Are you trying to find digestive enzymes among various brands on the market but aren’t sure where to begin? To assist you in finding the right one, we’ve put together a list of the 7 best to help you pick the perfect one!
We investigated and evaluated a number of the top-selling digestive enzymes on the market in order to create our list of the best. Making a decision among the many options available is never simple. There are an infinite number of models available, each with a distinct price. And as you’ll find out, the best options aren’t usually the ones you imagine! This comparison is rich and relevant because of the numerous factors that were employed. You will find products featured in this ranking not only based on their pricing but also on their features and other customers reviews. To write this review, we completed 26 hours of research and did 40 digestive enzymes tests. You won’t need to pick products at random any more. If you’re unsure of what to look for, browse our list and consult the buying guide!
An overview of our top picks
Table of contents
The best digestive enzymes you can buy today
- CONTAINS ALL 10 MOST ESSENTIAL DIGESTIVE ENZYMES: No other digestive enzyme blend contains all 10 most essential digestive enzymes including Amylase, Lipase, Bromelain, Lactase, Papain, Protease, Cellulase, Maltase, Invertase, and Glucoamylase
- TOP 3 PANCREATIC ENZYMES INCLUDED: The Amylase pancreatic enzyme breaks down starches and carbohydrates into sugars. The Lipase enzyme breaks down fats and oils, into glycerol and fatty acids. Lastly, the Protease enzymes break down proteins into amino acids
- VITAZYME DIGESTIVE AID: Double Wood's trademarked digestive enzyme supplement aids digestion and supports overall digestive health. Delivering super enzymes to help with bloating relief
- BREAKDOWN PROTEIN, FATS, AND CARBOHYDRATES: Double Wood's Vitazyme blend contains the most essential digestive and pancreatic enzymes needed to break down fats, proteins, and carbohydrates
- WE BOTTLE WELLNESS: At Double Wood we provide pure, potent supplements that deliver exceptional value, all backed by careful sourcing and rigorous third-party testing
- BREAKS DOWN FATS, CARBS, AND PROTEIN: Super Enzymes is a comprehensive blend of enzymes that supports healthy digestion*
- OPTIMIZES NUTRIENT AVAILABILITY: Formulated with bromelain, ox bile, pancreatin, and papain, Super Enzymes helps to optimize the breakdown of fats, carbohydrates, and protein*
- EASY TO SWALLOW TABLET: Supports healthy digestion!*
- GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation)
- Packaged in the USA by a family owned and operated company since 1968
- Complex containing 9 digestive enzymes per serving (2 capsules) including bromelain and papain, Supports Healthy Digestion*
- Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
- 180 capsules, a 1-3 month supply (taken daily at listed serving size)
- Vegetarian and gluten free
- As a dietary supplement take 2 capsules up to 3 times daily with food; 90 servings per bottle
- Alexa voice shopping enabled: to place your next order, just say, "Alexa, reorder Revly Digestive Enzyme Complex"
- During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
- An Amazon brand
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
- Digestive Enzymes with Pre & Probiotics Supplements: Pre-meal plant-powered pills formulated to help women and men find relief from occasional bloating, gas, and discomfort. AVA-Certified Vegetarian
- Complete Gut Wellness: Replenishes digestive enzymes that may decline with age. Advanced enzyme + prebiotic, probiotic non-GMO formula tackles hard-to-digest foods. For regularity, digestive + immune health. Health Concern: Sensitive Stomach
- Clinically Proven Reliably Alive De111 Probiotic: Guaranteed to arrive alive and work within hours in small intestine where 90% of nutrient absorption occurs + 70% of immune system resides
- Botanical Bounty: Turmeric, Ginger, Green Papaya, Inulin, Apple Pectin, Bladderwrack, Fennel, and Wakame all aid gut health and stomach comfort
- 180 Serving Supply: Includes 1 (180 Count) Zenwise Digestive Enzymes + with Pre & Probiotics. We suggest taking 1 capsule before each meal to experience digestive delight. No refrigeration needed
- ESSENTIAL ENZYMES BENEFITS. Expertly formulated compilation of digestive enzymes that break down multiple food groups: carbohydrates, protein, fat and fiber.
- HOW ESSENTIAL ENZYMES WORK. It aids the body’s natural digestive process and helps maximize the body’s utilization of the nutrients in the diet by helping to break down foods into smaller components that can be absorbed
- SUGGESTED USE: 1 capsule with water at the beginning of each meal (or open capsule and sprinkle over food). Do not sprinkle on hot food. Do not exceed 6 capsules per day.
- OVER 40 YEARS OF TRUST. Source Naturals was created in 1982 by CEO Ira Goldberg to support each individual's potential to enjoy optimal health.
- Manufactured in the USA. Manufactured in Scotts Valley, CA, under the Good Manufacturing Practices (cGMPs) established by the US Food and Drug Administration. (FDA)
- Beat the Bloat & Say Goodbye to Meal Time Discomfort: 16 beneficial enzymes that digest proteins, carbs, fruits, veggies, beans, dairy, & fats to cover all diets. With SBO Probiotics & Prebiotics to aid digestion further - Your New Meal Time Hack! Same great product you love, with a new look. Packaging May Vary!
- Dual Action Relief: Our powerful digestive enzymes aid with breaking down food while the prebiotics & probiotics promote digestive function in the gut. They work synergistically to provide relief from mealtime discomfort.
- Probiotics that Survive the Gut: Formulated with 3 soil-based probiotic strains - specifically selected due to their ability to survive the harsh gut environment. Along with Organic Prebiotics that fuel the growth of healthy bacteria in the gut.
- Science Backed - Our Digestive Enzyme Probiotics are crafted based on scientific research. We have partnered with expert physicians to help review our products & research. We strive to educate & help you with informed decisions regarding your health.
- Safety Assured Standard of Quality: Our Digestive Enzymes are 3rd-party tested for purity and potency. Each bottle is manufactured w/ love & care in the USA with strict quality control - using imported & domestic ingredients. No Refrigeration Needed
- Nutrient Absorption: Contains a mixture of vegetarian enzymes developed to support nutrient bioavailability and absorption; supports digestion*
- Supports Digestion: Facilitates the normal breakdown of proteins, peptides, polysaccharides and disaccharides; assists with dairy, fiber, and protein digestion*
- Digestive Enzymes: Offers a broad-spectrum combination of vegetarian digestive enzymes designed to provide optimal activity across a wide pH range
- Dairy Enzyme Blend: This vegetarian enzyme blend supports digestion of dairy, sugar, lactose, and certain complex carbs; supports relief from occasional gas or bloating
- Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs
- BREAK IT DOWN: Organic Digest+ offers 29 Certified Organic fruits and vegetables plus a select blend of 13 powerful digestive enzymes including amylase, bromelain, and lactase to help with digestion after meals
- MADE FROM WHOLE FOODS: Dr. Perlmutter formulated Digest+ to be a full spectrum plant-based enzyme formula to aid the digestion of proteins, fats, and carbs; We’ve also included prebiotic fiber from Organic Acacia to support the good bacteria in your gut
- BACKED BY SCIENCE: Our Dr. Formulated Organic Digest+ is the first-ever Certified Organic and Non-GMO digestive enzyme formula that is made from real food and is delivered using Clean Tablet Technology to ensure optimal nutrient absorption
- CONVENIENCE IN MIND: Transport to the tropics after every last bite; Enjoy the benefits of Organic Digest+ in a tropical flavored, shelf stable tablet thats size makes it easy to take on the go; Adults chew 1 tablet after each meal or snack
- EXPERTLY FORMULATED: Our digestive supplement is proudly Dr. Formulated by David Perlmutter, MD and Third-Party Certified Non-GMO, Gluten-Free and Vegan; Made in the USA with no dairy, soy, gluten, peanuts or tree nuts
- For Food Lovers: Savor your favorite dishes worry-free; Our full-strength, bloat-busting digestive enzyme blend helps break down large meals faster, easing bloating and occasional indigestion for care-free indulgence*
- ATPro Blend: Beat the post-meal blues and feel fueled with energy to power through your day; This unique formula features ATPro, a proprietary blend of ATP, Magnesium Citrate, Phytase and CoQ10 that helps fuel your body's cells*
- Effective All the Way Through: Our proprietary Thera-blend enzymes are formulated for optimal activity throughout the digestive system's varying pH levels, providing faster relief and maximum digestive support*
- Dosage: Just 1 capsule daily breaks down up to 34g fat, 16g protein and 86g carbs; Contains no gluten, milk, casein, soy, egg, artificial colors, flavors, or GMOs; Vegan, Kosher and Clean Label Project Certified
- Making a Difference: Enzymedica products harness the power of the finest natural ingredients for maximum effectiveness; We create quality products without compromise while championing initiatives that support the well-being of people and our planet
- Say Goodbye to Meal Time Discomfort: Contains 16 beneficial enzymes that digest proteins, carbs, fruits, veggies, beans, dairy, & fats to cover diverse diets. Includes SBO Probiotics & Prebiotics to aid digestion further - Your New Meal Time Hack! Same great product you love, with a new look. Packaging May Vary!
- Dual Action Relief: Our powerful digestive enzymes aid with breaking down food while the prebiotics & probiotics promote digestive function in the gut. They work synergistically to provide relief from mealtime discomfort.
- Probiotics that Survive the Gut: Formulated with 3 soil-based probiotic strains - specifically selected due to their ability to survive the harsh gut environment. Along with Organic Prebiotics that fuel the growth of healthy bacteria in the gut.
- Science Backed - Our Digestive Enzyme Probiotics are crafted based on scientific research. We have partnered with expert physicians to help review our products & research. We strive to educate & help you with informed decisions regarding your health.
- Safety Assured Standard of Quality: Our Digestive Enzymes are 3rd-party tested for purity and potency. Each bottle is manufactured with love & care in the USA with strict quality control - using imported and domestic ingredients.
- Gluten-free
- Non-GMO
- One 90 count bottle of doctor's best digestive enzymes dietary supplement
- Science-based nutrition
- Vegetarian
- DESIGNED FOR: Those looking for added digestive support potentially related to aging or eating too large of a meal, leading to malabsorption, poor nutrition, and digestive problems such as bloating, gas, and a compromised gut microbiome.**
- FULL SPECTRUM OF ENZYMES: Digest-All contains a full spectrum of carbohydrate, protein, and fat digesting enzymes in a single formula. These enzymes allow you to digest nutrients faster and more effectively helping to alleviate gas and bloating all while improving micronutrient absorption.**
- WITH ADDED: Digest-All Herbal Blend with ginger, peppermint, and triphala
- RECOMMENDATIONS: Take 2 capsules before each meal or as directed by your qualified healthcare provider.
- CERTIFICATIONS: This product is Gluten-Free and 100% vegetarian.
- Complete Full-Spectrum High Potency Digestive Enzyme Supplement
- 120 Capsules Per Bottle
- 1 Serving: Just 1 Capsule
- Non-GMO and 3rd Party Tested
- Made in a GMP Compliant, FDA Registered Facility
- Get Digestive Comfort Now – Ultra Strength 1000 MG Dose of clinical grade digestive enzymes and a 10 billion CFU 10 strain probiotic with prebiotics. Get results & relief fast with more than double the dose of other digestive enzyme supplements. Using organic, systemic, Dr. formulated, & plant based ingredients to ensure the best healthy digestion for adult men & women. Anti bloating, flatulence, fat, pancreatic, & bowel cleansing with Turmeric, Ginger, Papaya, Pectin, Bladderwrack & more.
- Goodbye Hard-to-Digest Foods – This formula features our Advanced Multi Enzyme System to help you digest fried, spicy, raw, processed food, dairy, protein, salts, carb / carbohydrate, vitamin and acidic diet fruits and veggies. Immune-Boosting Probiotic – The gut, biofilm & gallbladder is home to 50% of the body’s immune repair response and this supplement contains a powerful 10 billion CFU dose of 10 different probiotic strains clinically shown to enhance preventions & immune system response.
- Relieve Gas, Belly Bloating / Bloat, Constipation, Leaky, Indigestion, Reflux, Belching & Acid Discomfort! Aid gut health, beauty & bloated stomach comfort. Prebiotic fiber, probiotic encapsulation(Lactobacillus acidophilus, plantarum, casei, salivarius, bulgaricus and Bifidobacterium lactis, bifidum, breve, longum), & enzymes support gut flora bacteria, bile, nutrient absorption, motility, & enzyme levels your body isn't producing as you age.
- Complete digestive enzyme pills complex blend with essential organic blue agave heart, inulin, amylase / amilasa, papain, protease A, invertase, cellulase, hemicellulase, lactase, lipase / lipasa, alpha-galactosidase, fungal pepsin, glucomylase, & bromelina & bromelain supplement. Plus your probiotic supplement and prebiotic supplement (pre & pro) at the same time. All in a convenient purified cap / capsule form which you can open and take as a chewable with dietary nutrients, super food or meal
- Proudly made in the USA in a GMP certified manufacturing facility, 3rd Party Tested, and a 100% satisfaction money back guarantee. If you are not satisfied with our products for any reason, let us know and we’ll make it right. This product is vegan, non-GMO, pure, natural, gluten free, cGMP, wise, dairy free, zen, organic ingredients and is free of soy, peanuts, eggs, gelatin, ox, shellfish, artificial sweeteners, colors, & flavors.
- Nutrient Absorption: Contains a mixture of vegetarian enzymes developed to support nutrient bioavailability and absorption; supports digestion*
- Supports Digestion: Facilitates the normal breakdown of proteins, peptides, polysaccharides, and disaccharides; assists with dairy, fiber, and protein digestion*
- Digestive Enzymes: Offers a broad-spectrum combination of vegetarian digestive enzymes designed to provide optimal activity across a wide pH range
- Enhanced Enzyme Blend: Experience enhanced digestion aid with Betaine HCI; supports optimal gastric pH for normal breakdown of many food types*
- Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs
- COMPLETE GUT WELLNESS: With 15 enzymes plus probiotics and ginger— these veggie capsules are here to promote better nutrient absorption, encourage proper digestion, and help promote stomach regularity*
- HELP EASE STOMACH DIGESTION: Digestive Enzymes from Sports Research is specially formulated to help you digest proteins, fats, fruits, vegetable fiber, dairy products, and carbohydrates, resulting in better nutrient absorption and less digestive discomfort*
- BEAT THE BLOAT: Replenishes enzymes that may decline with age. Our plant-based digestive enzymes with probiotics and ginger work synergistically to help tackle hard-to-digest foods and stomach bloating*
- QUALITY ASSURED: We hold all of our supplements to a higher standard. Rest assured that your digestive enzymes capsules are manufactured in a cGMP-compliant USA facility and third-party tested for quality. Our digestive enzymes capsules are Non-GMO Project Verified, Vegan Friendly, and free of gluten, soy, and unwanted fillers
- THE SPORTS RESEARCH DIFFERENCE: Founded in Southern California in 1980, Sports Research is a family-owned business born from a passion for fitness and wellness. Our goal is to embrace the sport of life through research-backed products created for every body—inside and out (Please remove product label before recycling bottle)
- Support Food Breakdown + Nutrient Absorption - This digestive enzyme supplement is a multi enzyme blend of a proprietary blend of digestive enzymes alongside hcl betaine with pepsin to support gut health and optimal digestion of proteins, fats, and carbohydrates.*
- Occasional Gas or Bloating After Meals? Enzymes for digestion may be helpful for those experiencing occasional gas after eating, constipation, or a feeling of fullness after eating only a small quantity of food.* The use of Digestzyme before meals may offer occasional mild bloating relief. Take one digestion supplement capsule before meals to support digestive gut health.*
- Pancreatic Enzymes + Betaine HCl - Protease DPP IV aids in the breakdown of casomorphin (from casein protein) and gluteomorphin (from gluten). Lactase enzyme helps break down the dairy sugar lactose, while lipase support fats and fat-soluble vitamins. The betaine hydrochloride supplement supports protein digestion and nutrient absorption.*
- Why Add Bile Salts to Your Digestive Enzyme Blend? Ox bile provides bile acids, which are key to the digestion of fat and fat-soluble vitamins. Ox bile digestive enzymes formulas can offer further support for malabsorption and maldigestion, including fats.*
- Clinically-Trusted Care - DFH is the #1 practitioner supplement brand recommended by functional medicine professionals and the #1 practitioner supplement brand personally trusted by functional medicine professionals.**
- Breaks down fat, fiber, protein & carbs
- Speeds up digestion
- Reduces occasional gas, bloating & indigestion
- ALL NATURAL: You deserve to know what you're putting in your body; We use only the highest quality ingredients from the purest sources available
- Ultra Digestive Food Enzymes: Enhance Digestion With This Ultra Digestive Food Enzyme Blend. This supplement is formulated to enable digestion, especially in those with digestive issues, amplifying nutrient absorption.
- Multiple Benefits: This extra strength blend of enzymes are formulated to help digest proteins, carbohydrates, fiber, fat, and lactose. This supplement was specifically formulated to support digestion, as well as reduce occasional bloating and gas.
- Vegan Formula: We include more of every enzyme that can help you feel your best: Protease, Amylase, Glucoamylase, Diastase, Invertase, Pectinase, Cellulase, Hemicellulase, Xylanase, Lipase, Lactase, Alpha-Galactosidase, and Beta-Glucanase. Our enzymes also include Vitamin B1, B6, B12, Calcium, Magnesium, Manganese, Amla, and Phytase. Other Ingredients: Hypromellose, Maltodextrin, Calcium Phosphate.
- Easy Efficient Absorption: Formulated for men and women. Each bottle contains 60 capsules, with a serving size of 1 capsule, and will last 1-2 months. Adults take 1 capsule prior to each meal or as recommended by physician or healthcare professional. Keep out of reach of children in case of accidental overdose or choking. Store in a cool, dry place.
- MaryRuth's Ultra Digestive Food Enzymes are Vegan, Non-GMO Project Verified, and Made in a GMP (Good Manufacturing Practice) Facility. Dairy Free, Nut Free, Gluten Free, Soy Free, Sugar Free. Clean Label Project Certified. B Corp Certified.
- FULL SPECTRUM ENZYMES: Take 2 NOW Optimal Digestive System capsules with or before each meal for maximum food utilization.
- CERTIFICATIONS/CLASSIFICATIONS: Quality GMP Assured, Vegan/Vegetarian, Soy Free, Keto Friendly
- HELPS WITH BEAN AND CABBAGE DIGESTION: Offers a blend of enzymes that will aid in the digestion of most foods, including beans and cruciferous vegetables.
- BioCore Optimum
- A Dietary Supplement
How to choose a good digestive enzymes
Does the idea of finding a fantastic digestive enzymes make you anxious? When it comes to purchasing this product, specifically when deciding which model to select, has your head been spinning between options? You are not alone if that is the case. We are aware of the pressure involved in the purchasing process!
Your presence here indicates that you are interested in digestive enzymes. Before choosing which product would be the best for your needs after being inundated with information, locate a reliable source with genuine selections. You can get that information from a variety of sources, including buying guides and rating websites, word-of-mouth recommendations from friends and family, online discussion forums where users can share their own experiences, product reviews that can be found all over the internet, and YouTube channels. You can only get the right product through exhaustive analysis. But you realize that’s not always simple. In order to ease your concerns, we have taken the time to develop a list of the top digestive enzymes products available right now. You might be wondering how we came up with the list. How was this buying guide developed?
First, we used our algorithms to gather as much reliable data as we could about these products. To verify all the data gathered, we used both artificial intelligence and a lot of algorithms.
Then, our experts used criteria that are recognized in the business to evaluate them according to their quality to price ratio, allowing us to choose the top digestive enzymes on the market right now!
The selection of the goods is not arbitrary. Before creating a list, we take into account a number of factors. Below are some of the criteria discussed:
Brand Value: What happens if you choose a dubious brand just because it appears to be a good deal? So the likelihood of receiving a product with a short shelf life increases. That is due to the fact that well-known brands have a reputation to uphold, while others do not. Top digestive enzymes brands strive to provide some distinctive traits that set them apart from the competition. So, hopefully one or more of the items on our list will be perfect for you.
Features: Useful features are all you need, not tons of them. We consider the important aspects and select the top digestive enzymes based on those.
Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products with higher specifications, but with the right balance.
Quality: A product’s quality may always be quantified with the aid of numbers. We look for goods with better standards that strike the proper balance. The best quality product that gets highly appreciated and recommended by experienced users.
Customer ratings: Would it be accurate to suggest that the digestive enzymes were used by hundreds of customers before you? Superior ratings indicate that many customers had better service.
Customer Reviews: Like ratings, provide you with accurate and reliable information about the product from genuine customers. Customer ratings are very important to all of us because they contain accurate and reliable information about the customer service we received from several hundred customers.
Seller Rank: This is very intriguing! Not only do you need a good digestive enzymes, you also need a product with rising sales that is trendy. It accomplishes two goals. First, the expanding user base proves the quality of the product. Second, given that number, producers must be able to offer greater quality and after-sales support.
Value: You get what you pay for, they say, so consider the value. Cheap isn’t always good and expensive isn’t always bad. However, that does not imply that spending a lot of money on a product that is flashy but underwhelming is a good idea. Before adding them to the list, we make an effort to evaluate how much value you can get for your money from your digestive enzymes.
Durability: Durability and reliability are closely related concepts. You will benefit from a strong and long-lasting digestive enzymes for months and years to come.
Product availability: Products come and go, and new ones replace the old ones. Most likely, a few new features and required changes were made. What use is it to use a supposedly good product if the maker no longer supports it? We make an effort to highlight products that are current and offered by one or more trustworthy sellers, if not more.
Negative Reviews: Yes, we do take that into account as well! The goods with the majority of bad reviews are filtered out and disregarded when we choose the best-rated one on the market.
These are the standards by which we selected our digestive enzymes. Do we end our process there? Hell no. The most crucial fact about us that you should be aware of is that we regularly update our website with current and pertinent information. We have one more layer of filtration since we place the greatest importance on reader satisfaction. Please let us know if any product included here is incorrect, irrelevant, subpar, or simply out of date. We always value your opinions, and we’ll work hard to make any necessary corrections to our list in response to them.
Why should you believe us?
There are now thousands of possibilities for these products on Amazon, but choosing the best one can be difficult and time-consuming. And what digestive enzymes should you purchase in 2022?
This guide is the result of more than 10 years of experience in researching, testing and writing about many topics. Each member of our team is an authority in their area. We read every article we could find online and every consumer review on every retail website for seven hours. Additionally, we discovered a ton of websites that offered helpful resources, including buying tips and thorough information on digestive enzymes.
Related posts:
- The 8 Best digestive enzyme for human of 2025
- The 8 Best digestive enzyme for dogs of 2025
- The 8 Best digestive enzyme for keto of 2025
- The 8 Best digestive enzyme for beans of 2025
- The 8 Best digestive enzyme supplements of 2025
- The 8 Best digest for dogs of 2025
- The 8 Best peppermint for bloating of 2025
- The 8 Best gut knives of 2025
- The 8 Best formulated for natural busts of 2025
- The 8 Best dog digestive health of 2025