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The 8 Best medical skin protectants barrier creams of 2024

Are you trying to find medical skin protectants barrier creams among various brands on the market but aren’t sure where to begin? To assist you in finding the right one, we’ve put together a list of the 7 best to help you pick the perfect one!

We investigated and evaluated a number of the top-selling medical skin protectants barrier creams on the market in order to create our list of the best. Making a decision among the many options available is never simple. There are an infinite number of models available, each with a distinct price. And as you’ll find out, the best options aren’t usually the ones you imagine! This comparison is rich and relevant because of the numerous factors that were employed. You will find products featured in this ranking not only based on their pricing but also on their features and other customers reviews. To write this review, we completed 22 hours of research and did 35 medical skin protectants barrier creams tests. You won’t need to pick products at random any more. If you’re unsure of what to look for, browse our list and consult the buying guide!

An overview of our top picks

Table of contents

The best medical skin protectants barrier creams you can buy today

SaleNo. 1
Dynarex Dyna Shield Skin Protectant Barrier Cream Tube, 0.29 Pound
  • Incontinence
  • Dyna Shield Skin Protectant Barrier Cream 4 oz. Tube
  • Made in: United States
  • Dyna shield skin protectant barrier cream 4 oz tube
SaleNo. 2
PeriGuard Skin Protectant Ointment - Vitamin A, D, E, Aloe Vera, Zinc, Petroleum Based Moisture Barrier – 2 Tubes, 7 oz Each
  • TRUSTED CARE: DermaRite has been providing cost-effective, dependable skin and wound care products for over 25 years.
  • TREAT AND PROTECT: Use PeriGuard to treat or prevent rashes and skin irritation associated with moisture and incontinence and seal out wetness.
  • GENTLE SKIN PROTECTION: Mild enough for everyday use. Dries clear with no heavy residue and comes off easily even from sensitive skin.
  • NOURISHING FORMULA: Contains aloe vera and vitamins A, D and E to nourish, moisturize and protect skin. PeriGuard ointment leaves your skin soft and supple.
No. 3
DermaRite Lantiseptic Moisture Shield Original Skin Protectant – 50% Lanolin Enriched Skin Protectant Barrier Cream for Incontinence – Paraben Free, 2 Jars, 4.5oz Each
  • FROM THE TRUSTED EXPERTS IN LANOLIN-BASED SKIN CARE: Lantiseptic has been a favorite of professionals and patients for over 20 years.
  • TREATS AND PREVENTS: Lantiseptic Moisture Shield helps relieve and prevent rashes and irritation due to wetness from incontinence, prevents chafed skin due to irritation, and helps seal out wetness.
  • NOURISHES FOR HEALTHIER SKIN: Lanolin encourages proper moisture balance to support skin health and boost the body’s natural healing abilities.
  • PREFERRED, NATURALLY DERIVED ACTIVE INGREDIENT: Lanolin, the active ingredient in Lantiseptic Moisture Shield, closely mimics human skin lipids, is naturally derived from sheep’s wool, and has been used for thousands of years to improve skin quality.
  • PARABEN-FREE
SaleNo. 4
Dynarex DynaShield Skin Protectant Barrier Cream - Zinc Oxide Cream with Vitamins A, D, E, Aloe Vera - Protective Ointment, Helps Moisturize Dry Skin - 4oz Tube, 24 Per Case
  • Fight Itch & Irritation - Is uncomfortable chafing or dryness keeping you or someone in your care awake? Our diaper cream may help restore the moisture barrier and keep rashes from forming.
  • Enriched Formula - A zinc-oxide-based diaper rash cream, it's infused with vitamins A, D, and E, plus hydrating aloe vera. It acts as a moisture barrier to help seal out wetness and cushion the skin.
  • Lasting Comfort - This zinc oxide ointment for adults has a pleasant fragrance and a non-greasy formula easily absorbed by the skin, leaving no residue. It may be used to dry oozing from an oak or ivy rash.
  • Ready to Use - This barrier cream for incontinence comes in 16oz jars or 4oz squeeze tubes with flip-top caps for easy application. A variant with dimethicone is available for cracked, flaky skin.
  • A Versatile Solution - The rash cream for adults doesn't contain natural rubber latex - suited for sensitive, irritation-prone skin. A case contains either 12 jars or 24 tubes of skin barrier cream in bulk.
No. 5
Medline Remedy Essentials Zinc Oxide Skin Protectant Paste (4 oz Tube), Unscented, Barrier, Incontinence Cream, Diaper Rash, Adults, Elderly, Hypoallergenic, Paraben Free
  • EFFECTIVE WETNESS DEFENSE: New packaging, same great product. Thick paste contains 75% petrolatum and 20% zinc oxide to form a dense layer of protection on damaged skin or rash caused by heat, chafing, sweat and incontinence
  • LASTING PROTECTION: Barrier that protects intact and skin irritated by prolonged exposure to wetness, helping prevent or treat diaper rash and incontinence-related skin damage and discomfort
  • TEMPORARILY PROTECTS AND SOOTHES: Extremely versatile use in soothing and protecting aged, chafed, itchy and bedridden skin; as well as minor cuts, scrapes and burns
  • EXTRA GENTLE: Hypoallergenic, suitable for users with sensitive skin; fragrance free with no dyes, alcohol, parabens, aloe or phthalates
  • HEALTHCARE PROVEN: Created for at-risk skin, proven in hospitals and long-term care facilities nationwide, and now available to everyone seeking high-level skin care
SaleNo. 6
Chamosyn-SC0125W Moisture Barrier Ointment Skin Protectant with Aloe, Chamomile & Manuka Honey 4 oz Tube - Pack of 2
  • Chamosyn temporarily protects and soothes irritated or chafed skin caused by the following.
  • Diaper rash, hemorrhoids, perspiration
  • Urine and fecal incontinence, fecal or vaginal fistulas
  • Feeding tube leakage
  • Wound Drainage, minor burns, cuts, and scrapes
No. 7
NormlShield Skin Protectant Barrier Cream 4oz Tube
  • Sold by the Tube
  • Quantity per Tube : 1 EA
  • Category : Creams & Ointments
  • Product Class : Self Care
SaleNo. 8
TriDerma Protect & Heal Non-Greasy Moisture Barrier Skin Protectant Incontinence Cream for Adult Diaper Rash, Chafing, Redness, Sensitive Skin with Dimethicone, Aloe Vera, FSA Eligible 4 oz
  • FSA HSA APPROVED diaper cream for incontinence seals out wetness, relieves redness, soothes irritated or cracked skin. Helps protect against skin breakdown with two clinically proven skin protectants
  • ADVANCED MOISTURE BARRIER healing and chafing cream protects against chapped or chafed skin from adult diapers, skin folds, incontinence underwear and cloth diapers. It's compatible with adult wipes.
  • DERMATOLOGIST TESTED long-lasting diaper rash cream spreads easily on skin and makes clean-up a breeze. Easy to apply, easy to wipe off, not sticky or gooey like a zinc oxide ointment.
  • FRAGILE, SENSITIVE SKIN CREAMY OINTMENT contains proprietary AP4 Aloe Vera Complex, Allantoin, Dimethicone, Beeswax, soothing Oat Extract, Shea Butter, Vitamins, Fragrance Free, No Parabens
  • WOMEN OWNED TriDerma MD has been helping people heal skin irritations since 1992. Our maximum strength skin healing products are Made in the USA with natural ingredients and proven actives for rapid skin relief.
No. 9
Medline Remedy Essentials Skin Barrier Protectant Ointment, Hypoallergenic, Fragrance-Free, 2-oz Tube (Pack of 12)
26 Consomer Reviews
Medline Remedy Essentials Skin Barrier Protectant Ointment, Hypoallergenic, Fragrance-Free, 2-oz Tube (Pack of 12)
  • Carefully formulated to provide exceptional, economical everyday care
  • Petrolatum content helps create a reliable barrier that moisturizes and nourishes as it protects
  • Long-lasting protection against the harmful effects of incontinence
  • Can help maintain the skin's natural barrier function
  • Hypoallergenic, paraben-free, CHG compatible and fragrance-free safe for use on skin of all ages
SaleNo. 10
Dermarite PeriGuard Skin Protectant Ointment, 2 Pack - 3.5 oz Tube - With Vitamins A, D, E, Aloe Vera and Zinc - Clear Moisture Barrier Cream
  • PREMIUM SKIN PROTECTION: PeriGuard ointment leaves your skin soft and supple. It goes on clear, does not leave heavy residue, and comes off super easily even from sensitive skin.
  • ALL NATURAL FORMULA: A petrolatum-based skin barrier cream, it is infused with zinc, vitamins A, D and E and lanolin to nourish, moisturize and heal skin.
  • MULTI USE: Use PeriGuard to treat skin irritations associated with wetness and incontinence or as part of a comprehensive prevention program. Prevent and treat adult diaper rash, as well as bed sores, pressure ulcers, dry skin, chafing, burns and other rashes, conditions and irritation.
  • PREVENTS SKIN BREAKDOWN: This protective adult diaper rash cream prevents possible skin breakdown that may occur as a result of incontinence. This clear moisture barrier ointment locks wetness in and treats chafing effectively.
  • DERMATOLOGIST TESTED: PeriGuard is the trusted name you've seen in hospitals and medical facilities. The doctor recommended paste is tried and tested.
No. 11
Dynarex CalaSoothe Skin Protectant Moisture Barrier Cream - Anti Itch Cream with 20% Zinc Oxide & 0.4% Menthol for Relief of Dryness, Itching, Rash, Minor Burns, Wound Care - 4 oz. Tubes, 1 Count
  • Get Immediate Relief - Our anti itch lotion contains 20% zinc oxide and 4% menthol which work together to provide instant-contact relief from pain and itching caused by rashes, wounds, bites, and burns.
  • Helps Protect The Skin - Our skin protectant barrier cream also contains calamine lotion and lanolin which helps reduce skin weeping and dryness, and creates a protective moisture barrier on the skin.
  • Wide Range of Uses - Aside from bites, rashes, burns, and wounds, our zinc oxide cream is also great for periwound skin and irritations caused by urine, diarrhea, perspiration, and fistula drainage.
  • Packaged For Your Convenience - This skin barrier cream is available in small packets of 3.5g and large 4 oz. tubes. Have a few packets ready in your baby bag or first aid kit, and a tube at home!
  • Great For Hospitals & Medical Facilities - Our anti-itch cream can be bought in bulk, making it ideal for use in hospitals, clinics, nursing homes, healthcare facilities, schools, and other institutions.
No. 12
Munchkin® HYP03™ No Rub Daily Diaper Rash Spray with Hypochlorous, Award Winning, Removes Rash Causing Germs, Easy Application vs. Messy Creams, 100% Natural, 600 Sprays
  • 2023 NAPPA Award Winner! Named one of the best products for “Baby and New Mom” and is a finalist for the 2023 JPMA Innovation Awards
  • Zinc-Free: Other diaper rash products just cover up diaper rash. HYP03 harnesses the power of Hypochlorous, a naturally occurring ingredient used by your white blood cells, to remove bacteria causing diaper rash from your skin.
  • Ick-Free: Unlike other Diaper Rash products, HYP03 doesn't use zinc or creams that get messy and that you have to wipe off. Just spray. No need to rub-in or to rinse off. Dries without leaving residue.
  • Sting-Free: Cleans inflamed bottoms without added pain. Spray on your baby's most sensitive areas.
  • Stink-Free: Effectively removes odor-causing bacteria and germs. HYP03 is not scented and leaves no odor.
  • Gentle and safe for everyday use. Because Daily Diaper Rash Spray is steroid-free you can use it several times a day without worry.
  • Each bottle has over 600 sprays and is made in the USA
No. 13
TriDerma MD Extreme Dryness PLUS Therapeutic Relief Cream for Dry Skin, Chapped, Cracked Hands, Non-Greasy and Fragrance Free, 2.2 Ounces
15 Consomer Reviews
TriDerma MD Extreme Dryness PLUS Therapeutic Relief Cream for Dry Skin, Chapped, Cracked Hands, Non-Greasy and Fragrance Free, 2.2 Ounces
  • Concentrated hand cream for extreme dry, cracked hands and body.
  • Contains two proven skin protectants
No. 14
Medline Remedy Olivamine 4 Ounce Calazime Skin Protectant Paste Cream, used with dry chapped skin from diaper rash, incontinence, dermatitis, psoriasis, burns, bites, or rash
  • Calazime dries light exudates from compromised skin
  • Nourishes skin, helps treat and prevent diaper rash, wet and cracked skin
  • Menthol cools irritated skin and calms inflamed tissue
  • Nourishes skin with amino acids, antioxidants and pain control ingredients
  • Non-allergenic and non-sensitizing
SaleNo. 15
No. 16
Medline - MSC095420 Soothe and Cool Inzo Barrier Cream, 4 Ounce
  • Skin Care products/Skin Protectants
  • Composed of vitamins A, D and E meant for nourishing the skin
  • Allows skin to breathe without beingn occlusive
  • Ideal for use under tape
No. 17
Lantiseptic Moisture Shield Original Skin Protectant – 50% Lanolin Enriched Skin Protectant Barrier Cream for Incontinence – Paraben Free, 3 Jars, 12oz Each
  • FROM THE TRUSTED EXPERTS IN LANOLIN-BASED SKIN CARE: Lantiseptic has been a favorite of professionals and patients for over 20 years.
  • TREATS AND PREVENTS: Lantiseptic Moisture Shield helps relieve and prevent rashes and irritation due to wetness from incontinence, prevents chafed skin due to irritation, and helps seal out wetness.
  • NOURISHES FOR HEALTHIER SKIN: Lanolin encourages proper moisture balance to support skin health and boost the body’s natural healing abilities.
  • PREFERRED, NATURALLY DERIVED ACTIVE INGREDIENT: Lanolin, the active ingredient in Lantiseptic Moisture Shield, closely mimics human skin lipids, is naturally derived from sheep’s wool, and has been used for thousands of years to improve skin quality.
  • PARABEN-FREE
No. 18
Lantiseptic Moisture Shield Original Skin Protectant – 50% Lanolin Enriched Skin Protectant Barrier Cream for Incontinence – Paraben Free, 1 Jar, 12oz
  • FROM THE TRUSTED EXPERTS IN LANOLIN-BASED SKIN CARE: Lantiseptic has been a favorite of professionals and patients for over 20 years.
  • TREATS AND PREVENTS: Lantiseptic Moisture Shield helps relieve and prevent rashes and irritation due to wetness from incontinence, prevents chafed skin due to irritation, and helps seal out wetness.
  • NOURISHES FOR HEALTHIER SKIN: Lanolin encourages proper moisture balance to support skin health and boost the body’s natural healing abilities.
  • PREFERRED, NATURALLY DERIVED ACTIVE INGREDIENT: Lanolin, the active ingredient in Lantiseptic Moisture Shield, closely mimics human skin lipids, is naturally derived from sheep’s wool, and has been used for thousands of years to improve skin quality.
  • This offering is for 1 resealable jar, 12 ounces.
SaleNo. 19
TriDerma Botanisept™ Barrier Cream, Multi-Purpose Moisture Barrier for Incontinence, Diaper Rash, Irritated Skin, Helps Relieve Discomfort and Itching 4 oz
  • Helps heal and prevent diaper rash, chafed skin and incontinence.
  • Menthol and Calamine help soothe skin.
  • Allantoin, Vitamins B & E help heal and soothe skin.
  • Non-Greasy, Fragrance-free, Non-Sticky, Paraben-free.
SaleNo. 20
Medline Remedy CLINICAL Zinc Oxide Paste Skin Protectant (4 oz Tube), Vanilla Scent, Diaper Rash Cream, Incontinence Care, Wetness Protection, Paraben Free, Hypoallergenic, Adults, Children
  • HIGH LEVEL SKIN PROTECTION: New name, same great product. Formerly called Phytoplex Z-Guard, this protectant paste is effective for diaper rash or extremely fragile skin, helping treat & prevent skin breakdown caused by prolonged exposure to wetness
  • EFFECTIVE WETNESS PROTECTION: 57% white petrolatum helps seal out wetness; 17% micronized zinc oxide and natural oils provide a smooth texture that’s easy to apply and remove
  • MANY USES: Great for all ages—including the elderly; also protects and soothes irritations like chapped or cracked skin, minor cuts, scrapes and burns
  • ADVANCED SKIN SUPPORT: Gentle, hypoallergenic and fortified with Remedy Nutrient Complex (formerly called Phytoplex) which provides extra skin nutrition, moisturization and antioxidants for a soothing layer of nourishing protection
  • HEALTHCARE PROVEN: Created for sensitive skin and proven in healthcare facilities nationwide; hypoallergenic; no fragrance, dye, alcohol, parabens, aloe or phthalates

How to choose a good medical skin protectants barrier creams

Does the idea of finding a fantastic medical skin protectants barrier creams make you anxious? When it comes to purchasing this product, specifically when deciding which model to select, has your head been spinning between options? You are not alone if that is the case. We are aware of the pressure involved in the purchasing process!

Your presence here indicates that you are interested in medical skin protectants barrier creams. Before choosing which product would be the best for your needs after being inundated with information, locate a reliable source with genuine selections. You can get that information from a variety of sources, including buying guides and rating websites, word-of-mouth recommendations from friends and family, online discussion forums where users can share their own experiences, product reviews that can be found all over the internet, and YouTube channels. You can only get the right product through exhaustive analysis. But you realize that’s not always simple. In order to ease your concerns, we have taken the time to develop a list of the top medical skin protectants barrier creams products available right now. You might be wondering how we came up with the list. How was this buying guide developed?

First, we used our algorithms to gather as much reliable data as we could about these products. To verify all the data gathered, we used both artificial intelligence and a lot of algorithms.
Then, our experts used criteria that are recognized in the business to evaluate them according to their quality to price ratio, allowing us to choose the top medical skin protectants barrier creams on the market right now!

The selection of the goods is not arbitrary. Before creating a list, we take into account a number of factors. Below are some of the criteria discussed:

Brand Value: What happens if you choose a dubious brand just because it appears to be a good deal? So the likelihood of receiving a product with a short shelf life increases. That is due to the fact that well-known brands have a reputation to uphold, while others do not. Top medical skin protectants barrier creams brands strive to provide some distinctive traits that set them apart from the competition. So, hopefully one or more of the items on our list will be perfect for you.

Features: Useful features are all you need, not tons of them. We consider the important aspects and select the top medical skin protectants barrier creams based on those.

Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products with higher specifications, but with the right balance.

Quality: A product’s quality may always be quantified with the aid of numbers. We look for goods with better standards that strike the proper balance. The best quality product that gets highly appreciated and recommended by experienced users.

Customer ratings:  Would it be accurate to suggest that the medical skin protectants barrier creams were used by hundreds of customers before you? Superior ratings indicate that many customers had better service.

Customer Reviews: Like ratings,  provide you with accurate and reliable information about the product from genuine customers. Customer ratings are very important to all of us because they contain accurate and reliable information about the customer service we received from several hundred customers.

Seller Rank: This is very intriguing! Not only do you need a good medical skin protectants barrier creams, you also need a product with rising sales that is trendy. It accomplishes two goals. First, the expanding user base proves the quality of the product. Second, given that number, producers must be able to offer greater quality and after-sales support.

Value: You get what you pay for, they say, so consider the value. Cheap isn’t always good and expensive isn’t always bad. However, that does not imply that spending a lot of money on a product that is flashy but underwhelming is a good idea. Before adding them to the list, we make an effort to evaluate how much value you can get for your money from your medical skin protectants barrier creams.

Durability: Durability and reliability are closely related concepts. You will benefit from a strong and long-lasting medical skin protectants barrier creams for months and years to come.

Product availability: Products come and go, and new ones replace the old ones. Most likely, a few new features and required changes were made. What use is it to use a supposedly good product if the maker no longer supports it? We make an effort to highlight products that are current and offered by one or more trustworthy sellers, if not more.

Negative Reviews: Yes, we do take that into account as well! The goods with the majority of bad reviews are filtered out and disregarded when we choose the best-rated one on the market.

These are the standards by which we selected our medical skin protectants barrier creams. Do we end our process there? Hell no. The most crucial fact about us that you should be aware of is that we regularly update our website with current and pertinent information. We have one more layer of filtration since we place the greatest importance on reader satisfaction. Please let us know if any product included here is incorrect, irrelevant, subpar, or simply out of date. We always value your opinions, and we’ll work hard to make any necessary corrections to our list in response to them.

Why should you believe us?

There are now thousands of possibilities for these products on Amazon, but choosing the best one can be difficult and time-consuming. And what medical skin protectants barrier creams should you purchase in 2022?

This guide is the result of more than 10 years of experience in researching, testing and writing about many topics. Each member of our team is an authority in their area. We read every article we could find online and every consumer review on every retail website for seven hours. Additionally, we discovered a ton of websites that offered helpful resources, including buying tips and thorough information on medical skin protectants barrier creams.