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The 8 Best pycnogenol nutritional supplements of 2025

Are you trying to find pycnogenol nutritional supplements among various brands on the market but aren’t sure where to begin? To assist you in finding the right one, we’ve put together a list of the 7 best to help you pick the perfect one!

We investigated and evaluated a number of the top-selling pycnogenol nutritional supplements on the market in order to create our list of the best. Making a decision among the many options available is never simple. There are an infinite number of models available, each with a distinct price. And as you’ll find out, the best options aren’t usually the ones you imagine! This comparison is rich and relevant because of the numerous factors that were employed. You will find products featured in this ranking not only based on their pricing but also on their features and other customers reviews. To write this review, we completed 11 hours of research and did 58 pycnogenol nutritional supplements tests. You won’t need to pick products at random any more. If you’re unsure of what to look for, browse our list and consult the buying guide!

An overview of our top picks

Table of contents

The best pycnogenol nutritional supplements you can buy today

No. 1
Life Extension Pycnogenol – French Maritime Pine Bark Extract – Scientifically Studied healthy aging & Vascular Health Supplement – Non-GMO, Gluten-Free, Vegetarian – 60 Capsules
  • Supports vascular health – Pycnogenol supports healthy aging and cardiovascular health by encouraging healthy nitric oxide levels, which supports endothelial function and circulation.
  • What Is Pycnogenol? Life Extension’s Pycnogenol helps your body fight back against the normal aging process to support overall health, promoting healthy circulation and blood vessel function.
  • Provides antioxidant protection – Pycnogenol helps fight free radicals, protecting the body from oxidative stress. This protects biological systems, including cells, tissues, organs and DNA.
  • Ingredients matter – We use only the finest raw ingredients with the purity and potency you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
  • Live your healthiest life – We believe the answers to a healthier life are within reach, and that scientific research is the key to getting us there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies
SaleNo. 2
NOW Foods Supplements, Pycnogenol 100 mg (a Unique Combination of Proanthocyanidins from French Maritime Pine) with Amla, 60 Veg Capsules
  • FREE RADICAL SCAVENGER/WITH 240 mg AMLA EXTRACT: NOW Pycnogenol 100 mg supports a healthy, balanced immune system response, and promotes the production of collagen, hyaluronic acid, and nitric oxide.
  • CLASSIFICATIONS/CERTIFICATIONS: Non-GMO, Kosher, Dairy Free, Egg Free, Made without Gluten, Nut Free, Soy Free, Vegan/Vegetarian
  • HEALTHY VASCULAR FUNCTION/BALANCED IMMUNE RESPONSE: Clinical and non-clinical studies have demonstrated that Pycnogenol can help to maintain healthy eyes, skin, and joints, and can support normal vascular structure and function. Take 1 capsule 1 to 2 times daily.
  • With Amla
  • Kosher
SaleNo. 3
NOW Foods Supplements, Pycnogenol 60 mg (a Unique Combo of Proanthocyanidins from French Maritime Pine) with Acerola & Rutin Powder, 50 Veg Capsules
  • FREE RADICAL SCAVENGER/WITH 200 mg ACEROLA POWDER AND 240 mg RUTIN POWDER: Pycnogenol helps to protect the body's tissues from oxidative stress and supports a healthy, balanced immune system response to normal metabolic stress.
  • HEALTHY VASCULAR FUNCTION/BALANCED IMMUNE RESPONSE: Scientific studies have shown that Pycnogenol helps to maintain vascular strength and function. Take 1 capsule 1 to 3 times daily.
  • CLASSIFICATIONS/CERTIFICATIONS: Non-GMO, Kosher, Dairy Free, Egg Free, Made without Gluten, Nut Free, Soy Free, Vegan/Vegetarian
  • With Acerola and Rutin Powder
  • Pycnogenol Horphag Research
No. 4
Carlyle Pycnogenol 100mg | 30 Capsules | French Maritime Pine Bark Extract | Pinus Pinaster | Non-GMO and Gluten Free Supplement
  • ABOUT PYCNOGENOL: Also known as French Maritime Pine Bark Extract, derived from the Maritime tree
  • STANDARDIZED EXTRACT: Features 100mg Pycnogenol per serving in convenient quick release capsules
  • ROOTED IN WELLNESS: Carlyle provides premium, honest supplements in your pursuit to healthy living
  • CARLYLE MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
  • NATURALLY FREE OF: Gluten, Wheat, Yeast, Lactose, Soy, Artificial Flavor, Preservatives and Non-GMO
SaleNo. 5
NOW Foods Supplements, Pycnogenol 30 mg (a Unique Combination of Proanthocyanidins from French Maritime Pine) with 300 mg Bioflavonoids, 60 Veg Capsules
  • Pycnogenol is a unique combination of proanthocyanidins obtained from the bark of the French maritime pine
  • As a potent scavenger of free radicals, Pycnogenol helps to maintain healthy cellular structures and supports a healthy, balanced immune system response to normal metabolic stress*
  • Through these mechanisms, Pycnogenol helps to maintain healthy eye, skin, and joint tissues*
  • Take 2 capsules 1 to 3 times daily
  • Packaged in the USA by a family owned and operated company since 1968.
No. 6
Pure Encapsulations Pycnogenol 100 mg | Hypoallergenic Supplement to Promote Vascular Health and Provide Antioxidant Support | 30 Capsules
  • Antioxidants: Pycnogenol is a pine bark extract with antioxidant properties.*
  • Vascular Integrity: Supports the health of blood vessels, overall vascular health, stabilization of collagenous membranes and vascular integrity. It also promotes vascular function by modulating nitric oxide levels.*
  • Superoxide Radical Scavenger: In addition to facilitating vitamin C regeneration and preserving vitamin E, Pycnogenol is a hydroxyl and superoxide radical scavenger.*
  • Pure Quality: Our supplements are made with only premium ingredients sourced from trusted suppliers and guided by our nutritional experts, then carefully manufactured and tested to verify their potency and purity.
  • Pure Difference: What makes us different isn't just our process or what goes into our supplements -- what we leave out matters, too. Pure Encapsulations products are FREE FROM wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.
SaleNo. 7
The Pycnogenol Phenomenon: The Most Unique & Versatile Health Supplement
  • Rohdewald Ph.D., Peter (Author)
  • English (Publication Language)
  • 178 Pages - 11/23/2015 (Publication Date) - Basic Health Publications, Inc. (Publisher)
SaleNo. 8
Natrol Pycnogenol Capsules, Antioxidant Protection, Supplement Protects Against Cellular Oxidation and Age-Related Damage, European Maritime Pine Bark Extract, Supports Circulation, 50 mg, 60 Count
  • Specifically known for supporting the immune system and aiding in healthy circulation.*
  • Pycnogenol is an antioxidant that helps protect cells from environmental and age-related oxidative stress.*
  • Pycnogenol is extracted with non-toxic materials from the Maritime Pine Tree, which is grown without herbicides or pesticides,
  • Pycnogenol contains 60% proanthocyanidins, which are in the flavonoid family and known for their health benefit.*
  • Natrol is the #1 drug-free sleep aid brand^ and a leader in Mood & Stress.
SaleNo. 9
Country Life Pycnogenol 100mg - French Maritime Pine Bark Extract Antioxidants Supplement - Supports Cardiovascular Health - No Yeast, Corn, Wheat, Soy, Milk, Salt, Preservatives - 30 Capsules
  • Includes Antioxidants From Pine Bark Extract: Fortify your health with Pycnogenol 100mg, packed with powerful oligomeric proanthocyanidins (OPCs) that act as antioxidants, protecting your cells from damage and aging.
  • Supports Cardiovascular Health: Prioritize your heart's health with our French Maritime Pine Bark extract, a natural supplement known to boost cardiovascular function and promote overall wellness, providing crucial support for a healthier life.
  • Pure & Natural Ingredients: Experience the benefits of Country Life's Pycnogenol supplements, free from yeast, corn, wheat, soy, milk, salt, preservatives, and artificial colors, ensuring you get only the purest, high-quality supplement.
  • Country Life Pledge OF integrity: Trust in our commitment to purity and quality with each bottle of Pycnogenol French Maritime Pine Bark extract, giving you peace of mind with guaranteed consistency and effectiveness in every dose.
  • Convenient Daily Dosage: Comes in an easy-to-take 30-capsule bottle, providing a 100mg dose of Pycnogenol per capsule for consistent, reliable support.
No. 10
OPC-3 Isotonix - Antioxidant Supplement - Pycnogenol, Grape Seed Extracts, Bilberry, Red Wine & Pine Bark Extracts - for Heart & Circulatory Support - 90 Servings
  • ✔ Powerful Antioxidant Supplement – This premium antioxidant supplement contains grape seed extract, Pycnogenol supplements, red wine extract, bilberry extract, and pine bark to fight oxidative stress and free radicals.
  • ✔ Fast-Absorbing Powder Formula – Unlike traditional capsules, this grape seed extract powder is mixed with water for an isotonic liquid supplement, ensuring up to 95% nutrient absorption for superior results.
  • ✔ Heart & Circulatory Health Support – Formulated with grape seed extract and Pycnogenol, this supplement promotes cardiovascular health, supports cholesterol levels, and enhances circulation by strengthening blood vessels.
  • ✔ Supports Joint & Eye Health – This antioxidant supplement aids joint flexibility, reduces mild menstrual cramping, and enhances vision by supporting healthy blood vessel dilation.
  • ✔ High-Quality & Vegan-Friendly – Made with grapeseed extract powder, this supplement is free from gluten, GMOs, and artificial additives. Manufactured under GMP standards for maximum purity and potency.
No. 11
Piping Rock Pycnogenol Supplement | 50 mg | 60 Capsules | French Maritime Pine Bark Extract | Pinus Pinaster for Men and Women | Non-GMO, Gluten Free
  • Also known as French Maritime Pine Bark Extract, derived from the Maritime tree
  • Features 50mg Pycnogenol per serving in convenient quick release capsules
  • Devoted to Purity, Potency and Safety!
  • Non-GMO and Gluten Free
  • Laboratory Tested, using Trusted Ingredients
No. 12
Pure Encapsulations Pycnogenol (Pine Bark Extract) 50 mg | Hypoallergenic Supplement to Support Cognitive Function and Cardiovascular Health | 120 Capsules
  • Antioxidants: Pycnogenol is a pine bark extract with antioxidant properties for vascular health.*
  • Vascular Integrity: Supports the health of blood vessels, overall vascular health, stabilization of collagenous membranes and vascular integrity. It also promotes vascular function by modulating nitric oxide levels.*
  • Superoxide Radical Scavenger: In addition to facilitating vitamin C regeneration and preserving vitamin E, Pycnogenol is a hydroxyl and superoxide radical scavenger.*
  • Pure Quality: Our supplements are made with only premium ingredients sourced from trusted suppliers and guided by our nutritional experts, then carefully manufactured and tested to verify their potency and purity.
  • Pure Difference: What makes us different isn't just our process or what goes into our supplements -- what we leave out matters, too. Pure Encapsulations products are FREE FROM wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.
No. 13
Source Naturals Pycnogenol & Grape Seed Extract 100 mg Dietary Supplement - 30 Tablets - a Potent Combination of Two Powerful Natural antioxidants*
  • Both extracts contain proanthocyanidins, a special class of water-soluble bioflavonoids which are excellent free radical scavengers. Proanthocyanidins possess many properties that may be beneficial in maintaining good health.
  • Suggested Use:. 1 tablet 1 to 3 times daily.
  • Well Made Supplement:Contains no yeast, dairy, egg, gluten, corn, soy, or wheat. Contains no sugar, starch, salt, preservatives or artificial color, flavor, or fragrance.
  • Over 40 Years of Trust. Source Naturals was created in 1982 by CEO Ira Goldberg to support everyone’s potential to enjoy optimal health.
  • Manufactured in the USA. Manufactured in Scotts Valley, CA, under the Good Manufacturing Practices (cGMPs) established by the US Food and Drug Administration. (FDA)
No. 14
Patient One Pycnogenol OPC Complex 300mg | Supplement to Support Vascular Health and Healthy Aging* | French Maritime Pine Bark and More | 30 Capsules
  • Heart Health and Vein Support: Promotes healthy blood circulation, blood flow, blood vessel diameter and nitric oxide production, while maintaining already healthy cholesterol levels*
  • Healthy Aging: Supports youthful, healthy skin and healthy joint function*
  • Super Antioxidant Formula with Polyphenols: 100 mg Pycnogenol French maritime pine bark, plus bilberry, grapeseed, red wine extract and a citrus bioflavonoid complex
  • Clean and Pure: Vegetarian formula free of milk, egg, fish, peanuts, crustacean shellfish, soy, tree nuts, wheat, sesame, gluten and GMOs
  • About Patient One: As a leading healthcare professional brand, Patient One is trusted by thousands of practitioners for our premium quality supplements. Our research-driven formulas are made with high quality raw ingredients, manufactured in an NSF-certified, GMP facility to stringent quality standards, and rigorously tested at all stages.
No. 15
BlueBonnet Pycnogenol Vegetarian Capsules, 100 mg, 60 Count (743715008366)
  • 100 mg of Pycnogenol from pine bark extract
  • Vascular Health ♦ Cellular Protection ♦
  • 60 Vegetable Capsules, 60 Servings
  • Soy-Free, Gluten-Free, Non-GMO, Kosher Parve
  • Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat and soybeans. Also free of corn, gluten, barley, rice, sodium and sugar.
No. 16
BLUEBONNET NUTRITION PYCNOGENOL 50 mg
  • Contains 50 mg of Pycnogenol from pine bark extract
  • Healthy Vascular Function Balanced Immune Response
  • 60 Vegetable Capsules,, 60 Servings
  • Soy-Free, Gluten-Free, Non-GMO, Kosher Certified, Vegan
  • Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat and soybeans. Also free of corn, yeast, gluten, barley, rice, sodium and sugar
No. 17
Patient One Pycnogenol OPC Complex 300mg | Supplement to Support Vascular Health and Healthy Aging* | French Maritime Pine Bark and More | 60 Capsules
  • Heart Health and Vein Support: Promotes healthy blood circulation, blood flow and nitric oxide production, while maintaining already healthy cholesterol levels*
  • Healthy Aging: Supports youthful, healthy skin and healthy joint function*
  • Super Antioxidant Formula with Polyphenols: 100 mg Pycnogenol French maritime pine bark, plus bilberry, grapeseed, red wine extract and a citrus bioflavonoid complex
  • Clean and Pure: Vegetarian formula free of milk, egg, fish, peanuts, crustacean shellfish, soy, tree nuts, wheat, sesame, gluten and GMOs
  • About Patient One: As a leading healthcare professional brand, Patient One is trusted by thousands of practitioners for our premium quality supplements. Our research-driven formulas are made with high quality raw ingredients, manufactured in an NSF-certified, GMP facility to stringent quality standards, and rigorously tested at all stages.
No. 18
BLUEBONNET NUTRITION PYCNOGENOL 100 mg
  • Contains 100 mg of Pycnogenol from pine bark extract
  • Healthy Vascular Function Balanced Immune Response
  • 30 Vegetable Capsules, 30 Servings
  • Soy-Free, Gluten-Free, Non-GMO, Kosher Certified, Vegan
  • Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat and soybeans. Also free of corn, yeast, gluten, barley, rice, sodium and sugar
SaleNo. 19
Life Extension Arterial Protect - Blood Pressure Supplement for Heart Health - with gotu kola and Pycnogenol dried French maritime pine bark extracts - Gluten-Free, Non-GMO, Vegetarian - 30 capsules
  • Healthy blood flow, happy heart—Over time, fats and cellular waste can accumulate in your blood vessels, forming plaque in the arteries. By encouraging the health of the delicate inner lining of your arteries (the endothelium), this heart health supplement promotes plaque stability, encourages a healthy inflammatory response and protects cells against oxidative stress caused by free radicals.
  • Keep the beat going—The combination of gotu kola and Pycnogenol dried French maritime bark extract has been clinically studied as a blood pressure support supplement. Gotu kola and Pycnogenol extract helps maintain the health and function of your arteries. They also help modulate collagen production, help protect against oxidative stress and inhibit inflammatory factors to promote circulatory and vascular health.
  • Convenient, once-daily heart support—Encourage your body’s natural process for regulating plaque in the arteries and maintaining healthy blood flow from head to toe with this innovative blood pressure supplement. It’s formulated with potent botanical nutrients—making it the perfect complement to your heart-healthy lifestyle.
  • Ingredients matter—Sourced using only the finest raw ingredients with the purity and potency your body deserves. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every product we produce.
  • Live your healthiest life—For over 40 years, we’ve been developing advanced, effective formulas made with the highest standards and based on the latest scientific findings. We believe the answers to a healthier, richer life are within reach, and that rigorous scientific research is the path to get us there. That’s why so many of our nutritional formulas are designed using specific ingredients and amounts based on scientific studies.

How to choose a good pycnogenol nutritional supplements

Does the idea of finding a fantastic pycnogenol nutritional supplements make you anxious? When it comes to purchasing this product, specifically when deciding which model to select, has your head been spinning between options? You are not alone if that is the case. We are aware of the pressure involved in the purchasing process!

Your presence here indicates that you are interested in pycnogenol nutritional supplements. Before choosing which product would be the best for your needs after being inundated with information, locate a reliable source with genuine selections. You can get that information from a variety of sources, including buying guides and rating websites, word-of-mouth recommendations from friends and family, online discussion forums where users can share their own experiences, product reviews that can be found all over the internet, and YouTube channels. You can only get the right product through exhaustive analysis. But you realize that’s not always simple. In order to ease your concerns, we have taken the time to develop a list of the top pycnogenol nutritional supplements products available right now. You might be wondering how we came up with the list. How was this buying guide developed?

First, we used our algorithms to gather as much reliable data as we could about these products. To verify all the data gathered, we used both artificial intelligence and a lot of algorithms.
Then, our experts used criteria that are recognized in the business to evaluate them according to their quality to price ratio, allowing us to choose the top pycnogenol nutritional supplements on the market right now!

The selection of the goods is not arbitrary. Before creating a list, we take into account a number of factors. Below are some of the criteria discussed:

Brand Value: What happens if you choose a dubious brand just because it appears to be a good deal? So the likelihood of receiving a product with a short shelf life increases. That is due to the fact that well-known brands have a reputation to uphold, while others do not. Top pycnogenol nutritional supplements brands strive to provide some distinctive traits that set them apart from the competition. So, hopefully one or more of the items on our list will be perfect for you.

Features: Useful features are all you need, not tons of them. We consider the important aspects and select the top pycnogenol nutritional supplements based on those.

Specifications: Numbers always help you measure the quality of a product in a quantitative way. We try to find products with higher specifications, but with the right balance.

Quality: A product’s quality may always be quantified with the aid of numbers. We look for goods with better standards that strike the proper balance. The best quality product that gets highly appreciated and recommended by experienced users.

Customer ratings:  Would it be accurate to suggest that the pycnogenol nutritional supplements were used by hundreds of customers before you? Superior ratings indicate that many customers had better service.

Customer Reviews: Like ratings,  provide you with accurate and reliable information about the product from genuine customers. Customer ratings are very important to all of us because they contain accurate and reliable information about the customer service we received from several hundred customers.

Seller Rank: This is very intriguing! Not only do you need a good pycnogenol nutritional supplements, you also need a product with rising sales that is trendy. It accomplishes two goals. First, the expanding user base proves the quality of the product. Second, given that number, producers must be able to offer greater quality and after-sales support.

Value: You get what you pay for, they say, so consider the value. Cheap isn’t always good and expensive isn’t always bad. However, that does not imply that spending a lot of money on a product that is flashy but underwhelming is a good idea. Before adding them to the list, we make an effort to evaluate how much value you can get for your money from your pycnogenol nutritional supplements.

Durability: Durability and reliability are closely related concepts. You will benefit from a strong and long-lasting pycnogenol nutritional supplements for months and years to come.

Product availability: Products come and go, and new ones replace the old ones. Most likely, a few new features and required changes were made. What use is it to use a supposedly good product if the maker no longer supports it? We make an effort to highlight products that are current and offered by one or more trustworthy sellers, if not more.

Negative Reviews: Yes, we do take that into account as well! The goods with the majority of bad reviews are filtered out and disregarded when we choose the best-rated one on the market.

These are the standards by which we selected our pycnogenol nutritional supplements. Do we end our process there? Hell no. The most crucial fact about us that you should be aware of is that we regularly update our website with current and pertinent information. We have one more layer of filtration since we place the greatest importance on reader satisfaction. Please let us know if any product included here is incorrect, irrelevant, subpar, or simply out of date. We always value your opinions, and we’ll work hard to make any necessary corrections to our list in response to them.

Why should you believe us?

There are now thousands of possibilities for these products on Amazon, but choosing the best one can be difficult and time-consuming. And what pycnogenol nutritional supplements should you purchase in 2022?

This guide is the result of more than 10 years of experience in researching, testing and writing about many topics. Each member of our team is an authority in their area. We read every article we could find online and every consumer review on every retail website for seven hours. Additionally, we discovered a ton of websites that offered helpful resources, including buying tips and thorough information on pycnogenol nutritional supplements.