Power | 32 Ounces
3,000 Consomer Reviews
Simple Solution Cat Extreme Pet Stain and Odor Remover | Enzymatic Cleaner with 3X Pro-Bacteria Cleaning Power | 32 Ounces
  • DESIGNED FOR CAT MESSES - Simple Solution Cat Extreme Stain and Odor Remover is specifically formulated to eliminate tough cat odors and stains, such as urine, feces, and vomit, while discouraging repeat spraying.
  • TRIPLE THE CLEAN- The 3X cleaning formula is specifically designed to remove tough stains and odor from carpets, bedding, fabric, and most water-safe surfaces.
  • STRONGER AND BETTER - The professional strength formula of our Simple Solution Cat Extreme Stain & Odor Remover breaks down organic cat messes and is safe around children and pets when used as directed.
  • NEW PATENTED MULTI-FUNCTIONAL SPRAYER - Now designed with a new patented 3-in-1 nozzle sprayer (foam, mist, and stream).
  • MADE IN THE USA - Simple Solution Cat Extreme Stain and Odor Remover is proudly manufactured in the USA.
SaleNo. 3
Sunny & Honey Pet Stain & Odor Miracle - Enzyme Cleaner for Dog Urine Cat Pee Feces Vomit, Enzymatic Solution Cleans Carpet Rug Car Upholstery Couch Mattress Furniture, Stain Eliminator (32FL OZ)
  • Enzyme Cleaner - This Pet Stain and Odor Miracle is a powerful enzyme cleaner that effectively tackles tough stains and odors from dog and cat urine and poop, leaving your carpets, upholstery, couch, mattress, and any other surface spotless and fresh-smelling.
  • Odor Eliminator - Not just a stain remover, it's a potent odor eliminator too! It neutralizes even the strongest pet odors, making it the ideal dog and cat urine odor eliminator. Your home will smell as good as new.
  • Pet-Friendly - This pet stain and odor remover is safe for your pets and kids. It's the perfect pet cleaner for messes, stains & odor.The bio-enzymatic formula is biodegradable, non-toxic, and scented with essential oils - and it's Leaping Bunny certified.
  • Easy to Use - Just spray the pet stain carpet cleaner on the affected area, let it sit, then wipe it off. It's that simple to say no to pee and stains.This puppy pee spray cleaner make cleaning up after your pet a breeze
  • Fresh as a Daisy - Let's face it - the stench of organic matter sticks to surfaces. When you don't have a second to do a whole carpet cleanse, use this carpet deodorizer for pet urine on any surface that the pets threw up, peed, pooped, or drooled on. Thanks to the scented oils, it'll smell great asap!
No. 5
Begley's Natural Pet Stain and Odor Remover - Pet Odor Eliminator for Home - Pet Urine Enzyme Cleaner - Pet Carpet Cleaner for Pets - Enzymatic Cleaner for Dog Urine, Cat Pee, Feces, Fluids - 24 Ounce
  • Pet Stain Remover for Carpet - The powerful enzyme action of the carpet stain remover pet cleaner for carpet, breaks down organic proteins causing lingering odors and stubborn stains that encourage pets to repeat their actions rather than covering them up. The enzyme cleaner for dog urine and poop eliminates evidence of household "accidents" effectively discouraging pets from repeating their actions
  • Powerful Cleaner - The enzyme carpet cleaner for dog urine odor eliminator spray tackles stains and smells at their root to clean and neutralize, completely removing 100% of the organic matter, making it the perfect carpet stain remover for old stains. This cat pee enzyme cleaner for cat urine works on urine, feces, vomit, blood, drool, and other odors and stains
  • Multi Surface Cleaner - A versatile odor neutralizer and pet stain carpet cleaner solution that can clean it all. This enzymatic cleaner cat urine odor eliminator spray is safe and effective for use in cars, households, laundry, bedding, furniture, kennels, litter boxes, and living areas. Works on most surfaces like tile, wood, fabric, carpet, and upholstery, great as a carpet cleaner spray, mattress cleaner and stain remover, and more
  • Natural Cleaning Power - Begley's dog pee spray cleaner is safe to use around pets and children. Formulated using plant-derived ingredients and is scented with essential oils, leaving behind a fresh and clean citrus scent. The pet urine odor eliminator spray is also Cruelty-Free, Leaping Bunny Certified, and a USDA Certified Biobased Product
  • Environmentally Friendly - Ed Begley, Jr. has long been an advocate in sustainable living and spreading awareness on environmental issues. Ed believes in using natural plant-derived ingredients and is proud of his eco-responsible household product line. Ed’s vision of a greener future is embedded in Begley’s biobased formulas that are equal to or more effective than their conventional alternatives
No. 6
Stuart Pet Supply Co. Professional Strength Pet Odor Eliminator | Urine Odor Remover | Pet Urine Enzyme Cleaner | Pet Stain and Odor Remover | Enzymatic Cleaner for Dog Urine and Cat Urine
  • ✔️ Scientifically Formulated Stain & Odor Eliminator: Removes the stain and stink from your pets
  • ✔️ Enzyme Powered: Completely removes all pet stains and odors for urine, feces, vomit & drool.
  • ✔️ Child & Pet Safe: Natural enzyme formula is the safest way to remove pet stains and odors.
  • ✔️Multi Surface: Use on carpet, wood, furniture, rugs, crates, upholstery, outdoor carpets etc.
  • ✔️ 100% Guaranteed-Proudly Made In The USA: If you're not 100% HAPPY, we will refund it in full
No. 7
Simple Solution Pet Urine Destroyer | Enzymatic Cleaner with 2X Pro-Bacteria Cleaning Power | Targets Urine Stains and Odors | 1 Gallon
  • TOUGH ON URINE - Simple Solution Pet Urine Destroyer combines Pro-Bacteria and Enzymes in a formula that neutralizes the toughest urine odors and discourages future marking.
  • ELIMINATE STAINS – Simple Solution’s enzymatic cleaner technology lifts urine stains leaving your carpet stain and odor free.
  • MULTIPLE USES – Our pet odor and stain remover is safe to use on carpet, upholstery, bedding, fabric toys, clothing and other water-safe surfaces in your home when used as directed.
  • CARPET SAFE – Certified by the Carpet and Rug Institute, our Pet Urine Destroyer is safe to use on all colorfast carpets when used as directed.
  • SAFE FOR THE HOME – Simple Solution pet urine remover is safe for use around pets and your household when used as directed.
No. 8
Bulldogology Bio-Enzymatic Pet Stain & Odor Remover - Pet Carpet Enzyme Cleaner for Cat and Dog Pee, Pet Stain Remover for Carpet and Floors, Dog Stain Remover and Odor Neutralizer (32 oz)
  • REMOVES PET STAINS & ODORS: Completely clean and remove tough stains along with anything gross or smelly mess. Easily eliminate dog and cat pee, feces, vomit, drool, urine or other organic hard to remove spills. Our bio-enzyme formula targets and neutralizes all mess leaving your house smelling fresh and clean!
  • NATURAL-DERIVED CLEANER: Using powerful natural enzymatic with advanced surfactant technology to activate and combine a deep cleaning formula that remove stains and odors from carpet, rug, pet bed, furniture, hardwood, clothing, kennel, litter box, and all other areas where stains occur.
  • PET & CHILDREN SAFE: Not only it’s chlorine free and color safe it’s especially safe around your pets and kids. There are no hazardous residue after use, that also means unpleasant smell, our formula keep your family safe while you’re home smelling cleaner.
  • NEUTRALIZE EVERY TIME: When your pets accidents happen, there’s a chance it might again, but with each spray, the solutions removes and completely neutralizing the scent, this helps and prevent repeat mistakes.
  • LIFETIME SATISFACTION: If for any reason your stains and odors isn’t removed, we want to give you a piece of mind with our 100% satisfaction guarantee. Just ask and we’ll instantly send a full refund.
No. 9
Urine Off Kitten & Cat Pet Stain Remover | Fresh Scent Carpet Cleaner | Bio Enzymatic Stain & Urine Odor Eliminator | Pet Safe Cleaner | 1 gal.
  • BIO ENZYMATIC — Not just a cover up, our cat enzyme urine cleaner directly targets uric acid & effectively removes all components of urine stain and pet odor.
  • ELIMINATES ODORS — Leaves surfaces smelling fresh and clean while discouraging territory marking behavior by removing strong odors from cat urine.
  • MULTI–SURFACE — Urine, stain & odor remover can be used on carpets, rugs, hardwood floors, tile, linoleum and much more.
  • PLANET & PET FRIENDLY — Proudly made in the USA and formulated without bleach & chlorine. USDA certified biobased product that is safe for pets and people.
  • URINE OFF — From new kittens to everyday messes, Urine OFF's pet friendly cleaning supplies can help keep your home clean and fresh.
No. 10
Natural Elements Yard Odor Eliminator | Enzyme Odor Control | Non-Toxic | Dog, Cat, Urine, & Feces | Unscented, Non- Masking (1 Gallon)
  • 🐶 Powerful Enzyme Formula: Our Unscented Yard Odor Eliminator harnesses the power of natural enzymes to break down and neutralize pet odors, leaving your outdoor spaces smelling fresh and clean.
  • 🐶 Versatile Outdoor Solution: This multipurpose cleaner effectively targets pet odors and serves as a proficient cleaner for various outdoor surfaces, such as grass, artificial turf, concrete, and patios, ensuring a consistently odor-free environment.
  • 🐶 Effortless Application: Natural Elements Yard Odor Eliminator, available in a user-friendly 1-gallon size, can be efficiently applied using a 1-gallon garden sprayer, a soaking method, or by direct pouring onto the affected spots. This pre-diluted formula requires no additional water or mixing, making it ready for immediate use. It can also be incorporated into your regular watering or cleaning routine for proactive odor management.
  • 🐶 Safe for Pets and the Environment: Our eco-friendly formula is non-toxic, biodegradable, and safe for pets, plants, and wildlife, giving you peace of mind as you maintain a clean and odor-free outdoor space. This product is safe for lawns and landscaping.
  • 🐶 Biologically Based, Scientifically Validated: Natural Elements creates trusted outdoor products, proudly made in the USA with the highest quality ingredients.
No. 11
Nature's Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 32 oz
1,429 Consomer Reviews
Nature's Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 32 oz
  • FOR CAT URINE MESSES: Begins to break down and remove stains immediately on contact.
  • POWERFUL FORMULA: Just soak the affected area, allow to work for 15 minutes, then blot up stain with a clean cloth.
  • ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
  • TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works!
  • SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets and in your home.
No. 12
AmazonCommercial Multi-Purpose Enzyme Cleaner, Mint, 1 Gallon, 128 Fl Oz (Pack of 1)
  • 1 gallon bottle of multi-purpose enzyme cleaning solution for a wide variety of surfaces and environments – use on carpets, furniture, hardwood, tile, drains, liter boxes, garbage cans, RVs and more
  • Breaks up complex organic proteins, pet smells and stains, grease, oils, and more for effective results
  • Powerful enzymatic formula removes stains and odors deep in the carpet
  • Attack grease, fats and other organic matter that cause slow drains and unpleasant odors - not a hazardous, caustic drain opener effective on bathroom clogs from hair
  • Non-corrosive, non-flammable, non-acidic, and non-caustic with a fresh mint scent
No. 13
Simple Solution Extreme Pet Stain And Odor Remover, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power, 32 Ounces
  • MADE FOR TOUGH ODORS AND ORGANIC STAINS - Simple Solution Extreme Stain and Odor remover is three times stronger than our regular formula to eliminate tough to clean pet stains.
  • PROFESSIONAL STRENGTH FORMULA - Extreme Stain and Odor Remover is a professional strength Pro-Bacteria and enzyme formula that breaks down and eliminates both new and old stains and odors.
  • SPECIFICALLY FOR DOG AND CAT ODORS AND STAINS - Safely and quickly removes dog and cat urine, feces, and vomit on carpet, upholstery, bedding, fabric toys, clothing, or other water-safe surfaces in your home.
  • PATENTED MULTI-FUNCTIONAL SPRAYER - Now designed with a new patented 3-in-1 nozzle sprayer (foam, mist, and stream).
No. 14
Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies
  • DUAL ACTION - Our stain remover and pet odor eliminator for home will help you enjoy having your furry friends around without the messes! Our enzyme-active pet carpet cleaner tackles stains, smells, and even pet urine, feces and vomit.
  • DESTROY STAINS AND SMELLS - This extremely effective dog urine odor eliminator spray doesn't just mask foul odors and stains, it destroys them upon contact to ensure up to 80 hours of freshness.
  • MULTI-SURFACE USE - A versatile odor eliminator and carpet stain remover that can clean it all! This multi-surface enzyme cleaner for dog urine works great on most surfaces, from carpet to hardwood floors, fabric, turf, and more.
  • CITRUS SCENT - Made from citrus enzymes and cold-pressed orange oils, this pet stain and odor remover leaves a fruity fragrance behind with every spritz! Safe for both pets and children. (Do not spray directly onto either, though.)
  • CUSTOMER SATISFACTION - Add this enzymatic cleaner to the top of your list of pet supplies for dogs and puppies. If you have any questions or concerns about your purchase, reach out to our support team.
SaleNo. 15
Nature's Miracle Advanced Stain and Odor Eliminator Foam Cat 17.5 Ounces, for Severe Cat Messes, Aerosol
  • FOR SEVERE CAT MESSES: Powerful enzymatic formula works to eliminate tough stains and odors from cat urine, diarrhea, vomit and other bio-based accidents
  • FOAMING AEROSOL: Penetrates down into carpet to power out severe cat messes such as, urine, feces and vomit
  • TARGETS PET ODORS: Includes patented microbes that target tough pet odors
  • DISCOURAGES RE-SOILING: Removes the odor from even the toughest cat messes
  • TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works
SaleNo. 16
Nature's Miracle Advanced Cat Stain and Odor Eliminator Spray, Severe Mess Enzymatic Formula, 32 fl oz
12,672 Consomer Reviews
Nature's Miracle Advanced Cat Stain and Odor Eliminator Spray, Severe Mess Enzymatic Formula, 32 fl oz
  • FOR SEVERE CAT MESSES: Powerful enzymatic formula works to eliminate tough stains and odors from cat urine, diarrhea, vomit and other bio-based accidents.
  • LIGHT FRESH SCENT: Cat odor control formula gets your home smelling clean again.
  • ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
  • DISCOURAGES RESOILING: Removes the odor from even the toughest cat messes.
  • TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works!
  • SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets.
SaleNo. 17
Nature's Miracle Stain and Odor Remover Cat, Odor Control Formula, Pour
  • TOUGH ON STAINS AND ODORS: This stain and odor remover is tough on cat urine, feces, vomit, drool and other organic stains and odors.
  • MULTI-SURFACE USE: When used and stored as directed, this product is safe for use on carpets, hard floors, furniture, fabrics and more.
  • SAFE FOR PETS AND HOME: We’ve been loved by pet parents for over 35 years, so we know the importance of having effective stain and odor remover that, when used and stored as directed, is safe to use around pets.
  • CITRUS SCENT: In addition to removing stains and odors, this product freshens with a light citrus scent.
  • TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works.
No. 18
Nature's Miracle Cat & Dog Urine Destroyer Foam Aerosol Sprays 17.5 oz
  • Nature'S Miracle Nm Cat Urine Destroyer Foam, 17.5 Oz Can
SaleNo. 19
Nature's Miracle Hard Floor Cleaner, Dual-Action Stain & Odor Remover, Protects Natural Floor Finishes, 24 oz
  • STAIN AND ODOR REMOVER: This product is ideal for removing stains and odors caused by urine, fecal matter, grease, oil, fats and other organic substrates
  • USE AREAS: Nature’s Miracle Hard Floor Cleaner safely works to remove new and deep-set stains and odors from sealed wood, linoleum, vinyl, concrete & ceramic tile
  • PROTECTS NATURAL FLOOR FINISH: The bio-enzymatic formula cleans deeply while protecting the natural floor finish
  • Effective stain and odor remover that, when used and stored as directed, is safe to use around pets
  • We’re sure you’re going to be very happy and mess free
SaleNo. 20
Nature's Miracle Stain and Odor Remover, Spot Stain and Pet Odor Eliminator, Enzymatic Formula, 32 Ounce Spray
  • SPOT STAIN & ODOR REMOVER: Begins to break down and remove cat stains immediately on contact.
  • LIGHT CITRUS SCENT: Cat odor control formula gets your home smelling clean again.
  • ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
  • TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works.
  • SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets.

How to choose a good cat urine enzymatic cleaner

Does the idea of finding a fantastic cat urine enzymatic cleaner make you anxious? When it comes to purchasing this product, specifically when deciding which model to select, has your head been spinning between options? You are not alone if that is the case. We are aware of the pressure involved in the purchasing process!

Your presence here indicates that you are interested in cat urine enzymatic cleaner. Before choosing which product would be the best for your needs after being inundated with information, locate a reliable source with genuine selections. You can get that information from a variety of sources, including buying guides and rating websites, word-of-mouth recommendations from friends and family, online discussion forums where users can share their own experiences, product reviews that can be found all over the internet, and YouTube channels. You can only get the right product through exhaustive analysis. But you realize that’s not always simple. In order to ease your concerns, we have taken the time to develop a list of the top cat urine enzymatic cleaner products available right now. You might be wondering how we came up with the list. How was this buying guide developed?

First, we used our algorithms to gather as much reliable data as we could about these products. To verify all the data gathered, we used both artificial intelligence and a lot of algorithms.
Then, our experts used criteria that are recognized in the business to evaluate them according to their quality to price ratio, allowing us to choose the top cat urine enzymatic cleaner on the market right now!

The selection of the goods is not arbitrary. Before creating a list, we take into account a number of factors. Below are some of the criteria discussed:

Brand Value: What happens if you choose a dubious brand just because it appears to be a good deal? So the likelihood of receiving a product with a short shelf life increases. That is due to the fact that well-known brands have a reputation to uphold, while others do not. Top cat urine enzymatic cleaner brands strive to provide some distinctive traits that set them apart from the competition. So, hopefully one or more of the items on our list will be perfect for you.

Features: Useful features are all you need, not tons of them. We consider the important aspects and select the top cat urine enzymatic cleaner based on those.

Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products with higher specifications, but with the right balance.

Quality: A product’s quality may always be quantified with the aid of numbers. We look for goods with better standards that strike the proper balance. The best quality product that gets highly appreciated and recommended by experienced users.

Customer ratings:  Would it be accurate to suggest that the cat urine enzymatic cleaner were used by hundreds of customers before you? Superior ratings indicate that many customers had better service.

Customer Reviews: Like ratings,  provide you with accurate and reliable information about the product from genuine customers. Customer ratings are very important to all of us because they contain accurate and reliable information about the customer service we received from several hundred customers.

Seller Rank: This is very intriguing! Not only do you need a good cat urine enzymatic cleaner, you also need a product with rising sales that is trendy. It accomplishes two goals. First, the expanding user base proves the quality of the product. Second, given that number, producers must be able to offer greater quality and after-sales support.

Value: You get what you pay for, they say, so consider the value. Cheap isn’t always good and expensive isn’t always bad. However, that does not imply that spending a lot of money on a product that is flashy but underwhelming is a good idea. Before adding them to the list, we make an effort to evaluate how much value you can get for your money from your cat urine enzymatic cleaner.

Durability: Durability and reliability are closely related concepts. You will benefit from a strong and long-lasting cat urine enzymatic cleaner for months and years to come.

Product availability: Products come and go, and new ones replace the old ones. Most likely, a few new features and required changes were made. What use is it to use a supposedly good product if the maker no longer supports it? We make an effort to highlight products that are current and offered by one or more trustworthy sellers, if not more.

Negative Reviews: Yes, we do take that into account as well! The goods with the majority of bad reviews are filtered out and disregarded when we choose the best-rated one on the market.

These are the standards by which we selected our cat urine enzymatic cleaner. Do we end our process there? Hell no. The most crucial fact about us that you should be aware of is that we regularly update our website with current and pertinent information. We have one more layer of filtration since we place the greatest importance on reader satisfaction. Please let us know if any product included here is incorrect, irrelevant, subpar, or simply out of date. We always value your opinions, and we’ll work hard to make any necessary corrections to our list in response to them.

Why should you believe us?

There are now thousands of possibilities for these products on Amazon, but choosing the best one can be difficult and time-consuming. And what cat urine enzymatic cleaner should you purchase in 2022?

This guide is the result of more than 10 years of experience in researching, testing and writing about many topics. Each member of our team is an authority in their area. We read every article we could find online and every consumer review on every retail website for seven hours. Additionally, we discovered a ton of websites that offered helpful resources, including buying tips and thorough information on cat urine enzymatic cleaner.