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The 8 Best naproxen sodium of 2025

Are you trying to find naproxen sodium among various brands on the market but aren’t sure where to begin? To assist you in finding the right one, we’ve put together a list of the 7 best to help you pick the perfect one!

We investigated and evaluated a number of the top-selling naproxen sodium on the market in order to create our list of the best. Making a decision among the many options available is never simple. There are an infinite number of models available, each with a distinct price. And as you’ll find out, the best options aren’t usually the ones you imagine! This comparison is rich and relevant because of the numerous factors that were employed. You will find products featured in this ranking not only based on their pricing but also on their features and other customers reviews. To write this review, we completed 23 hours of research and did 20 naproxen sodium tests. You won’t need to pick products at random any more. If you’re unsure of what to look for, browse our list and consult the buying guide!

An overview of our top picks

Table of contents

The best naproxen sodium you can buy today

No. 1
Amazon Basic Care Naproxen Sodium Tablets 220 mg, Pain Reliever/Fever Reducer (NSAID), Muscular Aches, Backache, Headache, Toothache, Minor Arthritis Pain Relief & More, 300 Count (Packaging may vary)
  • ACTIVE INGREDIENT: This pain reliever and fever reducer contains naproxen sodium 220 mg, a nonsteroidal anti-inflammatory drug (NSAID); compare to the active ingredient in Aleve Caplets
  • STRENGTH TO LAST 12 HOURS: Pain reliever and fever reduction for up to 12 hours so you can get through the day
  • ACHES AND PAINS: Temporarily relieves minor aches and pains due to minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache and the common cold; also temporarily reduces fever
  • ALL DAY RELIEF: Amazon Basic Care Naproxen Sodium Tablets 220 mg is a pain reliever and fever reducer for adults and children age 12 years and over
  • CAPSULE-SHAPED TABLETS: This 12 hour pain reliever and fever reducer comes in a capsule-shaped tablet; this product is gluten free
No. 2
GoodSense Naproxen Sodium Tablets 220 mg, Pain Reliever and Fever Reducer (NSAID), 400 Count
  • ACTIVE INGREDIENT: This pain reliever and fever reducer contains naproxen sodium 220 mg, a nonsteroidal anti-inflammatory drug (NSAID); compare to the active ingredient in Aleve Caplets
  • STRENGTH TO LAST 12 HOURS: Pain reliever and fever reduction for up to 12 hours so you can get through the day
  • ACHES AND PAINS: Temporarily relieves minor aches and pains due to minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache and the common cold; also temporarily reduces fever.
  • ALL DAY RELIEF: GoodSense Naproxen Sodium Tablets 220 mg is a pain reliever and fever reducer for adults and children age 12 years and over
  • CAPSULE-SHAPED TABLETS: This 12 hour pain reliever and fever reducer comes in a capsule-shaped tablet; this product is gluten free
No. 3
Timely Naproxen Sodium 220 mg 300 Caplets - Compared to the Active Ingredients in All Day Strong Aleve - For Pain Relief, Fever Reducer, Minor Arthritis Pain Reliever, Menstrual Cramp Relief, Backache
  • ACTIVE INGREDIENT: With 220mg of Naproxen Sodium, this pain reliever and fever reducer provides temporary relief from minor pain of arthritis, backaches, and headaches.
  • 12 HOURS OF EXTENDED COMFORT: With strength to last 12 hours, Timely Naproxen Sodium ensures lasting relief, helping you power through the day by temporarily relieving muscular aches, backaches, headaches, toothaches, and minor pain of arthritis.
  • FOR ACHES AND PAINS: Get a deep and restful sleep during the night so you can face the next day feeling fresh. Our pain reliever temporarily alleviates a variety of discomforts including menstrual cramps, toothaches, and minor aches and pains due to the common cold.
  • FOR THE FAMILY: Suitable for both adults and teens aged 12 years and over, these caplets offer all-day relief for a wide range of pain and fever conditions. Each bottle comes with 300 caplets to provide long-term relief for the family.
  • NATIONAL BRAND EQUIVALENCY: Harnessing the power of Naproxen Sodium, its active ingredient is comparable to Aleve Caplets, providing an affordable alternative with the same active ingredient for effective pain management.
SaleNo. 4
HealthCareAisle Naproxen Sodium, 220 mg – 200 caplets – Pain Reliever and Fever Reducer, Up to 12 Hours of Relief
  • Naproxen Sodium caplets temporarily relieve minor aches and pains due to: minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache, the common cold; also temporarily reduces fever
  • Comparable to the national brand: Has the same active ingredient as Aleve Caplets*
  • Effective pain and fever relief for up to 12 hours
  • See package label for warnings, directions and other important information; use only as directed
No. 5
Amazon Basic Care Naproxen Sodium Caplets 220 mg, Fever Reducer (NSAID) and Pain Reliever for Muscular Aches, Backache, Headache, Toothache, Minor Arthritis and More, 90 Count
  • STRENGTH TO LAST 12 HOURS: Pain reliever and fever reduction for up to 12 hours so you can get through the day
  • ACHES AND PAINS: Temporarily relieves minor aches and pains due to minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache and the common cold; also temporarily reduces fever.
  • ALL DAY RELIEF: Amazon Basic Care Naproxen Sodium Tablets 220 mg is a pain reliever and fever reducer for adults and children age 12 years and over
  • CAPSULE-SHAPED TABLETS: This 12 hour pain reliever and fever reducer comes in a capsule-shaped tablet; this product is gluten free
SaleNo. 6
Amazon Basic Care Headache Pain Relief Naproxen Sodium Tablets 220 mg, Also Relieves Arthritis, Muscular Aches, Backache, Menstrual Cramps and Toothache, 90 Count
1,307 Consomer Reviews
Amazon Basic Care Headache Pain Relief Naproxen Sodium Tablets 220 mg, Also Relieves Arthritis, Muscular Aches, Backache, Menstrual Cramps and Toothache, 90 Count
  • ACTIVE INGREDIENT: The active ingredient in Amazon Basic Care Naproxen Sodium Tablets 220 mg, Headache Relief, is naproxen sodium 220 mg, a nonsteroidal anti-inflammatory drug (NSAID). Compare to Aleve Headache Pain Tablets active ingredient.
  • HEADACHE PAIN RELIEF and relief for ailments like minor pain of arthritis, backache, the common cold, muscular aches, menstrual cramps and toothache. Amazon Basic Care Naproxen Sodium Tablets 220 mg help you to keep going.
  • LASTS 12 HOURS: Amazon Basic Care Naproxen Sodium Tablets 220 mg have the strength to last 12 hours with just one dose
  • USE: Amazon Basic Care Naproxen Sodium Tablets 220 mg may be used as a pain reliever and fever reducer for adults and children 12 years and over
  • GLUTEN FREE: Amazon Basic Care Naproxen Sodium Tablets 220 mg are a gluten free option for temporary relief of minor aches and pains as well as fever reduction
No. 7
A+Health Naproxen Sodium 220 Mg Liquid Gels, Pain Reliever/Fever Reducer (NSAID), Made in USA, 180 Count
  • ACTIVE INGREDIENT NAPROXEN SODIUM: Contains active ingredient Naproxen 220mg (nonsteroidal anti-inflammatory drug) in an easy-to-swallow capsule—compare to the active ingredient in Aleve Liquid Gels
  • TEMPORARY PAIN RELIEF: Temporarily reduces fever and relieves minor pains due to headaches, toothaches, backaches, menstrual cramps, the common cold, muscular aches, and minor arthritis pain
  • LIQUID-FILLED CAPSULES: Our A+ Health Naproxen Sodium capsules are liquid-filled capsules which can provide rapid relief and get you back on track
  • 12 HOUR RELIEF: Proudly made in the USA using ingredients originating from various countries for 12 hour relief from most common aches and pains at a great value; Contains 180 capsules
  • FAST-ACTING: Don’t let pain get in your way! Find fast-acting relief on-the-go with these easy-to-swallow capsules so you can get back to living
No. 8
A+Health Naproxen Sodium 220 Mg Liquid Gels Back and Muscle Pain, Made in USA, 180 Count
  • ACTIVE INGREDIENT NAPROXEN SODIUM: Contains active ingredient Naproxen 220mg (nonsteroidal anti-inflammatory drug) in an easy-to-swallow capsule—compare to the active ingredient in Aleve Back & Muscle Pain
  • TEMPORARY PAIN RELIEF: Temporarily reduces fever and relieves minor pains due to backaches, menstrual cramps, and muscular aches, headaches, toothaches, the common cold, and minor arthritis pain
  • LIQUID-FILLED CAPSULES: Our A+ Health Naproxen Sodium Back & Muscle Pain Capsules are liquid-filled capsules which can provide rapid relief and get you back on track
  • 12 HOUR RELIEF: Proudly made in the USA using ingredients originating from various countries for 12 hour relief from most common aches and pains at a great value; Contains 180 capsules
  • EASY-TO-SWALLOW: Don’t let pain get in your way! Find fast-acting relief on-the-go with these easy-to-swallow capsules so you can get back to living
No. 10
VITACRUSH Signature Naproxen Sodium 220 mg., 400 Caplets
  • Naproxen Sodium Tablets USP, 220 mg active ingredient is 220 mg of Naproxen Sodium and may be used as a pain reliever/fever reducer for adults and children 12 years and over.
  • Signature Naproxen Sodium Tablets USP, 220 mg are a nonsteroidal anti-inflammatory drug (NSAID) and a gluten free product with strength to last 12 hours. Signature Naproxen Sodium Tablets USP, 220 mg should be taken in the smallest effective dose.
  • 400 Count
No. 11
GoodSense Naproxen Sodium Tablets 220 Mg, Headache Pain, Blue, 50 Count
  • Active ingredient: The active ingredient in Good Sense Naproxen Sodium tablets 220 mg, headache relief, is Naproxen Sodium 220 mg (Naproxen 200 mg), a nonsteroidal anti-inflammatory drug (NSAID). Compare to Aleve headache pain tablets active ingredient.
  • Headache pain relief and relief for ailments like minor pain of arthritis, backache, the common cold, muscular aches, menstrual cramps and toothache. Good Sense Naproxen Sodium tablets 220 mg help you to keep going.
  • 12 hours, one dose: don't let another 12 hours slip by without relief of headache and other minor aches, pains and fever. Good Sense Naproxen Sodium tablets 220 mg have the strength to last 12 hours with just one dose.
  • Use: Naproxen Sodium may be used as a pain reliever and fever reducer for adults and children 12 years and over.
  • Pain and fever: Good Sense Naproxen Sodium tablets 220 mg, headache pain are a gluten free option for temporary relief of minor aches and Pains as well as fever reduction.
No. 12
HealthCareAisle Naproxen Sodium, 220 mg - 225 caplets - Back and Muscle Pain Reliever, Up to 12 Hours of Relief
  • Naproxen Sodium caplets temporarily relieve minor aches and pains due to: backache, muscular aches, minor pain of arthritis, menstrual cramps, headache, toothache, the common cold; also temporarily reduces fever cramps, headache, toothache, the common cold; also temporarily reduces fever
  • Comparable to the national brand: Has the same active ingredient as Aleve Back and Muscle Pain Caplets*
  • Effective pain and fever relief for up to 12 hours
  • See package label for warnings, directions and other important information; use only as directed
SaleNo. 13
Aleve Pain Relief Naproxen Sodium Caplets ‐ 50 Count
  • LONG LASTING RELIEF: Each Aleve Tablet has the strength to last up to 12 hours
  • FEVER REDUCER: This pain medicine for adults and children ages 12 and up also temporarily reduces fever
  • EFFECTIVE PAIN RELIEVER: Temporarily reduces fever and relieves minor pain of arthritis, menstrual cramps, muscular aches, backache, toothache, headache and the common cold
  • DOCTOR RECOMMENDED: Aleve is the #1 orthopedic surgeon recommended OTC brand for minor arthritic pain.
  • EASY TO TAKE: Aleve Naproxen Tablets comes in small, round form that makes them easy to swallow
No. 14
Amazon Basic Care All Night Pain Relief PM, Naproxen Sodium, 220 mg/Diphenhydramine Hydrochloride, 25 mg Tablets, Pain Reliever/Nighttime Sleep-Aid, 160 Count
2,121 Consomer Reviews
Amazon Basic Care All Night Pain Relief PM, Naproxen Sodium, 220 mg/Diphenhydramine Hydrochloride, 25 mg Tablets, Pain Reliever/Nighttime Sleep-Aid, 160 Count
  • ACTIVE INGREDIENTS in this product are naproxen sodium 220 mg, a pain reliever, and diphenhydramine hydrochloride 25 mg, a nighttime sleep-aid. Compare to Aleve pm active ingredients.
  • NAPROXEN SODIUM PM from Amazon Basic Care pairs diphenhydramine HCl 25 mg, a nighttime sleep-aid, with the 12-hour pain relief of naproxen sodium 220 mg to help you fall asleep and stay asleep.
  • THE ACHES AND PAINS of the day can follow you into nighttime and prevent a good night's rest. The active ingredient naproxen sodium 220 mg is a NSAID (nonsteroidal anti-inflammatory drug) pain reliever.
  • FALLING ASLEEP AND STAYING ASLEEP can be tough when aches and pains plague you in the nighttime. The active ingredient diphenhydramine hydrochloride 25 mg is a nighttime sleep-aid. Get the rest you need tonight for a better tomorrow.
  • Amazon Basic Care NAPROXEN SODIUM PM CAPLETS: This nighttime product is for occasional sleeplessness associated with minor aches and pain for adults and children 12 years and over. capsule-shaped tablets
SaleNo. 15
Aleve Gelcaps with Easy Open Arthritis Cap, Naproxen Sodium, Arthritis Pain Relief Medicine, Medication for Arthritis Pain, 160 Count
  • Up to 12-Hours of Uninterrupted Pain Relief: Aleve Pain Reliever & Fever Reducer Gelcaps provide long-lasting arthritis pain relief, as well as relief from muscular aches, backache, menstrual cramps, headache, toothache, and the common cold
  • Easy Open Arthritis Cap: Specially designed arthritis bottle features an easy to open, cushionedcovered cap and contoured bottle for better control when your arthritis acts up. Package is not child-resistant
  • Fever Reducer: Temporarily reduces fever for adults and children aged 12 and up
  • Targeted Pain Relief: naproxen sodium relieves minor pain from arthritis
  • Doctor Recommended: #1 orthopedic doctor recommended OTC brand for minor arthritic pain*
  • Effective Pain Reliever: In a study, proven as effective and longer lasting than a common Rx pain reliever. Ask a doctor if Aleve is right for you
No. 16
Aleve Back & Muscle Pain Relief Naproxen Sodium Tablets, Pain Reliever & Fever Reducer, Medicine for Body , 250 Count
6,046 Consomer Reviews
Aleve Back & Muscle Pain Relief Naproxen Sodium Tablets, Pain Reliever & Fever Reducer, Medicine for Body , 250 Count
  • Up to 12-Hours of Uninterrupted Pain Relief: Aleve Back & Muscle Pain Relief Tablets provide long-lasting back pain and muscle pain relief
  • Fever Reducer: Temporarily reduces fever for adults and children aged 12 and up
  • Targeted Pain Relief: Every tablet is made with 220 mg of naproxen sodium to help you take on muscle pain and provide back pain relief
  • Doctor Recommended: From the #1 orthopedic doctor recommended OTC brand for minor arthritis pain*
  • Effective Pain Reliever: In a study, proven as effective and longer lasting than a common Rx pain reliever. Ask a doctor if Aleve is right for you
  • Comes in small, easy-to-swallow tablets; use as directed
No. 18
Aleve Pain Reliever & Fever Reducer Naproxen Sodium Caplets, Body Pain Relief, Arthritis Pain Relief, Pain Medicine for Adults and Children Ages 12 and Up, 60 Individual Pouches
  • On the Go: Take the power of Aleve with you, anywhere you go
  • Up to 12-Hours of Uninterrupted Pain Relief: Aleve Pain Reliever & Fever Reducer Gelcaps provide long-lasting pain relief of muscle pain, arthritis & joint pain, backache, toothache, menstrual cramps, and headache
  • Fever Reducer: Temporarily reduces fever for adults and children aged 12 and up
  • Targeted Pain Relief: Relieves minor pain from arthritis, muscular aches, backache, headache, and the common cold
  • Doctor Recommended: Aleve is the #1 orthopedic doctor recommended OTC pain relief brand for minor arthritic pain*; use as directed
  • Effective Pain Reliever: In a study, proven as effective and longer lasting than a common Rx pain reliever. Ask a doctor if Aleve is right for you
SaleNo. 20
Member's Mark 220 mg Naproxen Sodium (400 ct.) by Members Mark
  • Compare to the active ingredient in Aleve
  • Pain reliever
  • Fever reducer
  • Strength to last 12 hours

How to choose a good naproxen sodium

Does the idea of finding a fantastic naproxen sodium make you anxious? When it comes to purchasing this product, specifically when deciding which model to select, has your head been spinning between options? You are not alone if that is the case. We are aware of the pressure involved in the purchasing process!

Your presence here indicates that you are interested in naproxen sodium. Before choosing which product would be the best for your needs after being inundated with information, locate a reliable source with genuine selections. You can get that information from a variety of sources, including buying guides and rating websites, word-of-mouth recommendations from friends and family, online discussion forums where users can share their own experiences, product reviews that can be found all over the internet, and YouTube channels. You can only get the right product through exhaustive analysis. But you realize that’s not always simple. In order to ease your concerns, we have taken the time to develop a list of the top naproxen sodium products available right now. You might be wondering how we came up with the list. How was this buying guide developed?

First, we used our algorithms to gather as much reliable data as we could about these products. To verify all the data gathered, we used both artificial intelligence and a lot of algorithms.
Then, our experts used criteria that are recognized in the business to evaluate them according to their quality to price ratio, allowing us to choose the top naproxen sodium on the market right now!

The selection of the goods is not arbitrary. Before creating a list, we take into account a number of factors. Below are some of the criteria discussed:

Brand Value: What happens if you choose a dubious brand just because it appears to be a good deal? So the likelihood of receiving a product with a short shelf life increases. That is due to the fact that well-known brands have a reputation to uphold, while others do not. Top naproxen sodium brands strive to provide some distinctive traits that set them apart from the competition. So, hopefully one or more of the items on our list will be perfect for you.

Features: Useful features are all you need, not tons of them. We consider the important aspects and select the top naproxen sodium based on those.

Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products with higher specifications, but with the right balance.

Quality: A product’s quality may always be quantified with the aid of numbers. We look for goods with better standards that strike the proper balance. The best quality product that gets highly appreciated and recommended by experienced users.

Customer ratings:  Would it be accurate to suggest that the naproxen sodium were used by hundreds of customers before you? Superior ratings indicate that many customers had better service.

Customer Reviews: Like ratings,  provide you with accurate and reliable information about the product from genuine customers. Customer ratings are very important to all of us because they contain accurate and reliable information about the customer service we received from several hundred customers.

Seller Rank: This is very intriguing! Not only do you need a good naproxen sodium, you also need a product with rising sales that is trendy. It accomplishes two goals. First, the expanding user base proves the quality of the product. Second, given that number, producers must be able to offer greater quality and after-sales support.

Value: You get what you pay for, they say, so consider the value. Cheap isn’t always good and expensive isn’t always bad. However, that does not imply that spending a lot of money on a product that is flashy but underwhelming is a good idea. Before adding them to the list, we make an effort to evaluate how much value you can get for your money from your naproxen sodium.

Durability: Durability and reliability are closely related concepts. You will benefit from a strong and long-lasting naproxen sodium for months and years to come.

Product availability: Products come and go, and new ones replace the old ones. Most likely, a few new features and required changes were made. What use is it to use a supposedly good product if the maker no longer supports it? We make an effort to highlight products that are current and offered by one or more trustworthy sellers, if not more.

Negative Reviews: Yes, we do take that into account as well! The goods with the majority of bad reviews are filtered out and disregarded when we choose the best-rated one on the market.

These are the standards by which we selected our naproxen sodium. Do we end our process there? Hell no. The most crucial fact about us that you should be aware of is that we regularly update our website with current and pertinent information. We have one more layer of filtration since we place the greatest importance on reader satisfaction. Please let us know if any product included here is incorrect, irrelevant, subpar, or simply out of date. We always value your opinions, and we’ll work hard to make any necessary corrections to our list in response to them.

Why should you believe us?

There are now thousands of possibilities for these products on Amazon, but choosing the best one can be difficult and time-consuming. And what naproxen sodium should you purchase in 2022?

This guide is the result of more than 10 years of experience in researching, testing and writing about many topics. Each member of our team is an authority in their area. We read every article we could find online and every consumer review on every retail website for seven hours. Additionally, we discovered a ton of websites that offered helpful resources, including buying tips and thorough information on naproxen sodium.