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The 8 Best chemical drain openers of 2025

Are you trying to find chemical drain openers among various brands on the market but aren’t sure where to begin? To assist you in finding the right one, we’ve put together a list of the 7 best to help you pick the perfect one!

We investigated and evaluated a number of the top-selling chemical drain openers on the market in order to create our list of the best. Making a decision among the many options available is never simple. There are an infinite number of models available, each with a distinct price. And as you’ll find out, the best options aren’t usually the ones you imagine! This comparison is rich and relevant because of the numerous factors that were employed. You will find products featured in this ranking not only based on their pricing but also on their features and other customers reviews. To write this review, we completed 16 hours of research and did 38 chemical drain openers tests. You won’t need to pick products at random any more. If you’re unsure of what to look for, browse our list and consult the buying guide!

An overview of our top picks

Table of contents

The best chemical drain openers you can buy today

SaleNo. 1
Green Gobbler Enzyme Drain Cleaner | Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps | 1 Gallon
  • ENZYME ENHANCED FORMULA: Green Gobbler Enzymatic Drain & Grease Trap Cleaner uses an enzyme enhanced formula to clear buildup and remove odors in grease traps, septic tanks and similar plumbing systems. It helps digests oils, fats, grease, sludge and other food waste within hours of application. This bottle uses anti-glug technology to help reduce splashing and provides up to eight treatments.
  • SAFE FOR PIPES: Green Gobbler helps maintain drain lines, septic tanks, grease traps and grease interceptors. Our enzyme enhanced formula is an excellent alternative to sodium hydroxide and other caustic chemicals.
  • IMPROVE GREASE TRAP EFFICIENCY: Green Gobbler increases the efficacy of grease traps by allowing enzymes & bacteria to work more efficiently to promote the separation of water and grease, helping your trap run more smoothly.
  • KEEP SEPTIC TANKS HEALTHY: Green Gobbler helps prompt the biological breakdown of foul odors and organic material inside demanding environments such as drains, pipes and septic tanks.
  • GREEN GOBBLER GUARANTEE: Green Gobbler cares about its customers. We take pride in developing innovative & effective products for your home or business. If for any reason you are unsatisfied, please contact us. We offer a money-back guarantee within 30 days of purchase.
SaleNo. 2
Green Gobbler Liquid Hair Drain Clog Remover & Cleaner, For Toilets, Sinks, Tubs - Septic Safe, 2 Pack
28,040 Consomer Reviews
Green Gobbler Liquid Hair Drain Clog Remover & Cleaner, For Toilets, Sinks, Tubs - Septic Safe, 2 Pack
  • "DISSOLVES HAIR, SOAP, TOILET PAPER, GREASE & FLUSHABLE PERSONAL CARE WIPES: Forget the dirty work of plunging clogged toilets and backed-up drains. Green Gobbler sinks through standing water to clear clogs and keep your plumbing flowing properly. It dissolves hair, soap scum, toilet paper, flushable wipes and organic matter. "
  • EASY TO USE PACKAGING, POWERFUL AND EFFECTIVE FORMULA: This drain and pipe cleaner is a simple and highly effective way to eliminate clogs. The extra wide bottle opening helps reduce splashing and our clear side view strip makes it easy to control each application – no need to measure! Each bottle has up to two clog remover treatments.
  • 6-IN-1 SAFE: This drain opener is safe to use in pipes, toilets, sinks, tubs, showers and septic systems. Our formula is non-corrosive to plumbing and dissolves hair more effectively than traditional bleach-based drain openers
  • BLEACH FREE FORMULA: Odorless and free of fumes, it's safe for PVC, ABS, copper and cast iron household pipes. The formula doesn't contain bleach, lye of VOC's.
  • GREEN GOBBLER GUARANTEE: Green Gobbler cares about its customers. We take pride in developing innovative & effective products for your home or business. If for any reason you are unsatisfied, please contact us. We offer a money-back guarantee within 30 days of purchase.
SaleNo. 3
Drano Max Build Up Remover Drain Clog Remover and Cleaner, Great for Clog Prevention, Commercial Line, 60 oz
  • TRUSTED BRAND: Drano has been used and trusted for generations. Avoid spending money on a plumber, and use Drano once a month for drain maintenance and clog prevention.
  • UNIQUE FORMULA: Drano Max Build Up Remover uses a unique formula with natural enzymes and probiotics, that eat through gunk. Free of bleach. Contains a clean, citrus fragrance.
  • PREVENTS CLOGS: Will not open clogs. Use it once a month to keep your drains running smoothly and prevent clogged drains. An ounce of prevention is worth a pound of cure!
  • SAFE ON PIPES: Safe for bathroom and kitchen sinks as well as toilets.
  • WORKS OVERNIGHT: Can leave in drains overnight. For tough clogs, leave Drano in your drain overnight to fully break down the clog before flushing with hot water.
No. 4
Drano Balance Drain Clog Remover and Cleaner, Non-Corrosive Formula, Safe on All Pipes and Septic Tanks, Formulated Using Only Essential Ingredients, 32 Fl Oz
  • SAFE ON PIPES: Drain cleaner that's safe for use on all pipes; great for drains and sinks. Formulated with only essential ingredients needed to break down clogs, this liquid Drano is non-corrosive to pipes and has no harsh smell.
  • LESS MESS THAN HOME REMEDIES: Use Drano Balance instead of home remedies such as drain snakes, plungers, and baking soda for tidier results while still keeping your drains safe from corrosive ingredients.
  • DRAIN MAINTENANCE: Works great for drain maintenance and clog prevention. Use Drano Balance regularly to prevent build-up before a clog occurs.
  • EASY TO USE: Quick and easy to use drain clog remover: pour in, leave for 45-60 mins, and flush with hot water.
  • TRUSTED BRAND: Drano has been used and trusted for generations. Avoid spending money on a plumber, and use Drano once a month for drain maintenance and clog prevention.
No. 5
Green Gobbler Drain Clog Remover & Drain Cleaner Powder | 20+ Treatments | Drain Maintenance Breaks Down Grease, Paper, Fat & Oil | Septic Safe
  • ELIMINATE 20+ DRAIN CLOGS: Break up the toughest clogs with Green Gobbler Drain Opening Powder. You don't need to guess how much product to use; simply add 1 scoop of powder to your clogged drain and let it sit for 15-30 minutes before flushing with hot water. That's it.
  • EFFECTIVE AGAINST: Hair, soap scum, toilet paper, organic materials, and flushable hygiene products. Clear your clogs and keep your plumbing flowing properly
  • WORKS GREAT ON: Bathroom sinks, bathtubs, showers, toilets, kitchen sinks, floor drains, slop sinks, septic tanks, urinals and more.
  • BLEACH FREE FORMULA: Our product does not contain any bleach or sodium hydroxide and is safe for pipes, septic systems, and toilets.
No. 6
Amazon Basics Max Strength Gel Drain Clog Remover and Cleaner, Unclogs Hair and Grease, 80 Fl Oz, Pack of 1
  • 1 bottle of Max Strength Gel Formula Drain Clog Remover
  • Guaranteed lab tested drain opening performance ***For best results ensure product is at room temperature***
  • Clears heavy clogs dissolving hair, grease and gunk so drains flow freely again ***NOT INTENDED FOR USE ON CLOGGED TOILETS***
  • Pours through standing water and starts working on contact to cut through blockages and clear drains ***Flush with VERY HOT water for best results***
  • Phosphate free formula is safe for use on all pipes, garbage disposals and septic tanks
  • If you like Drano Max Gel Drain Clog Remover, we invite you to try Amazon Basics Max Strength Gel Drain Clog Remover
  • Easy pour “no glug” bottle helps eliminate splashing
  • Product dimensions: 80 fluid ounce bottle, 11 x 5.5 x 4.625 inches (HxWxD)
  • An Amazon Brand
SaleNo. 7
Green Gobbler Ultimate Main Drain Opener | Drain cleaner Hair Clog Remover | Works On Main Lines, Sinks, Tubs, Toilets, Showers, Kitchen Sinks | 64 fl. oz.
  • HIGH-DENSITY MAIN LINE DRAIN OPENER. Ultimate Main Line Opener’s thick, high-density formula sinks through water and clings to pipes to liquify tough drain obstructions, clearing the main line to and from your home.
  • DISSOLVES ORGANIC MATERIAL AND PAPER. Ultimate Main Line Opener dissolves grease, hair, oils, soap scum, baby wipes, and paper products easily.The revolutionary formula is great for both addressing clogs and preventive maintenance.
  • NON-DAMAGING TO PIPES. Green Gobbler’s industrial-strength drain clog remover is tough where it counts. While it takes care of the toughest clogs, it remains gentle on pipes and septic systems.
  • ENVIRONMENTALLY FRIENDLY AND SAFER TO USE. Ultimate Main Line Opener is safer to use than chemical-based cleaners. It’s odorless, non-flammable
  • GREEN GOBBLER GUARANTEE: Green Gobbler cares about its customers. We take pride in developing innovative & effective products for your home or business. We offer a money-back guarantee within 30 days of purchase.
SaleNo. 8
Liquid-Plumr Pro-Strength Clog Destroyer Gel with PipeGuard, Liquid Drain Cleaner - 80 Ounces (Package May Vary)
  • DRAIN CLOG REMOVER: Liquid-Plumr Clog Destroyer Gel with PipeGuard uses 3-in-1 action to dissolve tough clogs, prevent new ones from forming, and remove unpleasant odors; Package may vary
  • WORKS ON MULTIPLE CLOG TYPES: This gel clog remover tackles the toughest clogs from hair, grease, and soap scum and cutes through standing water to cleat total blockages
  • SAFE ON ALL PIPES: Made with Pipeguard, this Liquid-Plumr drain cleaner protects pipes and is safe for septic systems, disposals and pipes, including PVC, plastic, copper and old drain pipes
  • ODOR ELIMINATOR: Pro-Strength drain opener is a drain deodorizer and cleaner and works great on bathtubs, bathroom sinks, showers, kitchen sinks and garbage disposals; Do not use in toilets
  • MAINTAIN CLEAR PIPES & DRAINS: When used monthly, Liquid-Plumr drain clog remover with PipeGuard prevents clogs from coming back
  • This drain cleaner is safe for all septic systems, disposals and pipes, including PVC, plastic, copper and old pipes
SaleNo. 9
Thrift Marketing GIDDS-TY-0400879 Drain Cleaner 2 lb , White
  • This product is highly durable
  • This product adds a great value
  • This product is manufactured in United states
  • THRIFT works on drains, sewer lines, grease traps, and septic systems.
  • THRIFT will clean out a drain line in less than 60 seconds!
  • THRIFT is safe to use on most kitchen or lavatory surfaces.
No. 10
Liquid Fire Drain Line Opener, 32 Oz
  • Liquid Fire provides professional results cleaning drain pipes in sinks, tubs, shower stalls, plus septic tanks and laterals
  • As you Pour Liquid Fire into clogged or slow running drain, it reacts instantly creating heat
  • Provides free running drain in freezing weather by chemically creating heat instantly
  • It works faster and more effectively than most other popular cleaners and is more economical
No. 11
Instant Power Hair and Grease Drain Opener – Multipurpose Liquid Drain Cleaner and Clog Remover, Odorless, Ready to Use, 33.8 Oz, 1 Liter
  • STRONGEST FORMULATION IN THE MARKET: Instant Power's hair and grease drain cleaner is formulated to be 20x stronger than common drain openers; It breaks down drain-clogging matter, clearing the lines without causing harm to the pipes
  • EFFECTIVE AGAINST HAIR & GREASE: Dissolves hair and creates heat to melt grease without using caustic ingredients that can damage your drainage; Eliminate clogs and keep them out with this drain clog remover
  • SAFE AND EASY-TO-USE: Our clogged drain opener uses a non-acid formula, so it's safe on your pipes and septic systems; It's also ready to use, just pour the drain opener slowly, directly into the drain and repeat if necessary
  • TOUGH ON CLOGS NOT ON NOSE: This effective clog remover is made with a non-acid formula designed for the most stubborn drain clogs; It's odorless or does not produce fumes
  • MULTIPURPOSE DRAIN CLEANER: Clears clogged drains and blocked pipes in kitchen sinks, bathrooms tubs and showers, and RV drain systems; Not for use in garbage disposals
SaleNo. 12
Green Gobbler Drain Clog Dissolver, Drain Opener-Cleaner ,Toilet Clog Remover, 31 oz
  • DISSOLVES HAIR, SOAP, TOILET PAPER & FLUSHABLE PERSONAL CARE WIPES: Forget the dirty work of plunging clogged toilets and end backed-up drains once and for all! The highly effective formula of Green Gobbler clears clogged drains and dissolves hair, toilet paper, flushable personal care wipes, soap scum and other organic matter that may be causing clogs within your pipes.
  • EASY TO USE PACKAGING, POWERFUL AND EFFECTIVE FORMULA: This drain and pipe cleaner is a simple and highly effective way to eliminate clogs. The extra wide bottle opening helps reduce splashing and our clear side view strip makes it easy to control each application – no need to measure! Each bottle has up to two clog remover treatments.
  • 6-IN-1 SAFE: This drain opener is safe to use in pipes, toilets, sinks, tubs, showers and septic systems. Our formula is non-corrosive to plumbing and dissolves hair more effectivley than traditional bleach-based drain openers
  • BLEACH FREE FORMULA: Odorless and free of fumes, it's safe for PVC, ABS, copper and cast iron household pipes. The formula doesn't contain bleach, lye of VOC's.
  • GREEN GOBBLER GUARANTEE: Green Gobbler cares about its customers. We take pride in developing innovative & effective products for your home or business. If for any reason you are unsatisfied, please contact us. We offer a money-back guarantee within 30 days of purchase.
No. 13
Zep Drain Defense Pipe Build-Up Remover - 64 Ounces - ZLDC648 - Professional Strength Liquid Pipe Build Up Remover,GREEN
  • For use in: sinks, garbage disposals, tub/shower drains, RVs and grease traps
  • ENZYME BASED FORMULA: Breaks down drain-clogging elements
  • SAFE FOR: PVC and most other septic systems. Use monthly to prevent clogs, slow drains & restore flow
  • BREAKS DOWN: Into CO2, minerals and water
  • Enzymes remove years of build-up. Provides 21 months of drain protection
SaleNo. 14
Liquid-Plumr Pro-Strength Clog Destroyer Gel with PipeGuard, Liquid Drain Cleaner - 32 Ounces (Package May Vary)
  • DRAIN CLOG REMOVER: Liquid-Plumr Clog Destroyer Gel with PipeGuard uses 3-in-1 action to dissolve tough clogs, prevent new ones from forming, and remove unpleasant odors; Package may vary
  • WORKS ON MULTIPLE CLOG TYPES: This gel clog remover tackles the toughest clogs from hair, grease, and soap scum and cutes through standing water to cleat total blockages
  • SAFE ON ALL PIPES: Made with Pipeguard, this Liquid-Plumr drain cleaner protects pipes and is safe for septic systems, disposals and pipes, including PVC, plastic, copper and old drain pipes
  • ODOR ELIMINATOR: Pro-Strength drain opener is a drain deodorizer and cleaner and works great on bathtubs, bathroom sinks, showers, kitchen sinks and garbage disposals; Do not use in toilets
  • MAINTAIN CLEAR PIPES & DRAINS: When used monthly, Liquid-Plumr drain clog remover with PipeGuard prevents clogs from coming back
  • This drain cleaner is safe for all septic systems, disposals and pipes, including PVC, plastic, copper and old pipes
SaleNo. 15
Instant Power Hair & Grease Drain Opener 2 L
  • This unique formulation dissolves hair clogs from bathroom drains and creates heat to melt grease from kitchen sinks. DISSOLVES HAIR CLOGS CREATES HEAT TO MELT GREASE Packaging may contain one-2 liter container or two-1 liter containters
SaleNo. 16
Zep Advanced Bathroom Sink Drain Opener Gel - 32 Ounce - U49310 - Formulated for Toothpaste, Shave Cream, Hair, Soap and Makeup
  • WORKS IN STANDING WATER: Targeted attack Advanced Bathroom Sink Drain Opener Gel is specially formulated to clear bathroom sink clogs quickly
  • SPECIALTY FORMULA: Uniquely designed for bathroom sinks
  • Uniquely designed for bathroom sinks
  • SPECIALTY DESIGNED FOR BATHROOM SINKS: Dissolves toothpaste, shave cream, hair, makeup and soap scum from bathroom sinks
  • Not for use in toilets or garbage disposals
No. 17
TY-0400879 Drain Cleaner 2 lb (2-(Pack))_AB
  • This product is highly durable
  • This product adds a great value
  • This product is manufactured in United states Key Product Features
  • THRIFT works on drains, sewer lines, grease traps, and septic systems.
  • THRIFT will clean out a drain line in less than 60 seconds!
No. 18
ComStar Pure Lye | 99% Pure Sodium Hydroxide Beads | Eco-Friendly, Industrial Strength, Biodegradable Drain Opener | Safe on Fixtures | Static-Free, Unique Beads for Soap Making | 1 lb. (30-500)
  • ComStar Pure Lye is an industrial-strength, eco-friendly, 99% pure Sodium Hydroxide bead formula. It's designed to clear out drains, grease traps, and septic systems by dissolving grease, hair and root growth instantly. ComStar Pure Lye is also a best-selling soap maker!
  • This sodium hydroxide formula is the purest white, bead-size lye in the world—99% pure. A natural drain opener, its non-acid, biodegradable formula is safe on fine fixtures, chrome trim, and metal or plastic pipes, if used as directed.
  • This fantastic product clears clogged and slow-moving drains, grease traps, and septic systems without harming septic or cesspools. Applied regularly, it enhances the growth of active bacteria. Because of its unique bead shape, ComStar Pure Lye will sink to the bottom of standing water and attack the cause of the blockage for a fast break-up.
  • ComStar Pure Lye does not stink or create fumes and has become a favorite drain-opening product for homes, schools, hospitals, cafeterias, and restaurants.
  • Crafters prefer ComStar Pure Lye’s small beads for soap making because they do not clump together, create static, and dissolve quickly. As a result, soap making is faster and easier with ComStar Pure Lye.

How to choose a good chemical drain openers

Does the idea of finding a fantastic chemical drain openers make you anxious? When it comes to purchasing this product, specifically when deciding which model to select, has your head been spinning between options? You are not alone if that is the case. We are aware of the pressure involved in the purchasing process!

Your presence here indicates that you are interested in chemical drain openers. Before choosing which product would be the best for your needs after being inundated with information, locate a reliable source with genuine selections. You can get that information from a variety of sources, including buying guides and rating websites, word-of-mouth recommendations from friends and family, online discussion forums where users can share their own experiences, product reviews that can be found all over the internet, and YouTube channels. You can only get the right product through exhaustive analysis. But you realize that’s not always simple. In order to ease your concerns, we have taken the time to develop a list of the top chemical drain openers products available right now. You might be wondering how we came up with the list. How was this buying guide developed?

First, we used our algorithms to gather as much reliable data as we could about these products. To verify all the data gathered, we used both artificial intelligence and a lot of algorithms.
Then, our experts used criteria that are recognized in the business to evaluate them according to their quality to price ratio, allowing us to choose the top chemical drain openers on the market right now!

The selection of the goods is not arbitrary. Before creating a list, we take into account a number of factors. Below are some of the criteria discussed:

Brand Value: What happens if you choose a dubious brand just because it appears to be a good deal? So the likelihood of receiving a product with a short shelf life increases. That is due to the fact that well-known brands have a reputation to uphold, while others do not. Top chemical drain openers brands strive to provide some distinctive traits that set them apart from the competition. So, hopefully one or more of the items on our list will be perfect for you.

Features: Useful features are all you need, not tons of them. We consider the important aspects and select the top chemical drain openers based on those.

Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products with higher specifications, but with the right balance.

Quality: A product’s quality may always be quantified with the aid of numbers. We look for goods with better standards that strike the proper balance. The best quality product that gets highly appreciated and recommended by experienced users.

Customer ratings:  Would it be accurate to suggest that the chemical drain openers were used by hundreds of customers before you? Superior ratings indicate that many customers had better service.

Customer Reviews: Like ratings,  provide you with accurate and reliable information about the product from genuine customers. Customer ratings are very important to all of us because they contain accurate and reliable information about the customer service we received from several hundred customers.

Seller Rank: This is very intriguing! Not only do you need a good chemical drain openers, you also need a product with rising sales that is trendy. It accomplishes two goals. First, the expanding user base proves the quality of the product. Second, given that number, producers must be able to offer greater quality and after-sales support.

Value: You get what you pay for, they say, so consider the value. Cheap isn’t always good and expensive isn’t always bad. However, that does not imply that spending a lot of money on a product that is flashy but underwhelming is a good idea. Before adding them to the list, we make an effort to evaluate how much value you can get for your money from your chemical drain openers.

Durability: Durability and reliability are closely related concepts. You will benefit from a strong and long-lasting chemical drain openers for months and years to come.

Product availability: Products come and go, and new ones replace the old ones. Most likely, a few new features and required changes were made. What use is it to use a supposedly good product if the maker no longer supports it? We make an effort to highlight products that are current and offered by one or more trustworthy sellers, if not more.

Negative Reviews: Yes, we do take that into account as well! The goods with the majority of bad reviews are filtered out and disregarded when we choose the best-rated one on the market.

These are the standards by which we selected our chemical drain openers. Do we end our process there? Hell no. The most crucial fact about us that you should be aware of is that we regularly update our website with current and pertinent information. We have one more layer of filtration since we place the greatest importance on reader satisfaction. Please let us know if any product included here is incorrect, irrelevant, subpar, or simply out of date. We always value your opinions, and we’ll work hard to make any necessary corrections to our list in response to them.

Why should you believe us?

There are now thousands of possibilities for these products on Amazon, but choosing the best one can be difficult and time-consuming. And what chemical drain openers should you purchase in 2022?

This guide is the result of more than 10 years of experience in researching, testing and writing about many topics. Each member of our team is an authority in their area. We read every article we could find online and every consumer review on every retail website for seven hours. Additionally, we discovered a ton of websites that offered helpful resources, including buying tips and thorough information on chemical drain openers.