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The 8 Best gas relief medication of 2025

Are you trying to find gas relief medication among various brands on the market but aren’t sure where to begin? To assist you in finding the right one, we’ve put together a list of the 7 best to help you pick the perfect one!

We investigated and evaluated a number of the top-selling gas relief medication on the market in order to create our list of the best. Making a decision among the many options available is never simple. There are an infinite number of models available, each with a distinct price. And as you’ll find out, the best options aren’t usually the ones you imagine! This comparison is rich and relevant because of the numerous factors that were employed. You will find products featured in this ranking not only based on their pricing but also on their features and other customers reviews. To write this review, we completed 13 hours of research and did 67 gas relief medication tests. You won’t need to pick products at random any more. If you’re unsure of what to look for, browse our list and consult the buying guide!

An overview of our top picks

Table of contents

The best gas relief medication you can buy today

SaleNo. 1
Phazyme Maximum Strength Gas & Bloating Relief, Works in Minutes, 24 Fast Gels
  • Phazyme Maximum Strength helps relieve discomfort, bloating and pressure
  • Contains 250 mg Simethicone, the #1 doctor-recommended OTC anti-gas ingredient
  • Goes to work in minutes
  • Easy-to-swallow Fast Gels
  • Contains 1 box of Phazyme Maximum Strength Gas Relief, 24 Fast Gels
SaleNo. 2
Gas-X Extra Strength Chewable Gas Relief Tablets with Simethicone 125 mg for Bloating Relief, Cherry - 72 Count
  • One package of 72 cherry-flavored Gas-X Extra Strength Chewable Gas Relief Tablets with Simethicone 125 mg for bloating and gas relief; number 1 Anti-Gas Relief Brand
  • Gas-X simethicone gas relief tablets relieves gas in minutes and offers bloating relief
  • Gas-X antigas chewable simethicone tablets provides fast gas relief and bloating relief, rescuing you from embarrassing situations and helping you get back to feeling like yourself
  • Contains 125 mg of maximum-strength simethicone for fast relief of gas, bloating and discomfort
  • Simethicone extra strength gas relief tablets are easy to take and come in cherry flavor
  • Gas-X is the number 1 doctor-recommended OTC anti-gas product (1)
  • Adults and children 12 years of age and older may chew one or two gas relief chewable tablets as needed, not to exceed four tablets in 24 hours
  • Gas-X is the name you turn to when you need serious gas relief
  • HSA and FSA eligible product
No. 3
HealthA2Z® Gas Relief Simethicone 180mg | Ultra Strength | Relieves from Stomach Discomfort and Gas | Anti Flatulence | Relieves Gas Fast (120 Count (Pack of 1))
  • HealthA2Z Gas Relief Simethicone Ultra Strength softgels provide fast relief of gas buildup, painful bloating and digestive discomfort of the stomach and intones.
No. 4
Gas-X Maximum Strength Gas Relief Softgels with Simethicone 250 mg for Bloating Relief - 50 Count
  • One 50 ct package of Gas-X Maximum Strength Gas Relief Softgels with Simethicone 250 mg; number 1 Anti-Gas Relief
  • Gas-X simethicone softgels provide fast gas and bloating relief
  • Gas-X antigas provides fast bloating and gas relief, rescuing you from embarrassing situations and helping you get back to feeling like yourself
  • Contains 250 mg of maximum strength simethicone for fast relief of gas, bloating and discomfort - the highest dose available in any over-the-counter antigas pills
  • Simethicone 250 mg gas relief softgels are portable and easy to swallow
  • Gas-X is the number 1 doctor-recommended brand for OTC anti-gas products (1)
  • Adults and children 12 years of age and older may take one or two simethicone gas relief softgels as needed, not to exceed two softgels in 24 hours
  • Gas-X is the name you turn to when you need serious gas relief
SaleNo. 5
HealthA2Z® Gas Relief Simethicone | 125mg | Extra Strength | Relieves from Stomach Discomfort and Gas | Anti Flatulence | Relieves Gas Fast and Bloating (150 Counts (Pack of 1))
  • Active Ingredients: 125mg Simethicone
  • HealthA2Z Simethicone 125mg softgels help to relieve symptoms of extra gas such as belching, bloating, and feelings of pressure/discomfort in the stomach/gut.
  • It helps break up gas bubbles in the gut to provide you with fast relief.
  • Take it after meals or before bedtime for maximum relief.
  • Do not exceed 4 softgels in 24 hours except under the advice and supervision of a physician.
No. 6
Gas-X Maximum Strength Gas Relief Softgels with Simethicone 250 mg - 30 Count
  • One 30 count package of Gas-X Maximum Strength Gas Relief Softgels with Simethicone 250 mg; number 1 Anti-Gas Relief Brand
  • Gas-X simethicone softgels provide fast gas and bloating relief
  • Gas-X antigas goes to work in minutes to provide bloating and gas relief, rescuing you from embarrassing situations and helping you get back to feeling like yourself
  • Contains 250 mg of simethicone—the highest dose available in any over-the-counter antigas pills
  • Simethicone 250 mg gas relief softgels are portable and easy to swallow
  • Gas-X is the number 1 doctor recommended OTC anti-gas product*
  • Adults and children 12 years of age and older may take one or two simethicone gas relief softgels as needed, not to exceed two softgels in 24 hours
  • Gas-X is the name you turn to when you need serious gas relief
  • HSA and FSA eligible product
SaleNo. 7
Maximum Strength Gas Relief Softgels with Simethicone 250 mg Relieve Pressure, Bloating and Painful Discomfort Compare to Gas-X and Phazyme -100 Count
  • ☑️ Compare to active ingredient of major brands.
  • ☑️ Provides fast gas and bloating relief.
  • ☑️ Helps relieve painful pressure caused by excess gas in the stomach and intestines.
  • ☑️ Contains 250 mg of simethicone - compare to a major name brand.
  • ☑️ Adults and children 12 years of age and older may take one or two simethicone gas relief softgels as needed, not to exceed two softgels in 24 hours.
No. 8
Amazon Basic Care Gas Relief Softgels, Simethicone 125 mg, Extra Strength Antigas, 30 Count
  • ACTIVE INGREDIENT: The active ingredient in Amazon Basic Care Gas Relief Softgels is simethicone 125 mg, the #1 doctor recommended anti-gas active ingredient (of U.S. physicians surveyed by an independent market research firm). Compare to the active ingredient in Gas-X.
  • TUMMY TROUBLE? Put the discomfort, pressure and bloating of intestinal gas in the past. Amazon Basic Care Gas Relief Softgels are concentrated to contain an extra-strength dose of liquid gas-fighting medicine in a small softgel so it is easy to swallow with no chalky taste.
  • SIMETHICONE 125 mg is the #1 doctor recommended anti-gas active ingredient (of U.S. physicians surveyed by an independent market research firm). Put this extra strength gas and bloating relief medicine to work for you.
  • SMALL SOFTGELS are easy to swallow, yet still contain an extra strength dose of simethicone, an antigas medicine. A 1- to 2-softgel dose delivers the power to relieve discomfort, pressure and bloating known as gas.
  • GLUTEN FREE: These bloating and gas relief softgels for adults are gluten free and are easy to swallow, with no chalky taste.
SaleNo. 9
Beano Extra Strength, Gas Prevention & Digestive Enzyme Supplement, 100 Count
  • Beano Extra Strength Gas Relief helps prevent gas, bloating and discomfort from harder to digest foods such as beans, vegetables and whole grains
  • Beano gas prevention pills contains a natural enzyme that breaks down complex carbohydrates found in many foods, making them easier to digest to prevent stomach discomfort
  • Clinically proven to help prevent bloating and discomfort
  • For gas and bloating relief, take two antigas tablets within 30 minutes of the meal; tablets are vegetarian friendly
  • This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease
  • Contains 1 pack of Beano Extra Strength Tablets, 100 count
No. 10
HealthA2Z® Gas Relief Simethicone 250mg | Maximum Strength | Fast Gas Relief | Relieve Symptoms Naturally (100 Softgels (Pack of 1))
  • HealthA2Z Gas Relief Simethicone Maximum Strength softgels provide fast relief of gas buildup, painful bloating and digestive discomfort of the stomach and intenstine
  • Goes to work in minutes. Easy-to swallow softgels.
  • Use for relief of pressure, bloating, and fullness commonly referred to as gas.
  • Swallow 1 or 2 softgels as symptoms occur. Do not exceed 2 softgels in 24 hours except under the advice and supervision of a physician.
No. 11
Mylanta Gas Relief Tablets, Gas Minis, Assorted Fruit, 50 Count (Pack of 1)
  • Doctor recommended ingredient for fast gas relief
  • Great tasting mini-tablets
  • Assorted fruit contains 3 different flavors; tropical fruit, cherry, and berry
  • Store at 20-25°C (68-77°F) ; Each dose contains: calcium 75 mg
  • Target gender: unisex
SaleNo. 12
Boiron Gasalia Tablets for Relief from Gas Pressure, Abdominal Pain, Bloating, and Discomfort - 60 Count
  • A homeopathic medicine that works naturally
  • Fast-acting when taken at the onset of symptoms
  • Non-habit forming
  • No side effects, no drug interactions, no contraindications, and no "masking" Of symptoms
  • At Boiron, we believe there’s more than one way to feel better. Since 1932, the Boiron family has been committed to providing quality medicines. As world leader in homeopathy, our passion is your health. Our promise is your satisfaction.
No. 13
Amazon Basic Care Loperamide Hydrochloride 2 mg and Simethicone 125 mg Tablets, Multi-Symptom, Anti-Diarrhea Medicine, Gas Relief, 24 Count
2,634 Consomer Reviews
Amazon Basic Care Loperamide Hydrochloride 2 mg and Simethicone 125 mg Tablets, Multi-Symptom, Anti-Diarrhea Medicine, Gas Relief, 24 Count
  • ACTIVE INGREDIENTS: This product contains loperamide hydrochloride 2 mg, anti-diarrheal, and simethicone 125 mg, anti-gas, which compares to the active ingredients of Imodium Multi-Symptom Relief.
  • MULTI-SYMPTOM RELIEF: This anti-diarrheal and anti-gas medicine relieves symptoms of diarrhea plus bloating, pressure and cramps, commonly referred to as gas.
  • WHAT IS DIARRHEA: Diarrhea is a loose and watery bowel movement and very common as many people may have it once or twice a year. Usually not serious, it will typically last two or three days and is normally treated with an over-the-counter medication.
  • DIARRHEA FACT: Properly washing hands can help eliminate the spread of infection that causes a serious type of diarrhea.
  • HELP PREVENT DEHYDRATION: Drink plenty of clear fluids to help prevent dehydration caused by diarrhea.
No. 14
NUVICARE Extra Strength Gas Relief - Simethicone 125mg Softgels - Fast Anti Gas Bloating Relief - Compare to The Active Ingredient in Gas-X Anti Gas Pills - Stomach Gas Relief for Adults (100 Count)
  • GENTLE EVERYDAY GAS RELIEF - When gas discomfort hits, it leaves you feeling sluggish and weighed down. Nuvicare Extra Strength Gas Relief softgels are here to help you ease into comfort again. With 125 mg of Simethicone, this OTC gas medicine provides gentle daily relief.
  • COMPARE TO THE ACTIVE INGREDIENT IN GAS - You don’t have to spend more for the relief you deserve. Nuvicare offers the same active ingredient as leading brands, without the higher price tag. Each softgel dose contains 125 mg of anti-gas Simethicone.
  • RELIEVES GAS, BLOATING & PRESSURE - Feeling bloated and full makes even the simplest tasks uncomfortable. Reduce symptoms by taking one (1) or two (2) anti gas pills for extra-strength indigestion relief, severe bloat relief, or regular gas & bloating relief in women and men.
  • 125MG FAST-ACTING FOR ON THE GO - Life doesn’t stop because of gas pain. These abdominal gas relief pills work fast to relieve gas and bloating, so you can get back to your routine without feeling held back. Keep them close by for quick relief when you need it.
  • HANDY WHEN YOU'RE IN A RUSH - Don’t let pain or pressure slow you down. Our softgels are designed for easy swallowing and quick absorption, ideal for fast relief during busy days. The bottle is compact and discreet, slip one into your bag or keep one in the car for whenever bloating and pressure strike.
No. 15
Gas-X Extra Strength Chewable Gas Relief Tablets with Simethicone 125 mg, Peppermint Creme - 18 Count
  • One 18 count package of peppermint creme flavored Gas-X Extra Strength Chewable Gas Relief Tablets with Simethicone 125 mg; number 1 Anti-Gas Relief Brand
  • Gas-X simethicone gas relief tablets provide fast gas and bloating relief
  • Gas-X antigas chewable simethicone tablets go to work in minutes to provide bloating and gas relief, rescuing you from embarrassing situations and helping you get back to feeling like yourself
  • Contains 125 mg of simethicone for fast gas relief
  • Simethicone extra strength gas relief tablets are easy to take and come in delicious peppermint creme flavor
  • Gas-X is the number one recommended gas relief brand from doctors
  • Adults and children 12 years of age and older may chew one or two gas relief chewable tablets as needed, not to exceed four tablets in 24 hours
  • Gas-X is the name you turn to when you need serious gas relief
  • HSA and FSA eligible product
SaleNo. 16
Gas-X Extra Strength Gas Relief Softgels with Simethicone 125 mg for Bloating Relief - 72 Count
  • One 72 ct package of Gas-X Extra Strength Gas Relief Softgels with Simethicone 125 mg; number 1 Anti-Gas Relief Brand
  • Gas-X simethicone gas relief softgels provide fast gas and bloating relief
  • Gas-X antigas simethicone softgels relieve gas in minutes to provide bloating and gas relief, rescuing you from embarrassing situations and helping you get back to feeling like yourself
  • Antigas pills contain 125 mg of simethicone for fast gas relief
  • Simethicone extra strength gas relief softgels are easy to take
  • Gas-X is the number 1 doctor-recommended brand for OTC anti-gas products (1)
  • Adults and children 12 years of age and older may take one or two bloating and gas relief pills as needed, not to exceed four softgels in 24 hours
  • Gas-X is the name you turn to when you need serious gas relief
SaleNo. 17
Zenwise Health NO Bloat - Probiotics for Digestive Health with Ginger, Dandelion, and Lactase, Digestive Enzymes for Gas and Bloating Relief for Women and Men - Vegan Water Retention Pills - 60 Count
  • Banish Indigestion: Fast relief with digestive enzymes, clinically proven probiotics, and organic botanicals which offer support for bloating and gas.
  • Gut Love Starts with Enzymes: Multi Enzyme Blend helps break down hard-to-digest food and alcohol to help ease water retention, bloating, gas, and digestive woes.
  • Clinically Proven Probiotic: Guaranteed to survive passage through to the small intestine where it helps support digestive balance.
  • Organic Digestive Botanical Blend: Includes such herbs and greens as Turmeric, Ginger, Dandelion Extract, Fennel Seed Powder, and Cinnamon extract for a happy, healthy GI tract.
  • 60 Count: We suggest taking 2 capsules after each meal or drink for bloating and gas relief.
No. 18
NUVICARE Ultra Strength Gas Relief - Simethicone 180mg Softgels - Anti Gas and Bloating Relief - Compare to The Active Ingredient in Phazyme Anti Gas Pills - Stomach Gas Relief for Adults (100 Count)
  • ULTRA STRENGTH GAS RELIEF - When gas strikes hard, it can ruin your day... leaving you feeling bloated, heavy, and uncomfortable. These gas relief maximum strength softgels deliver fast, powerful relief with 180 mg of Simethicone, helping you break through the discomfort and get back to living life.
  • COMPARE TO THE ACTIVE INGREDIENT IN PHAZYM - Why struggle with expensive brands when Nuvicare offers the same active ingredient at a better value? Each softgel contains anti-gas Simethicone (180 mg), the same strength as popular brands from the pharmacy, at budget-friendly price.
  • RELIEVES BLOATING, PRESSURE & FULLNESS - Feeling uncomfortably full, bloated, or under pressure? Soothe symptoms by taking one (1) or two (2) anti gas pills for extra-strength indigestion relief, severe bloat relief, or regular gas & bloating relief in women and men.
  • 180MG FAST-ACTING FOR ANTI-FLATULENCE - Gas discomfort can hit suddenly and without warning. Our abdominal gas relief pills deliver fast-acting support, helping you feel better quickly when gas causes pain and pressure. Don’t let bloating take over your day... relief is just a softgel away.
  • CONVENIENT WHEN YOU'RE IN A HURRY - When gas discomfort comes knocking at the back door, you don’t want to struggle to find a solution. Our easy-to-swallow softgels are small and super convenient, delivering fast absorption to provide the relief you need, right when you need it.
SaleNo. 19
Imodium Multi-Symptom Relief Caplets with Loperamide Hydrochloride and Simethicone, Anti-Diarrheal Medicine for Treatment of Diarrhea, Gas, Bloating, Cramps & Pressure, 24 ct.
  • 24-count package of Imodium Multi-Symptom Relief Caplets with loperamide HCl and simethicone for effective relief of diarrhea and other abdominal-related symptoms
  • Imodium Multi-Symptom Relief is the only branded product that provides diarrhea relief while also helping to alleviate abdominal symptoms by working with your body to slow down your system and restore its natural rhythm and balance
  • Each caplet of diarrhea medicine contains 2 mg of loperamide hydrochloride for acute diarrhea relief and 125 mg of simethicone to help treat symptoms associated with gas-related abdominal discomfort including bloating, pressure, gas and cramps
  • No other branded anti-diarrheal medicine combines the two powerful ingredients of loperamide HCl and simethicone for multi-symptom relief
  • Brand of anti-diarrheals, these medicine caplets are suitable for use by adults and children ages 12 and older for effective diarrhea relief, both at home and on-the-go
No. 20
GenCare -Extra Strength Gas Relief Simethicone 125mg (180 Softgels) Maximum Strength Anti Gas Pills for Bloating Relief, Pressure & Discomfort - Compare to Generic Extra Strength Gas X
  • EXTRA STRENGTH - Each easy to swallow soft gel contains 125mg of Simethicone active ingredient (Compare to Generic Gas X) to relieve gas fast. Use as relief for pressure, bloating, and fullness commonly referred to as gas.
  • HUGE SAVINGS – You’ll love the convenience of stocking up and saving big with our 180 count value bottle. Get extra strength gas relief at a family friendly price compared to your local pharmacy and big box retailer. Store at 59-86 degrees Fahrenheit (15-30 degrees Celsius).
  • FAST GAS RELIEF – Help relieve and alleviate painful gas and bloating as symptoms occur. GenCare Extra Strength Gas Relief Simethicone starts working in minutes as an anti foaming agent to treat the effects of stomach gas buildup naturally and safely.
  • DIRECTIONS – Adults: swallow with water 1 or 2 softgels as needed after meals and at bedtime. Do not exceed 4 softgels in 24 hours except under the advice and supervision of a physician.
  • 100% SATISFACTION GUARANTEE - We know you and your family will love the ultimate convenience of our 180 count bulk savings bottle. That's why we back up each tamper proof bottle with our 100% Satisfaction Guarantee. Join thousands of gas relief customers with GenCare Extra Strength Gas Relief Simethicone.

How to choose a good gas relief medication

Does the idea of finding a fantastic gas relief medication make you anxious? When it comes to purchasing this product, specifically when deciding which model to select, has your head been spinning between options? You are not alone if that is the case. We are aware of the pressure involved in the purchasing process!

Your presence here indicates that you are interested in gas relief medication. Before choosing which product would be the best for your needs after being inundated with information, locate a reliable source with genuine selections. You can get that information from a variety of sources, including buying guides and rating websites, word-of-mouth recommendations from friends and family, online discussion forums where users can share their own experiences, product reviews that can be found all over the internet, and YouTube channels. You can only get the right product through exhaustive analysis. But you realize that’s not always simple. In order to ease your concerns, we have taken the time to develop a list of the top gas relief medication products available right now. You might be wondering how we came up with the list. How was this buying guide developed?

First, we used our algorithms to gather as much reliable data as we could about these products. To verify all the data gathered, we used both artificial intelligence and a lot of algorithms.
Then, our experts used criteria that are recognized in the business to evaluate them according to their quality to price ratio, allowing us to choose the top gas relief medication on the market right now!

The selection of the goods is not arbitrary. Before creating a list, we take into account a number of factors. Below are some of the criteria discussed:

Brand Value: What happens if you choose a dubious brand just because it appears to be a good deal? So the likelihood of receiving a product with a short shelf life increases. That is due to the fact that well-known brands have a reputation to uphold, while others do not. Top gas relief medication brands strive to provide some distinctive traits that set them apart from the competition. So, hopefully one or more of the items on our list will be perfect for you.

Features: Useful features are all you need, not tons of them. We consider the important aspects and select the top gas relief medication based on those.

Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products with higher specifications, but with the right balance.

Quality: A product’s quality may always be quantified with the aid of numbers. We look for goods with better standards that strike the proper balance. The best quality product that gets highly appreciated and recommended by experienced users.

Customer ratings:  Would it be accurate to suggest that the gas relief medication were used by hundreds of customers before you? Superior ratings indicate that many customers had better service.

Customer Reviews: Like ratings,  provide you with accurate and reliable information about the product from genuine customers. Customer ratings are very important to all of us because they contain accurate and reliable information about the customer service we received from several hundred customers.

Seller Rank: This is very intriguing! Not only do you need a good gas relief medication, you also need a product with rising sales that is trendy. It accomplishes two goals. First, the expanding user base proves the quality of the product. Second, given that number, producers must be able to offer greater quality and after-sales support.

Value: You get what you pay for, they say, so consider the value. Cheap isn’t always good and expensive isn’t always bad. However, that does not imply that spending a lot of money on a product that is flashy but underwhelming is a good idea. Before adding them to the list, we make an effort to evaluate how much value you can get for your money from your gas relief medication.

Durability: Durability and reliability are closely related concepts. You will benefit from a strong and long-lasting gas relief medication for months and years to come.

Product availability: Products come and go, and new ones replace the old ones. Most likely, a few new features and required changes were made. What use is it to use a supposedly good product if the maker no longer supports it? We make an effort to highlight products that are current and offered by one or more trustworthy sellers, if not more.

Negative Reviews: Yes, we do take that into account as well! The goods with the majority of bad reviews are filtered out and disregarded when we choose the best-rated one on the market.

These are the standards by which we selected our gas relief medication. Do we end our process there? Hell no. The most crucial fact about us that you should be aware of is that we regularly update our website with current and pertinent information. We have one more layer of filtration since we place the greatest importance on reader satisfaction. Please let us know if any product included here is incorrect, irrelevant, subpar, or simply out of date. We always value your opinions, and we’ll work hard to make any necessary corrections to our list in response to them.

Why should you believe us?

There are now thousands of possibilities for these products on Amazon, but choosing the best one can be difficult and time-consuming. And what gas relief medication should you purchase in 2022?

This guide is the result of more than 10 years of experience in researching, testing and writing about many topics. Each member of our team is an authority in their area. We read every article we could find online and every consumer review on every retail website for seven hours. Additionally, we discovered a ton of websites that offered helpful resources, including buying tips and thorough information on gas relief medication.