Are you trying to find enzyme cleaners among various brands on the market but aren’t sure where to begin? To assist you in finding the right one, we’ve put together a list of the 7 best to help you pick the perfect one!
We investigated and evaluated a number of the top-selling enzyme cleaners on the market in order to create our list of the best. Making a decision among the many options available is never simple. There are an infinite number of models available, each with a distinct price. And as you’ll find out, the best options aren’t usually the ones you imagine! This comparison is rich and relevant because of the numerous factors that were employed. You will find products featured in this ranking not only based on their pricing but also on their features and other customers reviews. To write this review, we completed 12 hours of research and did 28 enzyme cleaners tests. You won’t need to pick products at random any more. If you’re unsure of what to look for, browse our list and consult the buying guide!
An overview of our top picks
Table of contents
The best enzyme cleaners you can buy today
- 1 gallon bottle of multi-purpose enzyme cleaning solution for a wide variety of surfaces and environments – use on carpets, furniture, hardwood, tile, drains, liter boxes, garbage cans, RVs and more
- Breaks up complex organic proteins, pet smells and stains, grease, oils, and more for effective results
- Powerful enzymatic formula removes stains and odors deep in the carpet
- Attack grease, fats and other organic matter that cause slow drains and unpleasant odors - not a hazardous, caustic drain opener effective on bathroom clogs from hair
- Non-corrosive, non-flammable, non-acidic, and non-caustic with a fresh mint scent
- Pro Grade Clean - Zeiff Pro-Grade Formulas are innovative, unique proprietary solutions, trusted by professionals and consumers for being the most effective cleaning products to get the job done. Whether you’re a pro or just expect pro-grade results, Zeiff delivers Pro Grade Clean
- Powerful Cleaning Performance - Our super strength proprietary formulation breaks up and digests complex organic proteins, pet stains, hair, grease, fats, and oils, easily cutting through dirt, grease and grime without leaving any visible residue. Don't just expect clean, expect Zeiff Clean! You'll know it when you see it, clean you didn't even know exists
- Multi-Purpose Enzyme Cleaner - The drain odor eliminator is a special blend of powerful bacterial enzymes, detergent and deodorant, that prevents clogging in drains, garbage disposals, grease traps, sinks, toilets, urinals, septic tanks, drain lines and downpipes. The floor and carpet stain remover cleans stains, odors, carpets, upholstery, fabric, laundry, floors, hardwood, laminate, kitchen & bathroom surfaces, and much more. Ideal for Professional and Home use
- Deodorizer & Odor Eliminator - The dog enzyme cleaner and pet odor eliminator for home is a highly concentrated bacterial digestant for grease, stains, oils, & organic waste. The pet urine enzyme cleaner effectively eliminates foul odors caused by urine, feces, blood, vomit, food, garbage and grease, leaves long-lasting freshness, with a subtle lavender breeze that instantly refreshes any space with a pleasant aroma, great pet enzyme urine cleaner and cat odor eliminator
- Safe & Effective - Zeiff Pro Grade Formulas are safe & effective, non-corrosive, non-flammable, non-acidic, free of caustics and dyes, pH neutral, paraben-free, pet safe, cruelty-free. Proudly made in the USA
- ✅ COMBAT ORGANIC MESSES : Enzyme cleaner emits enzymes to break down molecules found in organic material like grass, blood, urine, vomit feces, and food. Once it breaks the molecules down into smaller pieces, the raising agent swoops in to consume those molecules.
- ✅ MULTI-PURPOSE: Proprietary blend of enzymes breaks up complex organic proteins, pet stains, hair, grease, fats, and oils, easily cutting through dirt, grease, and grime without leaving any visible residue. Don't just expect clean, expect Enzyme Clean!
- ✅ MULTI-SURFACE: Nanoskin Enzyme has a special blend of beneficial enzymes, detergent, and deodorant, prevents clogging in drains, grease traps, septic tanks, drain lines, and downpipes and cleans stains, odors, carpets, floors, kitchen & bathroom surfaces, and much more. Ideal for professional detailer and home use.
- ✅ ELIMINATE FOUL ODORS: Effectively eliminates foul odors caused by urine, feces, blood, vomit, food, garbage, and grease and leaves long-lasting freshness. Nanoskin Enzyme is fragrance free with no artificial fragrance to cover the odor. Safe to use around pets and children.
- ✅ EASY & SAFE TO USE: Ready-to-Use formula. Nanoskin Enzyme is formulated to be safe & effective, non-corrosive, non-flammable, non-acidic, free of caustics and staining dyes, pH neutral, paraben-free. Unique proprietary solutions, trusted by professionals and consumers.
- MAXIMUM CLEANING EFFECTIVENESS: Bac-Out safely cleans and deodorizes soap scum, build-up, and unpleasant odors and urine stains to keep your bathroom looking great and smelling fresh.
- MULTIPLE USES AND SURFACES: Clean and eliminate grime using the aromatic joy of Lavender Lime on floors, showers, tubs, tile, toilets, sinks and countertops.
- BIO-ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It's a more natural way to remove buildup and stinky odors.
- PLANT-BASED CLEANER: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates, chlorine, ammonia, or brighteners.
- MADE IN THE USA: We use biodegradable ingredients, never test on animals, and are manufactured in the USA with US and imported parts
- PROBIOTICS CHANGE EVERYTHING: Traditional enzyme cleaners work, sorta, but they're old news. High-density probiotic cleaners keep on producing highly targeted, protein-specific enzymes until odor-causing matter is eliminated deep at the source, for far superior all-purpose efficacy.
- PROFESSIONAL CLEANING POWER: Experience professional level, deep cleaning action, whether you are using our product as a urine enzyme cleaner or odor eliminator, to eliminate pet stains, to remove hair, grease, and oils deep in drain and septic systems, or even carpet cleaning in a steam cleaner.
- MAKES ODORS HEAVIER THAN AIR: Featuring a novel, zinc-based odor counteractant, boasting a massive surface area, our solution covers biological matter and smothers it, preventing odor-causing gases from rising to the surface, neutralizing residual smells, and providing relief while other active ingredients get to work.
- THERE'S STILL MORE: Calyptus all-purpose probiotic and enzyme cleaner solution even features orange oil and plant-based cleaning surfactants to expediently break down and degrease oily residue assisting our probiotics and odor counteractants deep down for a more effective cleaning experience.
- JOIN THE CALYPTUS FAMILY – INTENT MATTERS: When you choose Calyptus, you're joining a growing community of millions who trust us to deliver intentional, innovative solutions, that respect and harness the power of nature, for superior and safer cleaning performance, in and around your home.
- Super Concentrate makes up to 64 GALLON
- Powerful Stain and Odor Eliminator Multi-Purpose Enzyme Cleaner
- Orange Pet Odor Eliminator for Home
- Strong Odor Floor Cleaner USA Made Plant Based All Purpose Cleaner and Deodorizer 128 Ounces
- STAIN AND ODOR REMOVER: Bac-Out safely works wonders on pet accidents, wine spills on carpets and couches, cloth diapers and pails, laundry, disposals, garbage cans and much more.
- PREFERRED BY PROFFESSIONALS: Bac-Out is the preferred choice of commercial carpet cleaners nationwide.
- BIO ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It's a more natural way to remove buildup and stinky odors.
- PLANT BASED CLEANER: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates, chlorine, ammonia, or brighteners.
- MADE IN THE USA: We use biodegradable ingredients, never test on animals, and are manufactured in the USA with US and imported parts
- Permanently eliminates tough stains and unpleasant odors from urine, feces, vomit, scent markings, dirt, blood and more
- Use on carpets, rugs, pet bedding, upholstery, clothing, curtains, Auto upholstery, litter boxes, crates and carriers, tile, finished wood, laminates, concrete and more
- Uses powerful, natural enzymes to eliminate odors at the source rather than cover them up
- Safe for use around pets
- Eliminates new, old and set-in stains
- ELIMINATES THE STUFF OF STAINS AND STINKS: The bio-enzymatic spray activates on contact with ammonia crystals and organic matter and doesnt stop working until it has eliminated every trace of urine, feces, vomit and any other gross stuff it digs up.
- GIVE IT PERMISSION TO GO ANYWHERE IN YOUR HOUSE: You can trust it on carpets, floors, furniture, clothing, litter boxes, kennels, carrier, anywhere pets can go and stains could happen.
- WELL-BEHAVED AROUND PETS AND KIDS: With no chlorine, no chemical propellants, and nothing that stains or fades colors, its your houses best friend. Its even been Certified Safe for all carpets, fetching the Seal of Approval by the trusted Carpet and Rug Institute (CRI).
- 100% SATISFACTION GUARANTEED: If your worst stains and odors arent gone, neither is your money. Well give you a full refund, no questions asked.
- Permanently eliminates tough stains and unpleasant odors from urine, feces, vomit, scent markings, dirt, blood and more
- Use on carpets, rugs, pet bedding, upholstery, clothing, curtains, Auto upholstery, litter boxes, crates and carriers, tile, finished wood, laminates, concrete and more
- Uses powerful, natural enzymes to eliminate odors at the source rather than cover them up
- Safe for use around pets
- Eliminates new, old and set-in stains
- EFFECTIVE CLEANING: Safely cleans any hard surface. Multi-Surface is great for walls, floors, granite, cabinets, drawers, countertops, furniture, and many other hard surfaces. Plus, our enzymes remove odors completely, leaving the room smelling fresh and truly clean without strong fragrances.
- HOW IT WORKS: The Pure & Fresh Enzymes break down scum and grime into their basic elements. Multi-Surface provides the longest-lasting results and is safe around children, pets and vegetation.
- ECO-FRIENDLY: Naturally It’s Clean products are safer than harsh chemicals for your home, your pets, and the environment. No harsh fumes, vapors, phosphates, chlorine and petroleum.
- EASY TO USE: Naturally It’s Clean Multi-Surface Cleaner, in two (2) 24oz Ready-To-Use Spray Bottles (total 48oz), is easy to use. Just shake and spray on the affected area, soak, then wipe or scrub away any hard surface. Repeat if necessary.
- MADE IN USA: Our products are produced in our facility in the USA. We are committed to offering the most effective and safest cleaning products for your healthy home and are devoted to a sustainable environment.
- EFFECTIVELY BREAK DOWN CLOGS: Green Gobbler Enzymatic Drain & Grease Trap Cleaner uses natural lipase enzymes to clear buildup and remove odors in grease traps, septic tanks and similar plumbing systems. It helps digests oils, fats, grease, sludge and other food waste within hours of application.
- SAFE FOR PIPES: Green Gobbler helps maintain drain lines, septic tanks, grease traps and grease interceptors. Enzymes are an excellent alternative to Sodium Hydroxide and other caustic chemicals, as Green Gobbler naturally breaks down in the environment.
- IMPROVE GREASE TRAP EFFICIENCY: Green Gobbler increases the efficacy of grease traps by allowing bacteria to work more efficiently to promote the separation of water and grease.
- KEEP SEPTIC TANKS HEALTHY: Green Gobbler helps prompt the biological breakdown of foul odors and organic material inside demanding environments such as drains, pipes and septic tanks.
- MONEY-BACK GUARANTEE: We stand by our products. Green Gobbler is guaranteed or your money back. Simply contact our customer service team if you are unhappy with your results.
- Powerful & All-Natural Odor Eraser: Our Chemical-free formula is a Pet Poop & Pee Smell Destroyer. Not even skunk spray can stand up to Eco Strong’s bioactive potency. Spray it on any outdoor surface, and odors will quickly and permanently disappear. After treating any outdoor area, the only thing left behind will be a fresh Eucalyptus Scent.
- Multi-Surface safe: Our all-natural professional strength formulation contains no harsh chemicals. It will not hurt plants, trees, grass, you, or your pet. Our gentle but super effective formulation will not even affect the color fastness of your artificial turf either. Nasty smells on dirt, driveways, dog runs, gravel, patio furniture, and more are no match for Eco Strong.
- Pet Paw & Barefoot Safe: Our professional strength bio-enzymatic solution is precision balanced to erase organic waste odors at the source (pet urine, poop, etc.) without leaving behind irritating and inflammatory residue. Eco Strong is tough on smells yet soft on the skin.
- A revolution in Oder Treatment Application: With our 2oz Shots and Halo Sprayer Ditch the hose and hassle, now you can quickly and easily treat small areas effectively and rapidly, from apartment balconies, potty areas, your pet’s favorite tree or fence post, and even inside your trash cans with Eco Strong, the smell will be gone.
- Satisfaction Guaranteed: Proudly made in the USA. Eco Strong does not mask foul animal organic scents – it destroys them at the source with powerful bioactive efficiency. Long standing odor problems or newly soiled areas are no match for Eco Strong. Try it risk-free and experience the Eco Strong difference today.
- DUAL ACTION - Our stain remover and pet odor eliminator for home will help you enjoy having your furry friends around without the messes! Our enzyme-active pet carpet cleaner tackles stains, smells, and even pet urine, feces and vomit.
- DESTROY STAINS AND SMELLS - This extremely effective dog urine odor eliminator spray doesn't just mask foul odors and stains, it destroys them upon contact to ensure up to 80 hours of freshness.
- MULTI-SURFACE USE - A versatile odor eliminator and carpet stain remover that can clean it all! This multi-surface enzyme cleaner for dog urine works great on most surfaces, from carpet to hardwood floors, fabric, turf, and more.
- CITRUS SCENT - Made from citrus enzymes and cold-pressed orange oils, this pet stain and odor remover leaves a fruity fragrance behind with every spritz! Safe for both pets and children. (Do not spray directly onto either, though.)
- CUSTOMER SATISFACTION - Add this enzymatic cleaner to the top of your list of pet supplies for dogs and puppies. If you have any questions or concerns about your purchase, reach out to our support team.
- MADE FOR TOUGH ODORS AND ORGANIC STAINS - Simple Solution Extreme Stain and Odor remover is three times stronger than our regular formula to eliminate tough to clean pet stains.
- PROFESSIONAL STRENGTH FORMULA - Extreme Stain and Odor Remover is a professional strength Pro-Bacteria and enzyme formula that breaks down and eliminates both new and old stains and odors.
- SPECIFICALLY FOR DOG AND CAT ODORS AND STAINS - Safely and quickly removes dog and cat urine, feces, and vomit on carpet, upholstery, bedding, fabric toys, clothing, or other water-safe surfaces in your home.
- PATENTED MULTI-FUNCTIONAL SPRAYER - Now designed with a new patented 3-in-1 nozzle sprayer (foam, mist, and stream).
- Certified Gentle And Safe: Chlorine free and color safe. Safe to use around pets and children. No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (cri)
- Eliminates Stains, Odors And Residue: If it’s gross, it’s gone. Not just the stain, but the stink. From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all.
- Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen.
- Enzyme Activated: The key is getting to the problem deep-down. This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated.
- 100% Satisfaction Guaranteed: An Amazon best seller—for a reason. If your stains and odors aren’t gone, neither is your money. We’ll refund it in full.
- YOUR MOP'S NEW BFF: The perfect cleaning companion to your O-Cedar mop bucket is finally here! Concentrated O-Cedar PACS are packed with the deep cleaning power of enzymes to make floor cleaning a breeze.
- PERFECTLY PORTIONED & CONVENIENT: With O-Cedar PACS, you won't have to worry about guessing or making a mess. Simply drop one PAC into 1.6 gallons of water and watch it fizz! Once the bubbles stop, it's time to mop.
- POWERFUL ENZYMES FOR A DEEP CLEAN: O-Cedar PACS use concentrated enzymes that bind to stubborn dirt and grime particles, dissolving them away for a thorough, streak-free clean you can trust.
- NO HARSH CHEMICALS: The formula is made with 97% naturally-derived ingredients and plant-based surfactants that break down dirt and grime, and is gentle on all hard floors. No ammonia, no bleach or parabens.
- TWO REFRESHING SCENTS: O-Cedar Floor Cleaning PACS are available in Crisp Citrus and Lavender scents, leaving your floors smelling fresh and clean.
- SPOT STAIN & ODOR REMOVER: Begins to break down and remove cat stains immediately on contact.
- LIGHT CITRUS SCENT: Cat odor control formula gets your home smelling clean again.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
- TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works.
- SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets.
- DESIGNED FOR CAT MESSES - Simple Solution Cat Extreme Stain and Odor Remover is specifically formulated to eliminate tough cat odors and stains, such as urine, feces, and vomit, while discouraging repeat spraying.
- TRIPLE THE CLEAN- The 3X cleaning formula is specifically designed to remove tough stains and odor from carpets, bedding, fabric, and most water-safe surfaces.
- STRONGER AND BETTER - The professional strength formula of our Simple Solution Cat Extreme Stain & Odor Remover breaks down organic cat messes and is safe around children and pets when used as directed.
- NEW PATENTED MULTI-FUNCTIONAL SPRAYER - Now designed with a new patented 3-in-1 nozzle sprayer (foam, mist, and stream).
- MADE IN THE USA - Simple Solution Cat Extreme Stain and Odor Remover is proudly manufactured in the USA.
- REMOVES PET STAINS- Simple Solution Stain & Odor Remover is formulated to eliminate and neutralize tough dog and cat stains and odors like urine, feces, and vomit
- UNIQUE PRO-BACTERIA FORMULA - This stain and odor remover has a unique Pro-Bacteria and enzyme formula that eliminates stains and odors, and helps prevent repeat marking
- MULTIPLE USES - Safely removes dog and cat stains and odors from carpet, upholstery, bedding, fabric toys, clothing, and other water-safe surfaces in your home
- VERSATILE CLEANING - Our patented 3-in-1 nozzle sprayer gives you more options to tackle stains and odor: stream, foam, or mist
How to choose a good enzyme cleaners
Does the idea of finding a fantastic enzyme cleaners make you anxious? When it comes to purchasing this product, specifically when deciding which model to select, has your head been spinning between options? You are not alone if that is the case. We are aware of the pressure involved in the purchasing process!
Your presence here indicates that you are interested in enzyme cleaners. Before choosing which product would be the best for your needs after being inundated with information, locate a reliable source with genuine selections. You can get that information from a variety of sources, including buying guides and rating websites, word-of-mouth recommendations from friends and family, online discussion forums where users can share their own experiences, product reviews that can be found all over the internet, and YouTube channels. You can only get the right product through exhaustive analysis. But you realize that’s not always simple. In order to ease your concerns, we have taken the time to develop a list of the top enzyme cleaners products available right now. You might be wondering how we came up with the list. How was this buying guide developed?
First, we used our algorithms to gather as much reliable data as we could about these products. To verify all the data gathered, we used both artificial intelligence and a lot of algorithms.
Then, our experts used criteria that are recognized in the business to evaluate them according to their quality to price ratio, allowing us to choose the top enzyme cleaners on the market right now!
The selection of the goods is not arbitrary. Before creating a list, we take into account a number of factors. Below are some of the criteria discussed:
Brand Value: What happens if you choose a dubious brand just because it appears to be a good deal? So the likelihood of receiving a product with a short shelf life increases. That is due to the fact that well-known brands have a reputation to uphold, while others do not. Top enzyme cleaners brands strive to provide some distinctive traits that set them apart from the competition. So, hopefully one or more of the items on our list will be perfect for you.
Features: Useful features are all you need, not tons of them. We consider the important aspects and select the top enzyme cleaners based on those.
Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products with higher specifications, but with the right balance.
Quality: A product’s quality may always be quantified with the aid of numbers. We look for goods with better standards that strike the proper balance. The best quality product that gets highly appreciated and recommended by experienced users.
Customer ratings: Would it be accurate to suggest that the enzyme cleaners were used by hundreds of customers before you? Superior ratings indicate that many customers had better service.
Customer Reviews: Like ratings, provide you with accurate and reliable information about the product from genuine customers. Customer ratings are very important to all of us because they contain accurate and reliable information about the customer service we received from several hundred customers.
Seller Rank: This is very intriguing! Not only do you need a good enzyme cleaners, you also need a product with rising sales that is trendy. It accomplishes two goals. First, the expanding user base proves the quality of the product. Second, given that number, producers must be able to offer greater quality and after-sales support.
Value: You get what you pay for, they say, so consider the value. Cheap isn’t always good and expensive isn’t always bad. However, that does not imply that spending a lot of money on a product that is flashy but underwhelming is a good idea. Before adding them to the list, we make an effort to evaluate how much value you can get for your money from your enzyme cleaners.
Durability: Durability and reliability are closely related concepts. You will benefit from a strong and long-lasting enzyme cleaners for months and years to come.
Product availability: Products come and go, and new ones replace the old ones. Most likely, a few new features and required changes were made. What use is it to use a supposedly good product if the maker no longer supports it? We make an effort to highlight products that are current and offered by one or more trustworthy sellers, if not more.
Negative Reviews: Yes, we do take that into account as well! The goods with the majority of bad reviews are filtered out and disregarded when we choose the best-rated one on the market.
These are the standards by which we selected our enzyme cleaners. Do we end our process there? Hell no. The most crucial fact about us that you should be aware of is that we regularly update our website with current and pertinent information. We have one more layer of filtration since we place the greatest importance on reader satisfaction. Please let us know if any product included here is incorrect, irrelevant, subpar, or simply out of date. We always value your opinions, and we’ll work hard to make any necessary corrections to our list in response to them.
Why should you believe us?
There are now thousands of possibilities for these products on Amazon, but choosing the best one can be difficult and time-consuming. And what enzyme cleaners should you purchase in 2022?
This guide is the result of more than 10 years of experience in researching, testing and writing about many topics. Each member of our team is an authority in their area. We read every article we could find online and every consumer review on every retail website for seven hours. Additionally, we discovered a ton of websites that offered helpful resources, including buying tips and thorough information on enzyme cleaners.
