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The 8 Best decongestant nasal sprays of 2024

Are you trying to find decongestant nasal sprays among various brands on the market but aren’t sure where to begin? To assist you in finding the right one, we’ve put together a list of the 7 best to help you pick the perfect one!

We investigated and evaluated a number of the top-selling decongestant nasal sprays on the market in order to create our list of the best. Making a decision among the many options available is never simple. There are an infinite number of models available, each with a distinct price. And as you’ll find out, the best options aren’t usually the ones you imagine! This comparison is rich and relevant because of the numerous factors that were employed. You will find products featured in this ranking not only based on their pricing but also on their features and other customers reviews. To write this review, we completed 24 hours of research and did 43 decongestant nasal sprays tests. You won’t need to pick products at random any more. If you’re unsure of what to look for, browse our list and consult the buying guide!

An overview of our top picks

Table of contents

The best decongestant nasal sprays you can buy today

No. 1
Amazon Basic Care No Drip Nasal Spray, 12 Hour Nasal Decongestant, Pump Mist, Oxymetazoline HCl, Cold and Allergy Nasal Spray, 1 Fl Oz (Pack of 1)
  • ACTIVE INGREDIENT: This nasal spray contains oxymetazoline HCl, the #1 doctor recommended adult nasal spray active ingredient (of U.S. physicians surveyed by an independent market research firm). Compare to the active ingredient in Afrin No Drip.
  • SOOTHING 12 HOUR MAXIMUM STRENGTH RELIEF: Amazon Basic Care No Drip Nasal Spray, Oxymetazoline HCl provides 12 hours of maximum strength nasal congestion relief due to the common cold, hay fever and upper respiratory allergies.
  • FAST NASAL CONGESTION RELIEF: Amazon Basic Care No Drip Nasal Spray, Oxymetazoline HCl provides fast and powerful relief for colds and allergies. Temporarily relieves sinus congestion and pressure.
  • NASAL RELIEF: Amazon Basic Care No Drip Nasal Spray, Oxymetazoline HCl provides temporary nasal congestion relief by shrinking swollen nasal membranes so you can breathe more freely.
  • NO DRIP NASAL SPRAY: This cold and allergy relief nasal spray won't drip down your nose or throat. Nasal decongestant pump mist. This product is gluten free.
SaleNo. 2
Vicks Sinex SEVERE Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Stuffy Nose due to Cold or Allergy, & Nasal Congestion, Sinus Pressure Relief, 265 Sprays x 2
  • Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
  • Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
  • This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
  • Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
  • Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details
SaleNo. 3
Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL
  • Afrin No Drip Extra Moisturizing is a nasal pump mist designed to relieve nasal congestion for up to 12 hours
  • Nasal decongestant pump mist works instantly to provide nasal and sinus congestion relief caused by allergies or other nasal irritants.
  • Medicated no drip nasal spray doesn’t drip from your nose or down your throat
  • 12 hour medicated moisturizing nasal spray soothes dry nasal passages
  • Use Afrin nasal mist as directed, spraying two or three times into each nostril for no more than three days
No. 5
Amazon Basic Care Nasal Four Nasal Spray, Phenylephrine Hydrochloride 1 Percent, Nasal Decongestant, 1 Fl Oz (Pack of 1)
  • ACTIVE INGREDIENT: Amazon Basic Care Nasal Four Nasal Spray contains phenylephrine hydrochloride 1%, a nasal decongestant, which compares to the active ingredient in 4-Way.
  • FAST-ACTING NASAL SPRAY: Amazon Basic Care Nasal Four Nasal Spray contains a nasal decongestant that delivers fast relief of nasal congestion for up to four hours.
  • MULTI-SYMPTOM RELIEF: Amazon Basic Care Nasal Four Nasal Spray relieves nasal congestion, swollen nasal membranes, sinus congestion and sinus pressure.
  • NON-DROWSY NASAL CONGESTION RELIEF: Amazon Basic Care Nasal Four Nasal Spray provides non-drowsy relief for nasal symptoms so that you can get through your day.
  • FOR AGES 12 YEARS AND OLDER: Amazon Basic Care Nasal Four Nasal Spray provides fast nasal congestion relief for adults and children ages 12 years and older.
No. 7
Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
  • Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
  • Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
  • This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
  • Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
  • Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details
No. 8
Afrin No Drip Severe Congestion Maximum Strength Nasal Spray - 12 Hour Nasal Spray Relief for Nose Congestion, Nasal Swelling, and Allergies - 2 x 0.5 Fl Oz Bottles - Pack of 1
  • One two-pack box of 15 mL Afrin No Drip Severe Congestion Maximum Strength 12 Hour Nasal Congestion Relief Spray
  • Maximum strength nasal spray with menthol for instant nasal and sinus congestion relief
  • No drip sinus spray allows easier breathing through the nose without dripping down your nose or throat. Health Concern: Nasal Congestion Allergy
  • 12 hour nose decongestant provides severe nasal congestion allergy relief
  • Easy-to-use Afrin nasal decongestion pump mist form delivers instant relief
  • HSA/FSA Eligible -- Check your plan for coverage.
SaleNo. 9
GoodSense Maximum Strength Nasal Spray, Fast Powerful Congestion Relief For Colds and Allergies, 1 Fluid Ounce
  • ACTIVE INGREDIENT: This nasal spray contains oxymetazoline hydrochloride 0.05%, a nasal decongestant. Compare to the active ingredient in Afrin Original
  • PURPOSE: This nasal spray temporarily relieves nasal congestion, sinus congestion and pressure due to the common cold, hay fever and upper respiratory allergies
  • 12 HOUR RELIEF: GoodSense Maximum Strength Nasal Spray provides fast, powerful congestion relief for allergies and colds for up to 12 hours
  • FAST CONGESTION RELIEF: Provides fast and powerful nasal congestion relief for allergies and colds
  • FAST-ACTING NASAL DECONGESTANT clears stuffy nose due to upper respiratory allergies and the common cold
SaleNo. 10
SaleNo. 12
Dristan 12-Hour Nasal Spray Decongestant, Fast-Acting Sinus and Nasal Congestion Relief from Colds, Hay Fever and Allergies, Oxymetazoline HCI, 0.5 Fl Oz
  • 12-Hour Powerful Relief: Dristan 12-Hour Nasal Spray provides fast-acting, long-lasting, powerful nasal congestion relief from allergies and colds for up to 12 hours
  • Breathe Freely: The active ingredient oxymetazoline HCI 0.05% shrinks swollen membranes to help relieve sinus congestion and pressure, nasal congestion due to colds, hay fever, and other upper respiratory allergies
  • Starts To Work In Seconds: Get the sinus and nasal congestion relief you need at the speed you need it
  • Relief On-The-Go: Dristan’s convenient spray bottle provides easy nasal decongestant relief wherever you go, whenever you need it
  • Trusted For Over 50 Years: Dristan has provided instant sinus and nasal congestion relief since 1966 and is safe for adults and children ages 6-12 when used as directed
SaleNo. 13
Mucinex Sinus-Max Severe Nasal Congestion Relief Sinus & Allergy Nasal Spray, 0.75 Fl Oz
  • SINUS and ALLERGY RELIEF: Mucinex Sinus-Max Severe Nasal Congestion Relief helps relieve nasal congestion, sinus congestion and sinus pressure
  • TRUSTED COLD BRAND: Cold brand doctors trust
  • NASAL DECONGESTANT: Contains Oxymetazoline HCl, a topical nasal decongestant
  • FAST ACTING RELIEF: Targeted Nasal Congestion relief due to allergies
  • DOSING: Offers fast and long-lasting nasal congestion relief up to 12 hours
  • USAGE: Use as directed; For ages 6 plus years
No. 14
Reliable-1 Laboratories Nasal Spray 12 Hour Relief Nasal Decongestant | Rapid and Powerful Sinus Relief Nose Spray | Pump Mist Anti Drip Congestion Relief | Oxymetazoline HCI | 1 Fl Oz, 3-Pack
  • NASAL SPRAY DECONGESTANT offers immediate and effective sinus and allergy relief. Nose spray is a quick and easy OTC method for sinus pressure relief and nasal decongestion.
  • STUFFY NOSE RELIEF Whether it’s cat allergies that have you stuffy, or the common cold, experience powerful and rapid 12 hour relief with Reliable-1’s nose spray.
  • COLD AND ALLERGY RELIEF Compact size of our nasal spray is ideal for taking on the go, so you’ll never be slowed down by the common cold or a sudden allergy attack. Keep the anti drip nose spray in your purse, glove compartment or briefcase for quick and easy access, whenever you need it.
  • NASAL SPRAY ACTIVE INGREDIENT Compare to Active Ingredient in Afrin Original. 2-3 sprays with pump mist sinus spray clears the nasal passages for temporary congestion relief and easier breathing.
  • RELIABLE 1 Reliable 1 Laboratories is an Over the Counter (OTC) and Nutritional Supplement provider with a leadership team holding 100+ years of experience. Providing you with quality products that best address your family’s health is our priority.
SaleNo. 15
FamilyCare Nasal Relief Spray, Pump Mist, Anti-drip, Severe Congestion, (Oxymetazoline HCI) 12 Hours, 3 Pack
  • 12 hour nasal relief
  • severe congestion
  • compare to afrin severe congestion
  • pump mist
  • anti-drip
SaleNo. 17
KIRKLAND SIGNATURE Aller-Flo Fluticasone Propionate (Glucorticoid) 5 Bottles x 120 Metered Sprays 0.54 Fl OZ per Bottle (15.8 mL x 5) 2.70 OZ Total (79 mL Total) 600 Total Sprays Total, 1-Pack
  • Compare to Flonase Allergy Relief Active Ingredient
  • Fluticasone Propionate(Glucocorticoid) 50 mcg.
  • Indoor/Outdoor Allergy Relief
  • Non-Drowsy
  • 5 Bottles, 120 Sprays Each
No. 18
Perrigo 12 Hour Original Nasal Spray 1 Fl Oz. Qty 4 Pack Compare to Afrin
  • Nasal Decongestant Spray: Perrigo Oxymetazoline HCI 0.05% Nasal Decongestant Spray provides effective relief from nasal congestion caused by various conditions such as the common cold, hay fever, and upper respiratory allergies.
  • Powerful Formula: The nasal spray contains a powerful formula that quickly shrinks swollen nasal membranes, allowing for easier and more comfortable breathing.
  • Versatile Relief: Whether it's seasonal allergies or a cold, Perrigo Oxymetazoline HCI Nasal Decongestant Spray offers temporary relief, helping individuals feel better and go about their day more comfortably.
  • Convenient Packaging: Packaged in a convenient 1oz spray bottle, it is easy to carry and use whenever nasal congestion strikes, providing fast and reliable relief.
  • Effective Relief: Provides effective relief from nasal congestion, enabling individuals to breathe more freely and comfortably.
SaleNo. 19
Mucinex Mucinex Severe Nasal Congestion Relief Clear & Cool Nasal Spray, Cooling Menthol Flavor (Pack Of 3), 3/4 Fl Ounce
  • SINUS & ALLERGY RELIEF: Mucinex Sinus-Max Severe Nasal Congestion Relief helps relieve nasal congestion, sinus congestion and sinus pressure
  • # 1 TRUSTED COLD BRAND: #1 Cold brand doctors trust*
  • COOLING MENTHOL BURST: With an instant cooling menthol burst
  • NASAL DECONGESTANT: Contains Oxymetazoline HCl, a topical nasal decongestant
  • FAST ACTING RELIEF: Targeted Nasal Congestion relief
  • DOSING: Offers fast and long-lasting nasal congestion relief up to 12 hours
  • USAGE: Use as directed; For ages 6+ years

How to choose a good decongestant nasal sprays

Does the idea of finding a fantastic decongestant nasal sprays make you anxious? When it comes to purchasing this product, specifically when deciding which model to select, has your head been spinning between options? You are not alone if that is the case. We are aware of the pressure involved in the purchasing process!

Your presence here indicates that you are interested in decongestant nasal sprays. Before choosing which product would be the best for your needs after being inundated with information, locate a reliable source with genuine selections. You can get that information from a variety of sources, including buying guides and rating websites, word-of-mouth recommendations from friends and family, online discussion forums where users can share their own experiences, product reviews that can be found all over the internet, and YouTube channels. You can only get the right product through exhaustive analysis. But you realize that’s not always simple. In order to ease your concerns, we have taken the time to develop a list of the top decongestant nasal sprays products available right now. You might be wondering how we came up with the list. How was this buying guide developed?

First, we used our algorithms to gather as much reliable data as we could about these products. To verify all the data gathered, we used both artificial intelligence and a lot of algorithms.
Then, our experts used criteria that are recognized in the business to evaluate them according to their quality to price ratio, allowing us to choose the top decongestant nasal sprays on the market right now!

The selection of the goods is not arbitrary. Before creating a list, we take into account a number of factors. Below are some of the criteria discussed:

Brand Value: What happens if you choose a dubious brand just because it appears to be a good deal? So the likelihood of receiving a product with a short shelf life increases. That is due to the fact that well-known brands have a reputation to uphold, while others do not. Top decongestant nasal sprays brands strive to provide some distinctive traits that set them apart from the competition. So, hopefully one or more of the items on our list will be perfect for you.

Features: Useful features are all you need, not tons of them. We consider the important aspects and select the top decongestant nasal sprays based on those.

Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products with higher specifications, but with the right balance.

Quality: A product’s quality may always be quantified with the aid of numbers. We look for goods with better standards that strike the proper balance. The best quality product that gets highly appreciated and recommended by experienced users.

Customer ratings:  Would it be accurate to suggest that the decongestant nasal sprays were used by hundreds of customers before you? Superior ratings indicate that many customers had better service.

Customer Reviews: Like ratings,  provide you with accurate and reliable information about the product from genuine customers. Customer ratings are very important to all of us because they contain accurate and reliable information about the customer service we received from several hundred customers.

Seller Rank: This is very intriguing! Not only do you need a good decongestant nasal sprays, you also need a product with rising sales that is trendy. It accomplishes two goals. First, the expanding user base proves the quality of the product. Second, given that number, producers must be able to offer greater quality and after-sales support.

Value: You get what you pay for, they say, so consider the value. Cheap isn’t always good and expensive isn’t always bad. However, that does not imply that spending a lot of money on a product that is flashy but underwhelming is a good idea. Before adding them to the list, we make an effort to evaluate how much value you can get for your money from your decongestant nasal sprays.

Durability: Durability and reliability are closely related concepts. You will benefit from a strong and long-lasting decongestant nasal sprays for months and years to come.

Product availability: Products come and go, and new ones replace the old ones. Most likely, a few new features and required changes were made. What use is it to use a supposedly good product if the maker no longer supports it? We make an effort to highlight products that are current and offered by one or more trustworthy sellers, if not more.

Negative Reviews: Yes, we do take that into account as well! The goods with the majority of bad reviews are filtered out and disregarded when we choose the best-rated one on the market.

These are the standards by which we selected our decongestant nasal sprays. Do we end our process there? Hell no. The most crucial fact about us that you should be aware of is that we regularly update our website with current and pertinent information. We have one more layer of filtration since we place the greatest importance on reader satisfaction. Please let us know if any product included here is incorrect, irrelevant, subpar, or simply out of date. We always value your opinions, and we’ll work hard to make any necessary corrections to our list in response to them.

Why should you believe us?

There are now thousands of possibilities for these products on Amazon, but choosing the best one can be difficult and time-consuming. And what decongestant nasal sprays should you purchase in 2022?

This guide is the result of more than 10 years of experience in researching, testing and writing about many topics. Each member of our team is an authority in their area. We read every article we could find online and every consumer review on every retail website for seven hours. Additionally, we discovered a ton of websites that offered helpful resources, including buying tips and thorough information on decongestant nasal sprays.