Are you trying to find enzyme cleaners among various brands on the market but aren’t sure where to begin? To assist you in finding the right one, we’ve put together a list of the 7 best to help you pick the perfect one!
We investigated and evaluated a number of the top-selling enzyme cleaners on the market in order to create our list of the best. Making a decision among the many options available is never simple. There are an infinite number of models available, each with a distinct price. And as you’ll find out, the best options aren’t usually the ones you imagine! This comparison is rich and relevant because of the numerous factors that were employed. You will find products featured in this ranking not only based on their pricing but also on their features and other customers reviews. To write this review, we completed 12 hours of research and did 28 enzyme cleaners tests. You won’t need to pick products at random any more. If you’re unsure of what to look for, browse our list and consult the buying guide!
An overview of our top picks
Table of contents
The best enzyme cleaners you can buy today
- 1 gallon bottle of multi-purpose enzyme cleaning solution for a wide variety of surfaces and environments
- Breaks up complex organic proteins, pet smells and stains, hair, grease, oils, and more for effective results
- Ideal for commercial properties, retail, and hospitality
- Use as needed on stains and problem areas for spot cleaning carpet, surfaces, drains, toilets, grease traps, and more
- Pro Grade Clean - Zeiff Pro-Grade Formulas are innovative, unique proprietary solutions, trusted by professionals and consumers for being the most effective cleaning products to get the job done. Whether you’re a pro or just expect pro-grade results, Zeiff delivers Pro Grade Clean
- Powerful Cleaning Performance - Our super strength proprietary formulation breaks up and digests complex organic proteins, pet stains, hair, grease, fats, and oils, easily cutting through dirt, grease and grime without leaving any visible residue. Don't just expect clean, expect Zeiff Clean! You'll know it when you see it, clean you didn't even know exists
- Multi-Purpose Enzyme Cleaner - The drain odor eliminator is a special blend of powerful bacterial enzymes, detergent and deodorant, that prevents clogging in drains, garbage disposals, grease traps, sinks, toilets, urinals, septic tanks, drain lines and downpipes. The floor and carpet stain remover cleans stains, odors, carpets, upholstery, fabric, laundry, floors, hardwood, laminate, kitchen & bathroom surfaces, and much more. Ideal for Professional and Home use
- Deodorizer & Odor Eliminator - The dog enzyme cleaner and pet odor eliminator for home is a highly concentrated bacterial digestant for grease, stains, oils, & organic waste. The pet urine enzyme cleaner effectively eliminates foul odors caused by urine, feces, blood, vomit, food, garbage and grease, leaves long-lasting freshness, with a subtle lavender breeze that instantly refreshes any space with a pleasant aroma, great pet enzyme urine cleaner and cat odor eliminator
- Safe & Effective - Zeiff Pro Grade Formulas are safe & effective, non-corrosive, non-flammable, non-acidic, free of caustics and dyes, pH neutral, paraben-free, pet safe, cruelty-free. Proudly made in the USA
- ✅ COMBAT ORGANIC MESSES : Enzyme cleaner emits enzymes to break down molecules found in organic material like grass, blood, urine, vomit feces, and food. Once it breaks the molecules down into smaller pieces, the raising agent swoops in to consume those molecules.
- ✅ MULTI-PURPOSE: Proprietary blend of enzymes breaks up complex organic proteins, pet stains, hair, grease, fats, and oils, easily cutting through dirt, grease, and grime without leaving any visible residue. Don't just expect clean, expect Enzyme Clean!
- ✅ MULTI-SURFACE: Nanoskin Enzyme has a special blend of beneficial enzymes, detergent, and deodorant, prevents clogging in drains, grease traps, septic tanks, drain lines, and downpipes and cleans stains, odors, carpets, floors, kitchen & bathroom surfaces, and much more. Ideal for professional detailer and home use.
- ✅ ELIMINATE FOUL ODORS: Effectively eliminates foul odors caused by urine, feces, blood, vomit, food, garbage, and grease and leaves long-lasting freshness. Nanoskin Enzyme is fragrance free with no artificial fragrance to cover the odor. Safe to use around pets and children.
- ✅ EASY & SAFE TO USE: Ready-to-Use formula. Nanoskin Enzyme is formulated to be safe & effective, non-corrosive, non-flammable, non-acidic, free of caustics and staining dyes, pH neutral, paraben-free. Unique proprietary solutions, trusted by professionals and consumers.
- MAXIMUM CLEANING EFFECTIVENESS: Bac-Out safely cleans and deodorizes soap scum, build-up, and unpleasant odors and urine stains to keep your bathroom looking great and smelling fresh.
- MULTIPLE USES AND SURFACES: Clean and eliminate grime using the aromatic joy of Lavender Lime on floors, showers, tubs, tile, toilets, sinks and countertops.
- BIO-ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It's a more natural way to remove buildup and stinky odors.
- PLANT-BASED CLEANER: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates, chlorine, ammonia, or brighteners.
- MADE IN THE USA: We use biodegradable ingredients, never test on animals, and are manufactured in the USA with US and imported parts
- PROBIOTICS CHANGE EVERYTHING: Traditional enzyme cleaners work, sorta, but they're old news. High-density probiotic cleaners keep on producing highly targeted, protein-specific enzymes until odor-causing matter is eliminated deep at the source, for far superior all-purpose efficacy.
- PROFESSIONAL CLEANING POWER: Experience professional level, deep cleaning action, whether you are using our product as a urine enzyme cleaner or odor eliminator, to eliminate pet stains, to remove hair, grease, and oils deep in drain and septic systems, or even carpet cleaning in a steam cleaner.
- MAKES ODORS HEAVIER THAN AIR: Featuring a novel, zinc-based odor counteractant, boasting a massive surface area, our solution covers biological matter and smothers it, preventing odor-causing gases from rising to the surface, neutralizing residual smells, and providing relief while other active ingredients get to work.
- THERE'S STILL MORE: Calyptus all-purpose probiotic and enzyme cleaner solution even features orange oil and plant-based cleaning surfactants to expediently break down and degrease oily residue assisting our probiotics and odor counteractants deep down for a more effective cleaning experience.
- JOIN THE CALYPTUS FAMILY – INTENT MATTERS: When you choose Calyptus, you're joining a growing community of millions who trust us to deliver intentional, innovative solutions, that respect and harness the power of nature, for superior and safer cleaning performance, in and around your home.
- ✅Proudly made in the USA, we ensure that we deliver top-tier quality with every bottle. This versatile cleaner is designed to provide outstanding cleaning results on various surfaces, giving you the ultimate cleaning experience.
- ✅One of the standout features is that our ORANGE ENZYME Cleaner is a Super Concentrate! A 128 oz bottle makes an astonishing 64 gallons, And 64 oz bottle makes an astonishing 32 gallons, needing just 2 oz per gallon. This not only saves you time but also reduces the need for multiple cleaning products around the house, leading to incredible savings!
- ✅The cleaner effectively tackles dirt and grime without harming surfaces or causing any discoloration. You can trust it won’t strip away protective finishes or leave behind streaks or residue.
- ✅Additionally, our cleaner leaves a long-lasting refreshing orange scent that lingers, making your home smell inviting and clean hours after you've finished your chores.
- ✅Whether you need to clean floors, treat tough spots, or need a refreshing spray, ORANGE ENZYME has you covered! It’s suitable for a wide range of surfaces, from floors and counters to walls and appliances.
- ✅Don't hesitate to elevate your cleaning routine! Try ORANGE ENZYME today and experience the unparalleled cleaning power!
- STAIN AND ODOR REMOVER: Bac-Out safely works wonders on pet accidents, wine spills on carpets and couches, cloth diapers and pails, laundry, disposals, garbage cans and much more.
- PREFERRED BY PROFFESSIONALS: Bac-Out is the preferred choice of commercial carpet cleaners nationwide.
- BIO ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It's a more natural way to remove buildup and stinky odors.
- PLANT BASED CLEANER: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates, chlorine, ammonia, or brighteners.
- MADE IN THE USA: We use biodegradable ingredients, never test on animals, and are manufactured in the USA with US and imported parts
- Permanently eliminates tough stains and unpleasant odors from urine, feces, vomit, scent markings, dirt, blood and more
- Use on carpets, rugs, pet bedding, upholstery, clothing, curtains, Auto upholstery, litter boxes, crates and carriers, tile, finished wood, laminates, concrete and more
- Uses powerful, natural enzymes to eliminate odors at the source rather than cover them up
- Safe for use around pets
- Eliminates new, old and set-in stains
- ELIMINATES THE STUFF OF STAINS AND STINKS: The bio-enzymatic spray activates on contact with ammonia crystals and organic matter and doesnt stop working until it has eliminated every trace of urine, feces, vomit and any other gross stuff it digs up.
- GIVE IT PERMISSION TO GO ANYWHERE IN YOUR HOUSE: You can trust it on carpets, floors, furniture, clothing, litter boxes, kennels, carrier, anywhere pets can go and stains could happen.
- WELL-BEHAVED AROUND PETS AND KIDS: With no chlorine, no chemical propellants, and nothing that stains or fades colors, its your houses best friend. Its even been Certified Safe for all carpets, fetching the Seal of Approval by the trusted Carpet and Rug Institute (CRI).
- 100% SATISFACTION GUARANTEED: If your worst stains and odors arent gone, neither is your money. Well give you a full refund, no questions asked.
- Permanently eliminates tough stains and unpleasant odors from urine, feces, vomit, scent markings, dirt, blood and more
- Use on carpets, rugs, pet bedding, upholstery, clothing, curtains, Auto upholstery, litter boxes, crates and carriers, tile, finished wood, laminates, concrete and more
- Uses powerful, natural enzymes to eliminate odors at the source rather than cover them up
- Safe for use around pets
- Eliminates new, old and set-in stains
- EFFECTIVE CLEANING: Safely cleans any hard surface. Multi-Surface is great for walls, floors, granite, cabinets, drawers, countertops, furniture, and many other hard surfaces.
- HOW IT WORKS: The Pure & Fresh Enzymes break down dirt and grime into their basic elements. The enzyme formula destroys the soils, it doesn't just push the grime around like plain soaps.
- ECO-FRIENDLY: Naturally It’s Clean products are safer for your children, pets, and the environment. No harsh fumes, vapors, phosphates, chlorine, SLS or petroleum. Also, try our concentrate refill to reduce your costs and environmental waste.
- EASY TO USE: Naturally It’s Clean Multi-Surface Cleaner, in two (2) 24oz Ready-To-Use Spray Bottles (total 48oz), is easy to use. Spray on any surface, then wipe away dirt, grease, food and odors.
- MADE IN USA: Manufactured in our plant in Indiana.
- ENZYME ENHANCED FORMULA: Green Gobbler Enzymatic Drain & Grease Trap Cleaner uses an enzyme enhanced formula to clear buildup and remove odors in grease traps, septic tanks and similar plumbing systems. It helps digests oils, fats, grease, sludge and other food waste within hours of application. This bottle uses anti-glug technology to help reduce splashing and provides up to eight treatments.
- SAFE FOR PIPES: Green Gobbler helps maintain drain lines, septic tanks, grease traps and grease interceptors. Our enzyme enhanced formula is an excellent alternative to sodium hydroxide and other caustic chemicals.
- IMPROVE GREASE TRAP EFFICIENCY: Green Gobbler increases the efficacy of grease traps by allowing enzymes & bacteria to work more efficiently to promote the separation of water and grease, helping your trap run more smoothly.
- KEEP SEPTIC TANKS HEALTHY: Green Gobbler helps prompt the biological breakdown of foul odors and organic material inside demanding environments such as drains, pipes and septic tanks.
- GREEN GOBBLER GUARANTEE: Green Gobbler cares about its customers. We take pride in developing innovative & effective products for your home or business. If for any reason you are unsatisfied, please contact us. We offer a money-back guarantee within 30 days of purchase.
- Powerful & Natural Odor Eraser: This chemical-free formula is a pet poop & pee smell destroyer. Spray it on any outdoor surface, and odors will quickly disappear. The only thing left behind will be a fresh eucalyptus scent.
- Multi-Surface Safe: This natural professional strength formulation does not contain any harsh chemicals and is safe for use around plants and on grass. Nasty smells on dirt, driveways, dog runs, gravel, patio furniture, and more are no match for Eco Strong.
- Pet Paw & Barefoot Safe: The bio-enzymatic solution erases organic waste odors at the source without leaving behind any residue.
- No Hose Required: Ditch the hose and hassle with the 2oz shots and halo sprayer.Quickly and easily treat apartment balconies, potty areas, your pet’s favorite tree or fence post, and even inside your trash cans.
- Proudly Made In The USA: Eco Strong does not mask foul animal organic scents – it destroys them at the source.
- POWERFUL 2 IN 1 ENZYME STAIN + ODOR FIGHTING - Angry Orange enzyme-active cleaner breaks down and eliminates stains from pet urine, feces and vomit.
- MULTIPURPOSE - Can be used to eliminate stains from carpet, tile, hardwoord, couch upholstery, car interiors, turf, and more.
- DIRECTIONS FOR USE - For best results, remove pets from area, clean excess mess, shake well & spray, let enzymes eat away at the stains.
- CITRUS SCENT - Angry Orange Enzyme Cleaner will break down, not mask, your stains and leave a fresh citrus smell.
- CUSTOMER SERVICE - If you're not satified reach out to our responsive customer service team.
- PET STAIN AND ODOR REMOVER: Things can get a little messy when your pet is involved - that’s where we come in; This extra-strength cleaning solution is specially formulated to tackle the toughest smells & dirtiest spots left behind by your beloved pets.
- EXTREME ENZYMATIC CLEANER: This professional strength spray consists of a powerful enzyme formula three times stronger than our regular formula, specialized for breaking down, eliminating, and permanently neutralizing both new and old stains and odors.
- FOR DOGS AND CATS: Say goodbye to bad messes - This dog and cat-specific cleaning spray is the best thing for cleaning up after urine, feces, vomit, and all the stains and smells that accompany them; It is a pet-safe and family-friendly cleaning option
- MULTIFUNCTION SPRAY: This cleaner can be used for carpets, upholstery, bedding, fabric toys, clothing, & other water-safe surfaces in your home; It uses a patented 3-in-1 nozzle with mist, foam, and stream features so you can pick the best way to clean up
- SIMPLE SOLUTION: it’s just that…a simple solution to all of your pets’ messes – wherever they may be; We offer easy-to-use, no-hassle products that will effectively help you keep your home clean and sparkling; In short - pet parenting made easy.
- Certified Gentle And Safe: Chlorine free and color safe; Safe to use around pets and children; No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (cri)
- Eliminates Stains, Odors and Residue: If it’s gross, it’s gone; Not just the stain, but the stink; From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all
- Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen
- Enzyme Activated: The key is getting to the problem deep-down; This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated
- Buy With Confidence: You want the best for your best friend; We do, too; If you are not satisfied with the performance of this product, contact us; We are determined to make it right
- YOUR MOP'S NEW BFF: The perfect cleaning companion to your O-Cedar mop bucket is finally here! Concentrated O-Cedar PACS are packed with the deep cleaning power of enzymes to make floor cleaning a breeze.
- PERFECTLY PORTIONED & CONVENIENT: With O-Cedar PACS, you won't have to worry about guessing or making a mess. Simply drop one of our PACS into 1.6 gallons of water and watch it fizz! Once the bubbles stop, it's time to mop.
- POWERFUL ENZYMES FOR A DEEP CLEAN: O-Cedar PACS use concentrated enzymes that bind to stubborn dirt and grime particles, dissolving them away for a thorough, streak-free clean you can trust.
- NO HARSH CHEMICALS: The formula is made with 97% naturally derived ingredients and plant-based surfactants that break down dirt and grime, and is gentle on all hard floors. No ammonia, no bleach or parabens.
- TWO REFRESHING SCENTS: O-Cedar Floor Cleaning Pods are available in Crisp Citrus and Lavender scents, leaving your floors smelling fresh and clean.
- SPOT STAIN & ODOR REMOVER: Begins to break down and remove cat stains immediately on contact.
- LIGHT CITRUS SCENT: Cat odor control formula gets your home smelling clean again.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
- TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works.
- SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets.
- CAT STAIN AND ODOR REMOVER: Things can get a little messy when your furry feline is involved - that’s where we come in; This extra-strength solution is specially formulated to tackle the toughest smells & dirtiest spots left behind by your beloved pet
- EXTREME ENZYMATIC CLEANER: This professional strength spray consists of a powerful enzyme formula 2 times stronger than our regular formula, specialized for breaking down, eliminating, and permanently neutralizing both new and old stains and odors
- STAIN AND URINE DESTROYER FOR CATS: Say goodbye to bad messes - This cat-specific cleaning spray is the best thing for cleaning up after urine, feces, vomit, and all the stains and smells that accompany them; Pet-safe and family-friendly cleaning option
- MULTIFUNCTION CARPET SPRAY: This cleaner can be used on carpets, upholstery, bedding, fabric toys, clothing, & water-safe surfaces in your home; It uses a patented 3-in-1 nozzle with mist, foam, and stream features so you can pick the best way to clean up
- SIMPLE SOLUTION: it’s just that…a simple solution to all of your pets’ messes – wherever they may be; We offer easy-to-use, no-hassle products that will effectively help you keep your home clean and sparkling; In short - pet parenting made easy
- REMOVES PET STAINS- Simple Solution Stain & Odor Remover is formulated to eliminate and neutralize tough dog and cat stains and odors like urine, feces, and vomit
- UNIQUE PRO-BACTERIA FORMULA - This stain and odor remover has a unique Pro-Bacteria and enzyme formula that eliminates stains and odors, and helps prevent repeat marking
- MULTIPLE USES - Safely removes dog and cat stains and odors from carpet, upholstery, bedding, fabric toys, clothing, and other water-safe surfaces in your home
- VERSATILE CLEANING - Our patented 3-in-1 nozzle sprayer gives you more options to tackle stains and odor: stream, foam, or mist
How to choose a good enzyme cleaners
Does the idea of finding a fantastic enzyme cleaners make you anxious? When it comes to purchasing this product, specifically when deciding which model to select, has your head been spinning between options? You are not alone if that is the case. We are aware of the pressure involved in the purchasing process!
Your presence here indicates that you are interested in enzyme cleaners. Before choosing which product would be the best for your needs after being inundated with information, locate a reliable source with genuine selections. You can get that information from a variety of sources, including buying guides and rating websites, word-of-mouth recommendations from friends and family, online discussion forums where users can share their own experiences, product reviews that can be found all over the internet, and YouTube channels. You can only get the right product through exhaustive analysis. But you realize that’s not always simple. In order to ease your concerns, we have taken the time to develop a list of the top enzyme cleaners products available right now. You might be wondering how we came up with the list. How was this buying guide developed?
First, we used our algorithms to gather as much reliable data as we could about these products. To verify all the data gathered, we used both artificial intelligence and a lot of algorithms.
Then, our experts used criteria that are recognized in the business to evaluate them according to their quality to price ratio, allowing us to choose the top enzyme cleaners on the market right now!
The selection of the goods is not arbitrary. Before creating a list, we take into account a number of factors. Below are some of the criteria discussed:
Brand Value: What happens if you choose a dubious brand just because it appears to be a good deal? So the likelihood of receiving a product with a short shelf life increases. That is due to the fact that well-known brands have a reputation to uphold, while others do not. Top enzyme cleaners brands strive to provide some distinctive traits that set them apart from the competition. So, hopefully one or more of the items on our list will be perfect for you.
Features: Useful features are all you need, not tons of them. We consider the important aspects and select the top enzyme cleaners based on those.
Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products with higher specifications, but with the right balance.
Quality: A product’s quality may always be quantified with the aid of numbers. We look for goods with better standards that strike the proper balance. The best quality product that gets highly appreciated and recommended by experienced users.
Customer ratings: Would it be accurate to suggest that the enzyme cleaners were used by hundreds of customers before you? Superior ratings indicate that many customers had better service.
Customer Reviews: Like ratings, provide you with accurate and reliable information about the product from genuine customers. Customer ratings are very important to all of us because they contain accurate and reliable information about the customer service we received from several hundred customers.
Seller Rank: This is very intriguing! Not only do you need a good enzyme cleaners, you also need a product with rising sales that is trendy. It accomplishes two goals. First, the expanding user base proves the quality of the product. Second, given that number, producers must be able to offer greater quality and after-sales support.
Value: You get what you pay for, they say, so consider the value. Cheap isn’t always good and expensive isn’t always bad. However, that does not imply that spending a lot of money on a product that is flashy but underwhelming is a good idea. Before adding them to the list, we make an effort to evaluate how much value you can get for your money from your enzyme cleaners.
Durability: Durability and reliability are closely related concepts. You will benefit from a strong and long-lasting enzyme cleaners for months and years to come.
Product availability: Products come and go, and new ones replace the old ones. Most likely, a few new features and required changes were made. What use is it to use a supposedly good product if the maker no longer supports it? We make an effort to highlight products that are current and offered by one or more trustworthy sellers, if not more.
Negative Reviews: Yes, we do take that into account as well! The goods with the majority of bad reviews are filtered out and disregarded when we choose the best-rated one on the market.
These are the standards by which we selected our enzyme cleaners. Do we end our process there? Hell no. The most crucial fact about us that you should be aware of is that we regularly update our website with current and pertinent information. We have one more layer of filtration since we place the greatest importance on reader satisfaction. Please let us know if any product included here is incorrect, irrelevant, subpar, or simply out of date. We always value your opinions, and we’ll work hard to make any necessary corrections to our list in response to them.
Why should you believe us?
There are now thousands of possibilities for these products on Amazon, but choosing the best one can be difficult and time-consuming. And what enzyme cleaners should you purchase in 2022?
This guide is the result of more than 10 years of experience in researching, testing and writing about many topics. Each member of our team is an authority in their area. We read every article we could find online and every consumer review on every retail website for seven hours. Additionally, we discovered a ton of websites that offered helpful resources, including buying tips and thorough information on enzyme cleaners.
