Are you trying to find enzyme supplement among various brands on the market but aren’t sure where to begin? To assist you in finding the right one, we’ve put together a list of the 7 best to help you pick the perfect one!
We investigated and evaluated a number of the top-selling enzyme supplement on the market in order to create our list of the best. Making a decision among the many options available is never simple. There are an infinite number of models available, each with a distinct price. And as you’ll find out, the best options aren’t usually the ones you imagine! This comparison is rich and relevant because of the numerous factors that were employed. You will find products featured in this ranking not only based on their pricing but also on their features and other customers reviews. To write this review, we completed 24 hours of research and did 27 enzyme supplement tests. You won’t need to pick products at random any more. If you’re unsure of what to look for, browse our list and consult the buying guide!
An overview of our top picks
Table of contents
The best enzyme supplement you can buy today
- SUPPORTS HEALTHY DIGESTION*: NOW Super Enzymes is a comprehensive blend of enzymes that supports healthy digestion.* Take one capsule with a meal.
- Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
- BREAKS DOWN FATS, CARBS, AND PROTEINS*/OPTIMIZES NUTRIENT AVAILABILITY*: Formulated with bromelain, ox bile, pancreatin and papain, Super Enzymes helps to optimize the breakdown of fats, carbohydrates and protein.*
- CERTIFICATIONS/CLASSIFICATIONS: Soy Free, Made without Gluten, Keto Friendly
- GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
- Packaged in the USA by a family owned and operated company since 1968.
- Digestive enzymes are highly specific agents that help transform the food we eat into the nutrition our bodies need.
- Suggested Use: 1 capsule with water at the beginning of each meal (or open capsule and sprinkle over food). Do not sprinkle on hot food. Do not exceed 6 capsules per day
- Well Made Supplement. Contains no yeast, dairy, egg, gluten, corn, soy, or wheat. Contains no sugar, starch, preservatives, or artificial color, flavor, or fragrance.
- Over 40 Years of Trust. Source Naturals was created in 1982 by CEO Ira Goldberg to support everyone’s potential to enjoy optimal health.
- Manufactured in the USA. Manufactured in Scotts Valley, CA, under the Good Manufacturing Practices (cGMPs) established by the US Food and Drug Administration (FDA).
- Digestive Enzymes + Probiotics + Prebiotics: Convenient 3-in-1 gut support solution for relief from occasional bloating, gas, and discomfort from hard-to-digest foods.
- Lab Proven Multi Enzyme Blend: Shown to digest foods up to 39% more completely and 2 hours faster than your body can on its own. Perfect for gluten exposure or Keto and Paleo diets. Lactase, lipase, bromelain, and other enzymes for great digestion.
- Clinically Proven DE111 Probiotic: Guaranteed to arrive alive and work within hours in small intestine where 90% of nutrient absorption occurs.
- Botanical Bounty: Turmeric, Ginger, Green Papaya, Inulin, Apple Pectin, Bladderwrack, Fennel, and Wakame all aid gut health and stomach comfort.
- 60 Count: We suggest taking 1 capsule before your meal or drink to experience digestive delight.
- Get Digestive Comfort Now – Ultra Strength 1000 MG Dose of clinical grade digestive enzymes and a 10 billion CFU 10 strain probiotic with prebiotics. Get results & relief fast with more than double the dose of other digestive enzyme supplements. Using organic, systemic, Dr. formulated, & plant based ingredients to ensure the best healthy digestion for adult men & women. Anti bloating, flatulence, fat, pancreatic, & bowel cleansing with Turmeric, Ginger, Papaya, Pectin, Bladderwrack & more.
- Goodbye Hard-to-Digest Foods – This formula features our Advanced Multi Enzyme System to help you digest fried, spicy, raw, processed food, dairy, protein, salts, carb / carbohydrate, vitamin and acidic diet fruits and veggies. Immune-Boosting Probiotic – The gut, biofilm & gallbladder is home to 50% of the body’s immune repair response and this supplement contains a powerful 10 billion CFU dose of 10 different probiotic strains clinically shown to enhance preventions & immune system response.
- Relieve Gas, Belly Bloating / Bloat, Constipation, Leaky, Indigestion, Reflux, Belching & Acid Discomfort! Aid gut health, beauty & bloated stomach comfort. Prebiotic fiber, probiotic encapsulation(Lactobacillus acidophilus, plantarum, casei, salivarius, bulgaricus and Bifidobacterium lactis, bifidum, breve, longum), & enzymes support gut flora bacteria, bile, nutrient absorption, motility, & enzyme levels your body isn't producing as you age.
- Complete digestive enzyme pills complex blend with essential organic blue agave heart, inulin, amylase / amilasa, papain, protease A, invertase, cellulase, hemicellulase, lactase, lipase / lipasa, alpha-galactosidase, fungal pepsin, glucomylase, & bromelina & bromelain supplement. Plus your probiotic supplement and prebiotic supplement (pre & pro) at the same time. All in a convenient purified cap / capsule form which you can open and take as a chewable with dietary nutrients, super food or meal
- Proudly made in the USA in a GMP certified manufacturing facility, 3rd Party Tested, and a 100% satisfaction money back guarantee. If you are not satisfied with our products for any reason, let us know and we’ll make it right. This product is vegan, non-GMO, pure, natural, gluten free, cGMP, wise, dairy free, zen, organic ingredients and is free of soy, peanuts, eggs, gelatin, ox, shellfish, artificial sweeteners, colors, & flavors.
- COMPLETE GUT WELLNESS: With 15 enzymes plus probiotics and ginger— these veggie capsules are here to promote better nutrient absorption, encourage proper digestion, and help promote stomach regularity*
- HELP EASE STOMACH DIGESTION: Digestive Enzymes from Sports Research is specially formulated to help you digest proteins, fats, fruits, vegetable fiber, dairy products, and carbohydrates, resulting in better nutrient absorption and less digestive discomfort*
- BEAT THE BLOAT: Replenishes enzymes that may decline with age. Our plant-based digestive enzymes with probiotics and ginger work synergistically to help tackle hard-to-digest foods and stomach bloating*
- QUALITY ASSURED: We hold all of our supplements to a higher standard. Rest assured that your digestive enzymes capsules are manufactured in a cGMP-compliant USA facility and third-party tested for quality. Our digestive enzymes capsules are Non-GMO Project Verified, Vegan Certified, and free of gluten, soy, and unwanted fillers
- THE SPORTS RESEARCH DIFFERENCE: Founded in Southern California in 1980, Sports Research is a family-owned business born from a passion for fitness and wellness. Our goal is to embrace the sport of life through research-backed products created for every body—inside and out (Please remove product label before recycling bottle)
- Digestive Enzyme and Prebiotic complex with 240 veggie capsules per bottle, offering a daily dose of 1 capsule for an 8-month supply, featuring a max strength natural proprietary blend.
- Each serving delivers 400mg total, combining 20 enzymes with 5 prebiotics including 200mg of psyllium husk, inulin, acacia senegal, FOS, and chia seed, as well as 200mg of carbs, proteins, fibers, fats, and lactose enzymes.
- Designed for both women and men, this full spectrum blend supports digestion, nutrient absorption, bloating, and overall gut health.
- A synergistic mix that may promote a balanced gut flora, providing daily digestive balance with its unique combination of enzymes and prebiotics.
- Authentic non-GMO digestive enzyme supplement. Contains pure ingredients free of soy, dairy, gluten, wheat, preservatives, eggs, fish, and tree nuts. All products are also 3rd party lab tested for safety and potency.
- Contains All 10 Most Essential Digestive Enzymes: No other digestive enzyme blend contains all 10 most essential digestive enzymes including Amylase, Lipase, Bromelain, Lactase, Papain, Protease, Cellulase, Maltase, Invertase, and Glucoamylase
- Top 3 Pancreatic Enzymes Included: The Amylase pancreatic enzyme breaks down starches and carbohydrates into sugars, the Lipase enzyme lipids, which are fats and oils, into glycerol and fatty acids and protease enzymes break down proteins into amino acids
- VitaZyme Digestive Aid: Double Wood's trademarked digestive enzyme supplement aids digestion and supports overall digestive health. Super enzymes to help with bloating relief
- Breakdown Protein, Fats, and Carbohydrates: Double Wood's Vitazyme blend contains the most essential digestive and pancreatic enzymes needed to breakdown fats, proteins, and carbohydrates
- USA Proud: Doublewood Supplement's VitaZyme Digestive Blend is manufactured and tested for safety right here in the USA, Non-GMO, and Gluten Free
- BREAKS DOWN FATS, CARBS, AND PROTEIN: Super Enzymes is a comprehensive blend of enzymes that supports healthy digestion.*
- OPTIMIZES NUTRIENT AVAILABILITY: Formulated with bromelain, ox bile, pancreatin, and papain, Super Enzymes helps to optimize the breakdown of fats, carbohydrates, and protein.*
- EASY TO SWALLOW TABLET: Supports healthy digestion!*
- GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
- Packaged in the USA by a family owned and operated company since 1968.
- Doctor's Best Proteolytic Enzymes is a potent formulation containing a broad spectrum of proteolytic enzymes (proteases).
- Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
- Proteolytic enzymes function in the body to digest and break down proteins into their amino acid components
- Proteolytic Enzymes Provide Support for Muscle, Joint, and Overall Tissue Health
- Proteolytic Enzymes will appear in clear encapsulation, with no enteric coating and the potency, safety and quality of this product will remain the same
- During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
- DIGESTIVE ENZYMES: Get full spectrum digestive support from a range of enzymes plus probiotics & prebiotics*
- SUPER CONVENIENT: Simply take two capsules before or after meals for maximum support
- ROOTED IN WELLNESS: Carlyle provides premium, honest supplements in your pursuit to healthy living
- CARLYLE MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
- FREE OF: Gluten, Wheat, Soy, Artificial Color, Artificial Flavor, Preservatives & Non-GMO
- Support for Indigestion: Benefits individuals who have occasional indigestion, food sensitivities, gallbladder removal, or who have overused antacids*
- Comprehensive Formula: A blend of hydrochloric acid, pepsin, pancreatin, and ox bile
- Promotes Digestion: Can help ease digestive discomfort that may occur after a meal heavy in fat or red meat, when enjoying foods that cause extra gas and bloating, or when partaking in an occasional overindulgence
- Promotes Nutrient Absorption: Benefits absorption of vitamins, minerals, and other nutrients*
- Trusted: Thorne is trusted by 45,000 health-care professionals and 100+ pro teams and U.S. Olympic teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content
- Beat the Bloat & Say Goodbye to Meal Time Discomfort: 16 beneficial enzymes that digest proteins, carbs, fruits, veggies, beans, dairy, & fats to cover all diets. With SBO Probiotics & Prebiotics to aid digestion further - Your New Meal Time Hack!
- Dual Action Relief: Our powerful digestive enzymes aid with breaking down food while the prebiotics & probiotics promote digestive function in the gut. They work synergistically to provide relief from mealtime discomfort.
- Probiotics that Survive the Gut: Formulated with 3 soil-based probiotic strains - specifically selected due to their ability to survive the harsh gut environment. Along with Organic Prebiotics that fuel the growth of healthy bacteria in the gut.
- Science Backed - Our Digestive Enzyme Probiotics are crafted based on scientific research. We have partnered with expert physicians to help review our products & research. We strive to educate & help you with informed decisions regarding your health.
- Safety Assured Standard of Quality: Our Digestive Enzymes are 3rd-party tested for purity and potency. Each bottle is manufactured with love & care in the USA with strict quality control - using imported and domestic ingredients.
- Probiotics for Women: Our Women’s Daily is rich in digestive enzymes and probiotics to support women’s gut health. Designed exclusively for women, Women’s Daily, is formulated with Cranberry Extract, Biotin, and Vitamin D which focus on the unique nutritional needs of women to promote immune and urinary tract health.
- What it Does: The digestive enzymes in Women’s Daily (Amylase, Lipase, and Protease) work to break down fats, proteins and carbs in food helping to ease digestion. These enzymes also help nutrients get easily absorbed into the body supporting overall health. The probiotics in our formula are combined with essential botanicals making it the perfect supplement for women.
- Say Good-bye to Bloating: Enjoy your favorite foods or indulgent meals without worrying about bloating. The enzymes in Women’s Daily help soothe discomfort and aid in the digestion process to help reduce bloating and relieve gas after a meal.
- How to Use: Take 1 capsule before a meal.
- Create Healthier Habits: With Friska you can optimize your gut health while knowing our supplements are made of a proprietary blend of high-quality ingredients. Our products are made in the USA.
- GENTLE DIGESTIVE SUPPORT: Count on Digestive Ease to be your gentle companion for stomach relief and digestive well-being. It's here to make your meals more enjoyable by addressing common digestive discomforts like indigestion, bloating, gas, and upset stomach from over-indulgence. For best results, take one capsule before every meal.
- SOOTHE WITH NATURE’S HELPERS: We've harnessed the power of natural ingredients in our digestive supplement, including Dandelion Root Extract and Fenugreek Seed blended with magnesium citrate and zinc. These trusted ingredients have a history of soothing stomach discomfort and promoting better digestion.
- 10+ DIGESTIVE ENZYME BLEND: Indulge without the worries of indigestion, malabsorption, and lactose intolerance. Our carefully crafted blend includes 10+ digestive enzymes, each with a unique role in fostering digestive harmony while promoting gas relief and bloating relief.
- PURE & HONEST WELLNESS: Indulge with peace of mind. We don’t hide behind labels so you always know what you are putting into your body. At Stem & Root we believe in a pure and honest approach to your well-being. That’s why our enzymes for digestion contain no artificial colors, flavors, or preservatives. Our digestive supplements are vegan, non-GMO, BSE-free, sulfite-free and gluten-free.
- BACKED BY SCIENCE: At Stem & Root, we believe that solutions for your well-being should stem from nature and be rooted in science. That's why our enzymes for digestion are backed by 13 clinical trials and contain no artificial colors, flavors, or preservatives—just reliable support for your digestive system.
- ESSENTIAL ENZYMES BENEFITS. Expertly formulated compilation of digestive enzymes that break down multiple food groups: carbohydrates, protein, fat and fiber.
- HOW ESSENTIAL ENZYMES WORK. It aids the body’s natural digestive process and helps maximize the body’s utilization of the nutrients in the diet by helping to break down foods into smaller components that can be absorbed.
- SUITABLE FOR VEGETARIANS. Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no sugar, starch, salt, preservatives or artificial color, flavor or fragrance.
- OVER 40 YEARS OF TRUST. Source Naturals was created in 1982 by CEO Ira Goldberg to support each individual's potential to enjoy optimal health.
- MANUFACTURED IN THE USA. Our facility is located in Scotts Valley California.
- SUPPORTS HEALTHY DIGESTION*/VEGAN FORMULA: NOW Plant Enzymes is a comprehensive blend of enzymes that helps to support proper digestion.*
- WITH LACTASE, PROTEASE, PAPIAN, AND BROMELAIN: This product's combination of enzymes assists in the breakdown of fats, fiber, proteins, and carbohydrates, thus optimizing the availability of nutrients in the food you eat.*
- CERTIFICATIONS/CLASSIFICATIONS: Quality GMP Assured, Non-GMO, Soy Free, Vegan/Vegetarian, Kosher, Keto Friendly
- GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
- Packaged in the USA by a family owned and operated company since 1968
- During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
- Chewable Papaya Enzymes are a tasty way to aid in nutrient absorption, increase fat digestion by up to 31%, and digest gluten up to one hour faster for healthy digestion.
- Digestion Relief + Nutrient Absorption: Features papaya powder andan enzyme blend proven to break down hard-to-digest foods, including fats, proteins, carbs, and gluten.
- Lab Proven Enzyme Blend + Natural Papaya: Delicious berry-flavored chews are perfect for pre-or post-meal digestive support. Papayapowder is rich in antioxidants for free radical defense.
- On-The-Go Digestive Support: Bromelain, Protease, and Papain support protein digestion. Glaucomaylse, Amylase, and Diatase tackle carbs. Lipase promotes the digestion of fats.
- 30 SERVING SUPPLY: Includes 1 (30 Count) Zenwise berry flavored Chewable Papaya Enzymes. We suggest 1 chew pre- or post meal.
- More Potent Source Of Digestive Enzymes - If you are looking for a superior digestive enzyme supplement, look no further! Divine Bounty offers one of the most potent, plant based digestive enzyme formulas available for men or women. Our extra strength formula has a powerful 500mg of digestive enzymes in just one capsule, with high activity units.
- Added Prebiotics & Probiotics - We have crafted our formula very carefully. Not only is it one of the most potent digestive enzymes formula, we have taken it a step further and also included prebiotics and probiotics, fortified with 6 essential vitamins. Our multi strain probiotics are 2 Billion total CFU, so you know you're getting high quality ingredients and the best value for money.
- Highest Quality Ingredients - Our formula is made up of only pure ingredients with no harmful additives. Powerful digestive enzymes with only the best probiotics, prebiotics and super vitamins. Don't put other nasty ingredients into your body. Our digestive enzyme capsules are GMO free, soy free, gluten free and have no preservatives, stearates, silicone dioxide or artificial ingredients. Suitable for vegetarian and vegan diets. A pure, clean formula.
- Digestive Enzymes - Our digestive tract plays a very important role in our overall health and wellbeing. That is why we need to look after the delicate balance of digestive enzymes and gut flora in our bodies. Each capsule provides the body with supplementary digestive enzymes, along with pre and pro biotics.
- A Supplement You Can Take With Confidence - Digestive enzymes can also be found in the form of pills, tablets, and powder. But none are as convenient as Divine Bounty capsules. Divine Bounty is proudly made in the USA in an inspected facility. We stand behind our Digestive Enzyme blend and are proud to have the best formula on the market. If it doesn't work for you, let us know. We care about your results. EAN: 9506000122311 09506000122311
- Less Bloating and Discomfort: Relieve bloating with just 2 chewable digestive gummies! Packed with potent enzymes, these treats provide quick relief, leaving you feeling light and confident
- Heat-Resistant Innovation: Our gummies are specially formulated with center-packed enzymes that withstand high temperatures. Enjoy effective digestive support, no matter what's on the menu.
- Sweet Strawberry Joy: Experience natural strawberry flavor in every chew – our gummies are not just a supplement but a delightful fruit snack that makes digestion a pleasure.
- Enzyme Excellence: A powerhouse blend including Lactase, Hemicellulase, Amyloglucosidase, and more ensures efficient digestion of dairy, carbs, fruits, veggies, beans, and proteins for a revitalized you.
- Flamingo Quality, USA Made: Trust Flamingo Quality Assurance – our gummies are proudly made in the USA with the finest ingredients. Elevate your digestive health with confidence and convenience!
- Advanced Prebiotic & Probiotic Blend - Our formula enriches gut health with a balanced mix of prebiotics and probiotics, fostering a healthy digestive ecosystem for optimal nutrient absorption.
- Harmonized Digestive Support - A unified solution that combines powerful enzymes with gut-friendly prebiotics and probiotics, working in tandem for optimal digestion and overall gut wellness.
- Combat Bloating & Discomfort - With over 10 essential enzymes, including Amylase, Lipase, and Protease, to ensure thorough digestive support across all food groups - dairy, fats, proteins, carbs, and fiber. It’s time to eliminate meal time discomfort!
- Herbal Boost For Enhanced Comfort - Our formula features Organic Turmeric, Ginger Root, and a Green Vegetable Blend, known for alleviating stomach discomfort. These botanicals work in harmony to amplify the efficacy of our enzymes and pre and probiotics.
- Boosted Energy & Overall Wellness - Efficient digestion leads to more energy and better overall health. Our formula ensures less energy is spent on digestion, translating to increased vitality and improved well-being.
How to choose a good enzyme supplement
Does the idea of finding a fantastic enzyme supplement make you anxious? When it comes to purchasing this product, specifically when deciding which model to select, has your head been spinning between options? You are not alone if that is the case. We are aware of the pressure involved in the purchasing process!
Your presence here indicates that you are interested in enzyme supplement. Before choosing which product would be the best for your needs after being inundated with information, locate a reliable source with genuine selections. You can get that information from a variety of sources, including buying guides and rating websites, word-of-mouth recommendations from friends and family, online discussion forums where users can share their own experiences, product reviews that can be found all over the internet, and YouTube channels. You can only get the right product through exhaustive analysis. But you realize that’s not always simple. In order to ease your concerns, we have taken the time to develop a list of the top enzyme supplement products available right now. You might be wondering how we came up with the list. How was this buying guide developed?
First, we used our algorithms to gather as much reliable data as we could about these products. To verify all the data gathered, we used both artificial intelligence and a lot of algorithms.
Then, our experts used criteria that are recognized in the business to evaluate them according to their quality to price ratio, allowing us to choose the top enzyme supplement on the market right now!
The selection of the goods is not arbitrary. Before creating a list, we take into account a number of factors. Below are some of the criteria discussed:
Brand Value: What happens if you choose a dubious brand just because it appears to be a good deal? So the likelihood of receiving a product with a short shelf life increases. That is due to the fact that well-known brands have a reputation to uphold, while others do not. Top enzyme supplement brands strive to provide some distinctive traits that set them apart from the competition. So, hopefully one or more of the items on our list will be perfect for you.
Features: Useful features are all you need, not tons of them. We consider the important aspects and select the top enzyme supplement based on those.
Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products with higher specifications, but with the right balance.
Quality: A product’s quality may always be quantified with the aid of numbers. We look for goods with better standards that strike the proper balance. The best quality product that gets highly appreciated and recommended by experienced users.
Customer ratings: Would it be accurate to suggest that the enzyme supplement were used by hundreds of customers before you? Superior ratings indicate that many customers had better service.
Customer Reviews: Like ratings, provide you with accurate and reliable information about the product from genuine customers. Customer ratings are very important to all of us because they contain accurate and reliable information about the customer service we received from several hundred customers.
Seller Rank: This is very intriguing! Not only do you need a good enzyme supplement, you also need a product with rising sales that is trendy. It accomplishes two goals. First, the expanding user base proves the quality of the product. Second, given that number, producers must be able to offer greater quality and after-sales support.
Value: You get what you pay for, they say, so consider the value. Cheap isn’t always good and expensive isn’t always bad. However, that does not imply that spending a lot of money on a product that is flashy but underwhelming is a good idea. Before adding them to the list, we make an effort to evaluate how much value you can get for your money from your enzyme supplement.
Durability: Durability and reliability are closely related concepts. You will benefit from a strong and long-lasting enzyme supplement for months and years to come.
Product availability: Products come and go, and new ones replace the old ones. Most likely, a few new features and required changes were made. What use is it to use a supposedly good product if the maker no longer supports it? We make an effort to highlight products that are current and offered by one or more trustworthy sellers, if not more.
Negative Reviews: Yes, we do take that into account as well! The goods with the majority of bad reviews are filtered out and disregarded when we choose the best-rated one on the market.
These are the standards by which we selected our enzyme supplement. Do we end our process there? Hell no. The most crucial fact about us that you should be aware of is that we regularly update our website with current and pertinent information. We have one more layer of filtration since we place the greatest importance on reader satisfaction. Please let us know if any product included here is incorrect, irrelevant, subpar, or simply out of date. We always value your opinions, and we’ll work hard to make any necessary corrections to our list in response to them.
Why should you believe us?
There are now thousands of possibilities for these products on Amazon, but choosing the best one can be difficult and time-consuming. And what enzyme supplement should you purchase in 2022?
This guide is the result of more than 10 years of experience in researching, testing and writing about many topics. Each member of our team is an authority in their area. We read every article we could find online and every consumer review on every retail website for seven hours. Additionally, we discovered a ton of websites that offered helpful resources, including buying tips and thorough information on enzyme supplement.
